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Popular Name: N-(3-thienylmethyl)pyrazin-2-amine N-(3-thienylmethyl)pyrazin-2-amine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 3.25 -5.68 1 3 0 38 191.259 3 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(3-thienyl)ethyl]amino]pyrazine-2-carbonitrile 3-[[(1S)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 4.76 -8.17 1 4 0 62 230.296 3 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(3-thienyl)ethyl]amino]pyrazine-2-carbonitrile 3-[[(1R)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 4.75 -8.19 1 4 0 62 230.296 3 ↓

Analogs

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Popular Name: N-[(1S)-1-(3-thienyl)ethyl]pyrazin-2-amine N-[(1S)-1-(3-thienyl)ethyl]pyraz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 4 -5.68 1 3 0 38 205.286 3 ↓

Analogs

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Popular Name: N-[(1R)-1-(3-thienyl)ethyl]pyrazin-2-amine N-[(1R)-1-(3-thienyl)ethyl]pyraz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 3.99 -5.67 1 3 0 38 205.286 3 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(3-thienyl)ethyl]amino]pyrazine-2-carbothioamide 3-[[(1S)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 3.61 -12.84 3 4 0 64 264.379 4 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(3-thienyl)ethyl]amino]pyrazine-2-carbothioamide 3-[[(1R)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 3.63 -13.76 3 4 0 64 264.379 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-1-(3-thienyl)ethyl]pyrazin-2-amine 6-chloro-N-[(1S)-1-(3-thienyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 4.42 -4.98 1 3 0 38 239.731 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-(3-thienyl)ethyl]pyrazin-2-amine 6-chloro-N-[(1R)-1-(3-thienyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 4.41 -4.96 1 3 0 38 239.731 3 ↓

Analogs

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Popular Name: 3-chloro-N-[(1S)-1-(3-thienyl)ethyl]pyrazin-2-amine 3-chloro-N-[(1S)-1-(3-thienyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 4.92 -5.89 1 3 0 38 239.731 3 ↓

Analogs

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Popular Name: 3-chloro-N-[(1R)-1-(3-thienyl)ethyl]pyrazin-2-amine 3-chloro-N-[(1R)-1-(3-thienyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 4.92 -5.89 1 3 0 38 239.731 3 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(3-thienyl)ethyl]amino]pyrazine-2-carboxylic 3-[[(1S)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.24 -51.3 1 5 -1 78 248.287 4 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(3-thienyl)ethyl]amino]pyrazine-2-carboxylic 3-[[(1R)-1-(3-thienyl)ethyl]amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.24 -51.17 1 5 -1 78 248.287 4 ↓

Analogs

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Popular Name: 6-chloro-N-methyl-N-(3-thienylmethyl)pyrazin-2-amine 6-chloro-N-methyl-N-(3-thienylme…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 5.86 -5.74 0 3 0 29 239.731 3 ↓

Analogs

42249805
42249805

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Popular Name: N-[(1R)-1-(2,5-dimethyl-3-thienyl)ethyl]pyrazin-2-amine N-[(1R)-1-(2,5-dimethyl-3-thieny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 5.57 -6.22 1 3 0 38 233.34 3 ↓

Analogs

42249800
42249800

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Popular Name: N-[(1S)-1-(2,5-dimethyl-3-thienyl)ethyl]pyrazin-2-amine N-[(1S)-1-(2,5-dimethyl-3-thieny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 5.59 -6.25 1 3 0 38 233.34 3 ↓

Parameters Provided:

ring.id = 179377
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 179377 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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