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Analogs

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Popular Name: 4-[(8-methylimidazo[1,2-a]pyridin-2-yl)methoxy]-N-[2-oxo-2-(prop-2-ynylamino)ethyl]benzamide 4-[(8-methylimidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 7.02 -15.87 2 7 0 85 376.416 7 ↓
Mid Mid (pH 6-8) 2.55 7.47 -35.87 3 7 1 86 377.424 7 ↓

Analogs

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Popular Name: (1S)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]propan-1-ol (1S)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 7.5 -10.59 1 4 0 47 282.343 5 ↓
Mid Mid (pH 6-8) 3.21 7.95 -29.87 2 4 1 48 283.351 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]propan-1-ol (1R)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 7.51 -10.56 1 4 0 47 282.343 5 ↓
Mid Mid (pH 6-8) 3.21 7.95 -29.84 2 4 1 48 283.351 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1S)-1-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1S)-1-[4-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.76 6.49 -11.2 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.76 7.03 -30.01 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1R)-1-[4-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.76 6.45 -11.17 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.76 6.99 -30.03 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1S)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1S)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 6.6 -10.9 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.71 7.14 -29.97 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1R)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 6.59 -10.91 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.71 7.13 -29.91 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1S)-1-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1S)-1-[3-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 6.49 -11.21 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.73 7.03 -29.92 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]ethanol (1R)-1-[3-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 6.45 -11.25 1 4 0 47 268.316 4 ↓
Mid Mid (pH 6-8) 2.73 6.98 -29.89 2 4 1 48 269.324 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1S)-1-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]propan-1-ol (1S)-1-[4-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.26 7.42 -10.67 1 4 0 47 282.343 5 ↓
Mid Mid (pH 6-8) 3.26 7.86 -29.88 2 4 1 48 283.351 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]propan-1-ol (1R)-1-[4-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.26 7.38 -10.78 1 4 0 47 282.343 5 ↓
Mid Mid (pH 6-8) 3.26 7.83 -29.86 2 4 1 48 283.351 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1R)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)-5-methyl-phenyl]ethanol (1R)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 7.25 -10.97 1 4 0 47 282.343 4 ↓
Mid Mid (pH 6-8) 3.13 7.7 -31.49 2 4 1 48 283.351 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1S)-1-[2-(imidazo[1,2-a]pyridin-2-ylmethoxy)-5-methyl-phenyl]ethanol (1S)-1-[2-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 7.26 -10.97 1 4 0 47 282.343 4 ↓
Mid Mid (pH 6-8) 3.13 7.71 -31.5 2 4 1 48 283.351 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzamidine 4-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.58 6.15 -41.52 4 5 1 78 267.312 4 ↓
Lo Low (pH 4.5-6) 1.58 6.57 -75.54 5 5 2 79 268.32 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzonitrile 3-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 8.71 -11.59 0 4 0 50 249.273 3 ↓
Lo Low (pH 4.5-6) 2.92 9.12 -36.53 1 4 1 52 250.281 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzamidine 2-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 6.56 -36.87 4 5 1 78 267.312 4 ↓
Lo Low (pH 4.5-6) 1.53 6.97 -80.38 5 5 2 79 268.32 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzenecarbothioamide 2-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 7.68 -20.84 2 4 0 53 283.356 4 ↓
Lo Low (pH 4.5-6) 2.94 8.09 -34.4 3 4 1 54 284.364 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzamidine 3-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 6.14 -41.52 4 5 1 78 267.312 4 ↓
Lo Low (pH 4.5-6) 1.55 6.55 -75.68 5 5 2 79 268.32 4 ↓

Analogs

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Popular Name: N-(2-acetamidoethyl)-3-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzamide N-(2-acetamidoethyl)-3-(imidazo[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 5.76 -20.41 2 7 0 85 352.394 7 ↓
Mid Mid (pH 6-8) 1.51 6.21 -40.29 3 7 1 86 353.402 7 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(imidazo[1,2-a]pyridin-2-ylmethoxy)-N-prop-2-ynyl-benzamide 3-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 7.91 -15.38 1 5 0 56 305.337 5 ↓
Mid Mid (pH 6-8) 2.52 8.36 -35.2 2 5 1 57 306.345 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-chloro-2-[(8-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide 5-chloro-2-[(8-methylimidazo[1,2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 7.45 -14.28 2 5 0 70 315.76 4 ↓
Mid Mid (pH 6-8) 3.57 7.9 -31.33 3 5 1 71 316.768 4 ↓

Analogs

31364747
31364747

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Popular Name: N-(3-isopropoxypropyl)-4-[(8-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N-(3-isopropoxypropyl)-4-[(8-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.78 9.59 -16.06 1 6 0 65 381.476 9 ↓
Mid Mid (pH 6-8) 3.78 10.01 -39.89 2 6 1 66 382.484 9 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-(imidazo[1,2-a]pyridin-2-ylmethoxy)-N-prop-2-ynyl-benzamide 4-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.54 7.93 -15.77 1 5 0 56 305.337 5 ↓
Lo Low (pH 4.5-6) 2.54 8.34 -40.96 2 5 1 57 306.345 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methoxy-2-[(8-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N-methoxy-2-[(8-methylimidazo[1,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 9.05 -21.42 1 6 0 65 311.341 5 ↓
Mid Mid (pH 6-8) 3.24 9.46 -35.29 2 6 1 66 312.349 5 ↓

Analogs

48303059
48303059

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Popular Name: [2-(imidazo[1,2-a]pyridin-2-ylmethoxy)-5-methoxy-phenyl]methanol [2-(imidazo[1,2-a]pyridin-2-ylme…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.51 5.14 -12.7 1 5 0 56 284.315 5 ↓
Mid Mid (pH 6-8) 2.51 5.58 -34.54 2 5 1 57 285.323 5 ↓

Analogs

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Popular Name: 2-[[2-(chloromethyl)-4-methoxy-phenoxy]methyl]imidazo[1,2-a]pyridine 2-[[2-(chloromethyl)-4-methoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.95 -10.79 0 4 0 36 302.761 5 ↓
Mid Mid (pH 6-8) 3.75 9.39 -31.58 1 4 1 37 303.769 5 ↓

Analogs

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Popular Name: 2-[[2-(bromomethyl)-4-methoxy-phenoxy]methyl]imidazo[1,2-a]pyridine 2-[[2-(bromomethyl)-4-methoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 9.05 -10.53 0 4 0 36 347.212 5 ↓
Mid Mid (pH 6-8) 3.88 9.49 -31.42 1 4 1 37 348.22 5 ↓

Analogs

8271931
8271931

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(imidazo[1,2-a]pyridin-2-ylmethoxy)-N-methyl-benzamide 2-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 7.8 -16.9 1 5 0 56 281.315 4 ↓
Mid Mid (pH 6-8) 2.88 8.24 -31.04 2 5 1 57 282.323 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(imidazo[1,2-a]pyridin-2-ylmethoxy)-N-[(1S)-2-methoxy-1-methyl-ethyl]benzamide 3-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 7.45 -15.18 1 6 0 65 339.395 7 ↓
Mid Mid (pH 6-8) 2.67 7.9 -34.75 2 6 1 66 340.403 7 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(imidazo[1,2-a]pyridin-2-ylmethoxy)-N-[(1R)-2-methoxy-1-methyl-ethyl]benzamide 3-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 7.45 -15.19 1 6 0 65 339.395 7 ↓
Mid Mid (pH 6-8) 2.67 7.9 -34.74 2 6 1 66 340.403 7 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methylamino]-N-methyl-propanamide (2S)-2-[[4-(imidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 6.07 -15.97 2 6 0 68 338.411 7 ↓
Mid Mid (pH 6-8) 2.19 6.51 -33.61 3 6 1 69 339.419 7 ↓
Mid Mid (pH 6-8) 2.19 7.32 -49.92 3 6 1 72 339.419 7 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methylamino]-N-methyl-propanamide (2R)-2-[[4-(imidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 6.15 -17.41 2 6 0 68 338.411 7 ↓
Mid Mid (pH 6-8) 2.19 7.32 -49.9 3 6 1 72 339.419 7 ↓
Mid Mid (pH 6-8) 2.19 6.6 -34.32 3 6 1 69 339.419 7 ↓

Analogs

25073327
25073327
25075377
25075377
25080753
25080753

Draw Identity 99% 90% 80% 70%

Popular Name: N,N-bis(2-methoxyethyl)-3-[(6-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N,N-bis(2-methoxyethyl)-3-[(6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 9.11 -15.41 0 7 0 65 397.475 10 ↓
Mid Mid (pH 6-8) 2.50 9.52 -35.99 1 7 1 67 398.483 10 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(6-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide 3-[(6-methylimidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 5.73 -15.85 2 5 0 70 281.315 4 ↓
Mid Mid (pH 6-8) 2.39 6.18 -35.2 3 5 1 71 282.323 4 ↓

Analogs

25073327
25073327
25075377
25075377

Draw Identity 99% 90% 80% 70%

Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.18 -14.39 1 7 0 82 353.378 7 ↓
Mid Mid (pH 6-8) 2.62 8.63 -34.49 2 7 1 83 354.386 7 ↓

Analogs

25075212
25075212

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Popular Name: N-[2-(diethylamino)-2-oxo-ethyl]-N-methyl-3-[(6-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N-[2-(diethylamino)-2-oxo-ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 11.56 -23.74 0 7 0 67 408.502 8 ↓
Mid Mid (pH 6-8) 2.64 12.01 -41.65 1 7 1 68 409.51 8 ↓

Analogs

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Popular Name: 4-(imidazo[1,2-a]pyridin-2-ylmethoxy)-2,5-dimethyl-aniline 4-(imidazo[1,2-a]pyridin-2-ylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 7.68 -10.61 2 4 0 53 267.332 3 ↓
Mid Mid (pH 6-8) 3.43 8.13 -28.31 3 4 1 54 268.34 3 ↓

Analogs

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Popular Name: (2S)-N-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]-2-methylsulfanyl-propanamide (2S)-N-[3-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 9.02 -18.9 1 5 0 56 341.436 6 ↓
Mid Mid (pH 6-8) 3.23 9.46 -34.7 2 5 1 57 342.444 6 ↓

Analogs

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Popular Name: (2R)-N-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]-2-methylsulfanyl-propanamide (2R)-N-[3-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 9.01 -18.93 1 5 0 56 341.436 6 ↓
Mid Mid (pH 6-8) 3.23 9.46 -34.76 2 5 1 57 342.444 6 ↓

Analogs

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Popular Name: N-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]acetamide N-[3-(imidazo[1,2-a]pyridin-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 7.21 -17.45 1 5 0 56 281.315 4 ↓
Mid Mid (pH 6-8) 2.39 7.64 -33.62 2 5 1 57 282.323 4 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.80 10.27 -13.97 0 5 0 53 296.326 5 ↓
Mid Mid (pH 6-8) 3.80 10.72 -29.45 1 5 1 54 297.334 5 ↓

Analogs

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Popular Name: N-[3-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]propanamide N-[3-(imidazo[1,2-a]pyridin-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 8.02 -17.02 1 5 0 56 295.342 5 ↓
Mid Mid (pH 6-8) 3.22 8.46 -33.27 2 5 1 57 296.35 5 ↓

Analogs

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Popular Name: 1-(3-hydroxypropyl)-3-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]urea 1-(3-hydroxypropyl)-3-[4-(imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 4.06 -17.73 3 7 0 88 340.383 7 ↓
Mid Mid (pH 6-8) 2.34 4.51 -35.12 4 7 1 89 341.391 7 ↓

Analogs

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Popular Name: 4-chloro-3-(imidazo[1,2-a]pyridin-2-ylmethoxy)aniline 4-chloro-3-(imidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 6.74 -10.51 2 4 0 53 273.723 3 ↓
Mid Mid (pH 6-8) 2.87 7.18 -29.4 3 4 1 54 274.731 3 ↓

Analogs

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Popular Name: 2-[(5-bromo-2-chloro-phenoxy)methyl]imidazo[1,2-a]pyridine 2-[(5-bromo-2-chloro-phenoxy)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.61 9.48 -8.84 0 3 0 27 337.604 3 ↓
Mid Mid (pH 6-8) 4.61 9.93 -28.54 1 3 1 28 338.612 3 ↓

Analogs

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Popular Name: N-(2-amino-2-oxo-ethyl)-2-[(8-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N-(2-amino-2-oxo-ethyl)-2-[(8-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 5.41 -17.82 3 7 0 99 338.367 6 ↓
Mid Mid (pH 6-8) 2.02 5.86 -33.23 4 7 1 100 339.375 6 ↓

Analogs

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Popular Name: N-(2-amino-2-oxo-ethyl)-3-[(6-methylimidazo[1,2-a]pyridin-2-yl)methoxy]benzamide N-(2-amino-2-oxo-ethyl)-3-[(6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 4.25 -16.65 3 7 0 99 338.367 6 ↓
Mid Mid (pH 6-8) 1.49 4.69 -36.54 4 7 1 100 339.375 6 ↓

Analogs

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Popular Name: 3-amino-4-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzonitrile 3-amino-4-(imidazo[1,2-a]pyridin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 6.71 -11.87 2 5 0 76 264.288 3 ↓
Mid Mid (pH 6-8) 2.36 7.15 -35.72 3 5 1 78 265.296 3 ↓

Analogs

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Popular Name: 3-chloro-4-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzenecarbothioamide 3-chloro-4-(imidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.60 8.1 -16.94 2 4 0 53 317.801 4 ↓
Mid Mid (pH 6-8) 3.60 8.54 -39.73 3 4 1 54 318.809 4 ↓

Analogs

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Popular Name: 3-chloro-4-(imidazo[1,2-a]pyridin-2-ylmethoxy)benzamidine 3-chloro-4-(imidazo[1,2-a]pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6.74 -41.23 4 5 1 78 301.757 4 ↓
Mid Mid (pH 6-8) 2.18 7.19 -75.61 5 5 2 79 302.765 4 ↓

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