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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(3-methoxyphenyl)-(1-methylindolin-5-yl)methanol (S)-(3-methoxyphenyl)-(1-methyli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.96 6.33 -7.57 1 3 0 33 269.344 3 ↓
Lo Low (pH 4.5-6) 2.96 6.92 -36.95 2 3 1 34 270.352 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(3-methoxyphenyl)-(1-methylindolin-5-yl)methanol (R)-(3-methoxyphenyl)-(1-methyli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.96 6.31 -7.47 1 3 0 33 269.344 3 ↓
Lo Low (pH 4.5-6) 2.96 6.92 -37 2 3 1 34 270.352 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(4-fluorophenyl)-(1-methylindolin-5-yl)methanol (R)-(4-fluorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.1 -6.7 1 2 0 23 257.308 2 ↓
Lo Low (pH 4.5-6) 3.09 7.69 -37.27 2 2 1 25 258.316 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(4-fluorophenyl)-(1-methylindolin-5-yl)methanol (S)-(4-fluorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.09 -6.66 1 2 0 23 257.308 2 ↓
Lo Low (pH 4.5-6) 3.09 7.7 -37.33 2 2 1 25 258.316 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(1-methylindolin-5-yl)-(m-tolyl)methanol (S)-(1-methylindolin-5-yl)-(m-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 7.7 -6.01 1 2 0 23 253.345 2 ↓
Lo Low (pH 4.5-6) 3.35 8.29 -35.43 2 2 1 25 254.353 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(1-methylindolin-5-yl)-(m-tolyl)methanol (R)-(1-methylindolin-5-yl)-(m-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 7.69 -6.02 1 2 0 23 253.345 2 ↓
Lo Low (pH 4.5-6) 3.35 8.29 -35.4 2 2 1 25 254.353 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2,3-dimethylphenyl)-(1-methylindolin-5-yl)methanol (R)-(2,3-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.73 7.99 -6.19 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.73 8.6 -35.85 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2,3-dimethylphenyl)-(1-methylindolin-5-yl)methanol (S)-(2,3-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.73 7.89 -6.14 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.73 8.5 -35.93 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2,3-dichlorophenyl)-(1-methylindolin-5-yl)methanol (S)-(2,3-dichlorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.19 7.79 -7.39 1 2 0 23 308.208 2 ↓
Lo Low (pH 4.5-6) 4.19 8.39 -37.29 2 2 1 25 309.216 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2,3-dichlorophenyl)-(1-methylindolin-5-yl)methanol (R)-(2,3-dichlorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.19 7.77 -7.36 1 2 0 23 308.208 2 ↓
Lo Low (pH 4.5-6) 4.19 8.37 -37.36 2 2 1 25 309.216 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2,5-dichlorophenyl)-(1-methylindolin-5-yl)methanol (S)-(2,5-dichlorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.21 7.84 -5.3 1 2 0 23 308.208 2 ↓
Lo Low (pH 4.5-6) 4.21 8.46 -35.42 2 2 1 25 309.216 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2,5-dichlorophenyl)-(1-methylindolin-5-yl)methanol (R)-(2,5-dichlorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.21 7.82 -5.35 1 2 0 23 308.208 2 ↓
Lo Low (pH 4.5-6) 4.21 8.42 -35.36 2 2 1 25 309.216 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(5-fluoro-2-methyl-phenyl)-(1-methylindolin-5-yl)methanol (R)-(5-fluoro-2-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.42 -6.54 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.02 -37.06 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(5-fluoro-2-methyl-phenyl)-(1-methylindolin-5-yl)methanol (S)-(5-fluoro-2-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.51 -6.62 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.13 -37.11 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2,5-difluorophenyl)-(1-methylindolin-5-yl)methanol (S)-(2,5-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.15 -6.09 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.75 -35.97 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2,5-difluorophenyl)-(1-methylindolin-5-yl)methanol (R)-(2,5-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.15 -6.08 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.74 -35.99 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(3,4-difluorophenyl)-(1-methylindolin-5-yl)methanol (S)-(3,4-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.15 -8.18 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.74 -39.63 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(3,4-difluorophenyl)-(1-methylindolin-5-yl)methanol (R)-(3,4-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.14 -8.11 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.76 -39.88 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(5-chloro-2-methoxy-phenyl)-(1-methylindolin-5-yl)methanol (S)-(5-chloro-2-methoxy-phenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 6.92 -6.63 1 3 0 33 303.789 3 ↓
Lo Low (pH 4.5-6) 3.59 7.51 -36.05 2 3 1 34 304.797 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(5-chloro-2-methoxy-phenyl)-(1-methylindolin-5-yl)methanol (R)-(5-chloro-2-methoxy-phenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 6.96 -6.68 1 3 0 33 303.789 3 ↓
Lo Low (pH 4.5-6) 3.59 7.56 -36.04 2 3 1 34 304.797 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(4-fluoro-2-methyl-phenyl)-(1-methylindolin-5-yl)methanol (R)-(4-fluoro-2-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.41 -6.61 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.02 -37.59 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(4-fluoro-2-methyl-phenyl)-(1-methylindolin-5-yl)methanol (S)-(4-fluoro-2-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.51 -6.67 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.13 -37.51 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2,4-difluorophenyl)-(1-methylindolin-5-yl)methanol (S)-(2,4-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.15 -6.97 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.75 -37.33 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2,4-difluorophenyl)-(1-methylindolin-5-yl)methanol (R)-(2,4-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.15 -6.9 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.74 -37.36 2 2 1 25 276.306 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(3,5-dimethylphenyl)-(1-methylindolin-5-yl)methanol (R)-(3,5-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.36 -6.06 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.95 -35.53 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(3,5-dimethylphenyl)-(1-methylindolin-5-yl)methanol (S)-(3,5-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.35 -6.12 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.94 -35.52 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(4-chlorophenyl)-(1-methylindolin-5-yl)methanol (R)-(4-chlorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 7.55 -6.03 1 2 0 23 273.763 2 ↓
Lo Low (pH 4.5-6) 3.61 8.14 -36.52 2 2 1 25 274.771 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(4-chlorophenyl)-(1-methylindolin-5-yl)methanol (S)-(4-chlorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 7.54 -6.03 1 2 0 23 273.763 2 ↓
Lo Low (pH 4.5-6) 3.61 8.16 -36.53 2 2 1 25 274.771 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(3,4-dimethylphenyl)-(1-methylindolin-5-yl)methanol (S)-(3,4-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.25 -6.09 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.87 -35.43 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(3,4-dimethylphenyl)-(1-methylindolin-5-yl)methanol (R)-(3,4-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.24 -6.14 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.83 -35.38 2 2 1 25 268.38 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(2-fluoro-5-methyl-phenyl)-(1-methylindolin-5-yl)methanol (R)-(2-fluoro-5-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.75 -7.03 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.34 -36.17 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(2-fluoro-5-methyl-phenyl)-(1-methylindolin-5-yl)methanol (S)-(2-fluoro-5-methyl-phenyl)-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 7.75 -7.05 1 2 0 23 271.335 2 ↓
Lo Low (pH 4.5-6) 3.47 8.36 -36.21 2 2 1 25 272.343 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(4-isopropylphenyl)-(1-methylindolin-5-yl)methanol (S)-(4-isopropylphenyl)-(1-methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.44 8.96 -5.69 1 2 0 23 281.399 3 ↓
Lo Low (pH 4.5-6) 4.44 9.56 -35.09 2 2 1 25 282.407 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(4-isopropylphenyl)-(1-methylindolin-5-yl)methanol (R)-(4-isopropylphenyl)-(1-methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.44 8.95 -5.7 1 2 0 23 281.399 3 ↓
Lo Low (pH 4.5-6) 4.44 9.56 -35.07 2 2 1 25 282.407 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(1-methylindolin-5-yl)-(p-tolyl)methanol (S)-(1-methylindolin-5-yl)-(p-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 7.71 -6.02 1 2 0 23 253.345 2 ↓
Lo Low (pH 4.5-6) 3.38 8.32 -35.4 2 2 1 25 254.353 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (R)-(1-methylindolin-5-yl)-(p-tolyl)methanol (R)-(1-methylindolin-5-yl)-(p-to…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 7.7 -6.03 1 2 0 23 253.345 2 ↓
Lo Low (pH 4.5-6) 3.38 8.28 -35.3 2 2 1 25 254.353 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (S)-(1-methylindolin-5-yl)-(4-propylphenyl)methanol (S)-(1-methylindolin-5-yl)-(4-pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.23 9.25 -5.7 1 2 0 23 281.399 4 ↓
Lo Low (pH 4.5-6) 4.23 9.85 -35.18 2 2 1 25 282.407 4 ↓

Analogs

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Popular Name: (R)-(1-methylindolin-5-yl)-(4-propylphenyl)methanol (R)-(1-methylindolin-5-yl)-(4-pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.23 9.24 -5.63 1 2 0 23 281.399 4 ↓
Lo Low (pH 4.5-6) 4.23 9.85 -35.1 2 2 1 25 282.407 4 ↓

Analogs

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Popular Name: (S)-(2-chlorophenyl)-(1-methylindolin-5-yl)methanol (S)-(2-chlorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 7.33 -6.54 1 2 0 23 273.763 2 ↓
Lo Low (pH 4.5-6) 3.56 7.93 -35.84 2 2 1 25 274.771 2 ↓

Analogs

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Popular Name: (R)-(2-chlorophenyl)-(1-methylindolin-5-yl)methanol (R)-(2-chlorophenyl)-(1-methylin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 7.31 -6.54 1 2 0 23 273.763 2 ↓
Lo Low (pH 4.5-6) 3.56 7.93 -35.84 2 2 1 25 274.771 2 ↓

Analogs

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Popular Name: (R)-(1-methylindolin-5-yl)-phenyl-methanol (R)-(1-methylindolin-5-yl)-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 7.03 -6.01 1 2 0 23 239.318 2 ↓
Lo Low (pH 4.5-6) 2.93 7.64 -35.37 2 2 1 25 240.326 2 ↓

Analogs

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Popular Name: (S)-(1-methylindolin-5-yl)-phenyl-methanol (S)-(1-methylindolin-5-yl)-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 7.02 -6 1 2 0 23 239.318 2 ↓
Lo Low (pH 4.5-6) 2.93 7.64 -35.37 2 2 1 25 240.326 2 ↓

Analogs

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Popular Name: (R)-(4-methoxyphenyl)-(1-methylindolin-5-yl)methanol (R)-(4-methoxyphenyl)-(1-methyli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 6.33 -7.4 1 3 0 33 269.344 3 ↓
Lo Low (pH 4.5-6) 2.98 6.94 -37.08 2 3 1 34 270.352 3 ↓

Analogs

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Popular Name: (S)-(4-methoxyphenyl)-(1-methylindolin-5-yl)methanol (S)-(4-methoxyphenyl)-(1-methyli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 6.32 -7.42 1 3 0 33 269.344 3 ↓
Lo Low (pH 4.5-6) 2.98 6.9 -37.06 2 3 1 34 270.352 3 ↓

Analogs

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Popular Name: (R)-(2,5-dimethylphenyl)-(1-methylindolin-5-yl)methanol (R)-(2,5-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.09 -6.07 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.68 -35.73 2 2 1 25 268.38 2 ↓

Analogs

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Popular Name: (S)-(2,5-dimethylphenyl)-(1-methylindolin-5-yl)methanol (S)-(2,5-dimethylphenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.75 8.01 -6.04 1 2 0 23 267.372 2 ↓
Lo Low (pH 4.5-6) 3.75 8.63 -35.88 2 2 1 25 268.38 2 ↓

Analogs

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Popular Name: (S)-(4-ethylphenyl)-(1-methylindolin-5-yl)methanol (S)-(4-ethylphenyl)-(1-methylind…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.84 8.48 -5.82 1 2 0 23 267.372 3 ↓
Lo Low (pH 4.5-6) 3.84 9.07 -35.24 2 2 1 25 268.38 3 ↓

Analogs

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Popular Name: (R)-(4-ethylphenyl)-(1-methylindolin-5-yl)methanol (R)-(4-ethylphenyl)-(1-methylind…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.84 8.46 -5.81 1 2 0 23 267.372 3 ↓
Lo Low (pH 4.5-6) 3.84 9.07 -35.23 2 2 1 25 268.38 3 ↓

Analogs

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Popular Name: (S)-(3,5-difluorophenyl)-(1-methylindolin-5-yl)methanol (S)-(3,5-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.17 -6.1 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.78 -37.05 2 2 1 25 276.306 2 ↓

Analogs

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Popular Name: (R)-(3,5-difluorophenyl)-(1-methylindolin-5-yl)methanol (R)-(3,5-difluorophenyl)-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 7.16 -6.04 1 2 0 23 275.298 2 ↓
Lo Low (pH 4.5-6) 3.18 7.77 -37.02 2 2 1 25 276.306 2 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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