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ZINC Item

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50666204

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[[2-oxo-2-(prop-2-ynylamino)ethyl]carbamoyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[[2-oxo-2-(prop-2-ynyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.43	2.82	-22.84	3	7	0	97	329.356	6	↓ MOL2 SDF SMILES Flexibase

50666206

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[[2-oxo-2-(prop-2-ynylamino)ethyl]carbamoyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[[2-oxo-2-(prop-2-ynyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.43	2.8	-22.72	3	7	0	97	329.356	6	↓ MOL2 SDF SMILES Flexibase

35634990

Analogs

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Popular Name: (2S)-N-[4-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	5.24	-44.14	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35634991

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[4-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	5.24	-45.19	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35634992

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	5.22	-45.41	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35634993

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	5.22	-44.41	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35635108

Analogs

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Popular Name: (2S)-N-[4-[(1S)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1S)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	6.08	-43.02	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635109

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[4-[(1R)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1R)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	6.07	-44.04	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635110

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1S)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1S)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	6.06	-44.26	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635111

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1R)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1R)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	6.06	-43.34	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635188

Analogs

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Popular Name: (2S)-N-[4-[(1S)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1S)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	6.84	-43.73	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635189

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[4-[(1R)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-[(1R)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	6.83	-44.75	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635190

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1S)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1S)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	6.82	-44.97	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635191

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[4-[(1R)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-[(1R)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	6.81	-43.99	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635334

Analogs

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Popular Name: (2S)-N-[3-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	5.24	-49.39	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35635335

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	5.24	-50.31	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35635336

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	5.22	-50.81	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35635337

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	5.21	-49.9	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35635450

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[(1S)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1S)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.08	-48.22	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635451

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[(1R)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1R)-1-(ethylamino)et…

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Activity (Go SEA)

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.07	-49.09	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635452

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1S)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1S)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.06	-49.56	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635453

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1R)-1-(ethylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1R)-1-(ethylamino)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.06	-48.74	3	4	1	55	263.361	5	↓ MOL2 SDF SMILES Flexibase

35635528

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[(1S)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1S)-1-(propylamino)e…

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Activity (Go SEA)

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.84	-48.97	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635529

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[3-[(1R)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[3-[(1R)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.83	-49.86	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635530

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1S)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1S)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.82	-50.34	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35635531

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[3-[(1R)-1-(propylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[3-[(1R)-1-(propylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.81	-49.48	3	4	1	55	277.388	6	↓ MOL2 SDF SMILES Flexibase

35643410

Analogs

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Popular Name: (2S)-N-[2-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[2-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	5.53	-53.43	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35643413

Analogs

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Popular Name: (2S)-N-[2-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[2-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	5.54	-51.55	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35643416

Analogs

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Popular Name: (2R)-N-[2-[(1S)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[2-[(1S)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	5.52	-55.09	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

35643418

Analogs

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Popular Name: (2R)-N-[2-[(1R)-1-(methylamino)ethyl]phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[2-[(1R)-1-(methylamino)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	5.51	-53.6	3	4	1	55	249.334	4	↓ MOL2 SDF SMILES Flexibase

19433000

Analogs

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Popular Name: N-(3-Amino-4-methylphenyl)tetrahydro-2-furancarboxamide N-(3-Amino-4-methylphenyl)tetrah…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	3.2	-14.9	3	4	0	64	220.272	2	↓ MOL2 SDF SMILES Flexibase

19433002

Analogs

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Popular Name: N-(3-Amino-4-methylphenyl)tetrahydro-2-furancarboxamide N-(3-Amino-4-methylphenyl)tetrah…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	3.2	-14.93	3	4	0	64	220.272	2	↓ MOL2 SDF SMILES Flexibase

19436480

Analogs

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Popular Name: (2S)-N-[2-(N-hydroxy-C-methyl-carbonimidoyl)phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[2-(N-hydroxy-C-methyl-ca…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.41	3.7	-15.46	2	5	0	71	248.282	3	↓ MOL2 SDF SMILES Flexibase

19436482

Analogs

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Popular Name: (2R)-N-[2-(N-hydroxy-C-methyl-carbonimidoyl)phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[2-(N-hydroxy-C-methyl-ca…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.41	3.68	-15.19	2	5	0	71	248.282	3	↓ MOL2 SDF SMILES Flexibase

19438433

Analogs

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Popular Name: (2S)-N-(3-carbamothioylphenyl)tetrahydrofuran-2-carboxamide (2S)-N-(3-carbamothioylphenyl)te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	3.8	-32.91	3	4	0	64	250.323	3	↓ MOL2 SDF SMILES Flexibase

19438435

Analogs

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Popular Name: (2R)-N-(3-carbamothioylphenyl)tetrahydrofuran-2-carboxamide (2R)-N-(3-carbamothioylphenyl)te…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	3.85	-30.69	3	4	0	64	250.323	3	↓ MOL2 SDF SMILES Flexibase

19438549

Analogs

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Popular Name: 2-[[4-[[(2S)-tetrahydrofuran-2-carbonyl]amino]benzoyl]amino]acetic 2-[[4-[[(2S)-tetrahydrofuran-2-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.98	2.79	-57.15	2	7	-1	108	291.283	5	↓ MOL2 SDF SMILES Flexibase

19438551

Analogs

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Popular Name: 2-[[4-[[(2R)-tetrahydrofuran-2-carbonyl]amino]benzoyl]amino]acetic 2-[[4-[[(2R)-tetrahydrofuran-2-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.98	2.83	-56.89	2	7	-1	108	291.283	5	↓ MOL2 SDF SMILES Flexibase

36110545

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	5.75	-16.68	1	5	0	65	283.711	4	↓ MOL2 SDF SMILES Flexibase

36110546

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	5.73	-17	1	5	0	65	283.711	4	↓ MOL2 SDF SMILES Flexibase

19991903

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Popular Name: (2S)-N-(2-hydroxy-5-nitro-phenyl)tetrahydrofuran-2-carboxamide (2S)-N-(2-hydroxy-5-nitro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.16	2.83	-25.15	2	7	0	104	252.226	3	↓ MOL2 SDF SMILES Flexibase

19991907

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Popular Name: (2R)-N-(2-hydroxy-5-nitro-phenyl)tetrahydrofuran-2-carboxamide (2R)-N-(2-hydroxy-5-nitro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.16	2.88	-24.54	2	7	0	104	252.226	3	↓ MOL2 SDF SMILES Flexibase

36139086

Analogs

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Popular Name: (2S)-N-(2-cyano-3-fluoro-phenyl)tetrahydrofuran-2-carboxamide (2S)-N-(2-cyano-3-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.31	5.18	-9.49	1	4	0	62	234.23	2	↓ MOL2 SDF SMILES Flexibase

36139089

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Popular Name: (2R)-N-(2-cyano-3-fluoro-phenyl)tetrahydrofuran-2-carboxamide (2R)-N-(2-cyano-3-fluoro-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.31	5.18	-9.96	1	4	0	62	234.23	2	↓ MOL2 SDF SMILES Flexibase

53496602

Analogs

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Popular Name: (2S)-N-(4-chloro-3-cyano-phenyl)tetrahydrofuran-2-carboxamide (2S)-N-(4-chloro-3-cyano-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	5.51	-16.6	1	4	0	62	250.685	2	↓ MOL2 SDF SMILES Flexibase

53496604

Analogs

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Popular Name: (2R)-N-(4-chloro-3-cyano-phenyl)tetrahydrofuran-2-carboxamide (2R)-N-(4-chloro-3-cyano-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	5.49	-17.05	1	4	0	62	250.685	2	↓ MOL2 SDF SMILES Flexibase

36158938

Analogs

36158940

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Popular Name: (2S)-N-(2-carbamothioyl-3-fluoro-phenyl)tetrahydrofuran-2-carboxamide (2S)-N-(2-carbamothioyl-3-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	4.03	-16.38	3	4	0	64	268.313	3	↓ MOL2 SDF SMILES Flexibase

36158940

Analogs

36158938

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Popular Name: (2R)-N-(2-carbamothioyl-3-fluoro-phenyl)tetrahydrofuran-2-carboxamide (2R)-N-(2-carbamothioyl-3-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	4.02	-17.72	3	4	0	64	268.313	3	↓ MOL2 SDF SMILES Flexibase

21145081

Analogs

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Popular Name: (2S)-N-[4-(tert-butylcarbamoyl)-3-methyl-phenyl]tetrahydrofuran-2-carboxamide (2S)-N-[4-(tert-butylcarbamoyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	5.71	-21.6	2	5	0	67	304.39	4	↓ MOL2 SDF SMILES Flexibase

21145083

Analogs

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Popular Name: (2R)-N-[4-(tert-butylcarbamoyl)-3-methyl-phenyl]tetrahydrofuran-2-carboxamide (2R)-N-[4-(tert-butylcarbamoyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	5.68	-16.55	2	5	0	67	304.39	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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