ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

35623909

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-1-morpholinosulfonylpiperidin-3-ol (3S)-1-morpholinosulfonylpiperid…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.67	-2.27	-9.92	1	6	0	70	250.32	2	↓ MOL2 SDF SMILES Flexibase

35623911

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-1-morpholinosulfonylpiperidin-3-ol (3R)-1-morpholinosulfonylpiperid…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.67	-2.12	-9.71	1	6	0	70	250.32	2	↓ MOL2 SDF SMILES Flexibase

36753809

Analogs

44906934
44906937
48411822
48411823
48411824

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonylpiperidin-4-amine 1-[(2S,6R)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.44	-0.17	-58.39	3	6	1	77	278.398	2	↓ MOL2 SDF SMILES Flexibase

36753811

Analogs

44906934
44906937
48411822
48411823
48411824

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonylpiperidin-4-amine 1-[(2S,6S)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.44	0.07	-56.03	3	6	1	77	278.398	2	↓ MOL2 SDF SMILES Flexibase

36753813

Analogs

44906934
44906937
48411822
48411823
48411824

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonylpiperidin-4-amine 1-[(2R,6R)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.44	-0.02	-53.97	3	6	1	77	278.398	2	↓ MOL2 SDF SMILES Flexibase

57994989

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-methanesulfonamide N-[1-[(2S,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.09	0.44	-16.55	0	8	0	87	369.509	4	↓ MOL2 SDF SMILES Flexibase

57994992

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-methanesulfonamide N-[1-[(2S,6S)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.09	0.43	-16.59	0	8	0	87	369.509	4	↓ MOL2 SDF SMILES Flexibase

57994993

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-methanesulfonamide N-[1-[(2R,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.09	0.43	-16.62	0	8	0	87	369.509	4	↓ MOL2 SDF SMILES Flexibase

62842945

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-methyl-1-morpholinosulfonyl-piperidine-4-carboxylic 4-methyl-1-morpholinosulfonyl-pi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.17	1.9	-47.47	0	7	-1	90	291.349	3	↓ MOL2 SDF SMILES Flexibase

62843068

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-methyl-piperidine-4-carboxylic 1-[(2S,6R)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.56	-52.44	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62843069

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-methyl-piperidine-4-carboxylic 1-[(2S,6S)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.56	-52.48	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62843070

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-methyl-piperidine-4-carboxylic 1-[(2R,6R)-2,6-dimethylmorpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.56	-52.43	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62845222

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-ethyl-1-morpholinosulfonyl-piperidine-4-carboxylic 4-ethyl-1-morpholinosulfonyl-pip…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.16	2.38	-46.47	0	7	-1	90	305.376	4	↓ MOL2 SDF SMILES Flexibase

62845286

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-morpholinosulfonyl-4-propyl-piperidine-4-carboxylic 1-morpholinosulfonyl-4-propyl-pi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.72	3.15	-46.8	0	7	-1	90	319.403	5	↓ MOL2 SDF SMILES Flexibase

62872940

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-3-methyl-1-morpholinosulfonyl-piperidine-3-carboxylic (3S)-3-methyl-1-morpholinosulfon…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.17	2.36	-48.82	0	7	-1	90	291.349	3	↓ MOL2 SDF SMILES Flexibase

62872941

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-methyl-1-morpholinosulfonyl-piperidine-3-carboxylic (3R)-3-methyl-1-morpholinosulfon…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.17	2.39	-48.73	0	7	-1	90	291.349	3	↓ MOL2 SDF SMILES Flexibase

62873067

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-3-methyl-piperidine-3-carboxylic (3R)-1-[(2S,6R)-2,6-dimethylmorp…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.88	-48.37	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62873068

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-3-methyl-piperidine-3-carboxylic (3R)-1-[(2S,6S)-2,6-dimethylmorp…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.87	-48.56	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62873069

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-3-methyl-piperidine-3-carboxylic (3R)-1-[(2R,6R)-2,6-dimethylmorp…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.87	-48.43	0	7	-1	90	319.403	3	↓ MOL2 SDF SMILES Flexibase

62873452

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-3-ethyl-1-morpholinosulfonyl-piperidine-3-carboxylic (3S)-3-ethyl-1-morpholinosulfony…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.16	2.86	-47.88	0	7	-1	90	305.376	4	↓ MOL2 SDF SMILES Flexibase

62873453

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-ethyl-1-morpholinosulfonyl-piperidine-3-carboxylic (3R)-3-ethyl-1-morpholinosulfony…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.16	2.84	-47.99	0	7	-1	90	305.376	4	↓ MOL2 SDF SMILES Flexibase

62873817

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-1-morpholinosulfonyl-3-propyl-piperidine-3-carboxylic (3S)-1-morpholinosulfonyl-3-prop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.72	3.61	-48.27	0	7	-1	90	319.403	5	↓ MOL2 SDF SMILES Flexibase

62873818

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-1-morpholinosulfonyl-3-propyl-piperidine-3-carboxylic (3R)-1-morpholinosulfonyl-3-prop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.72	3.61	-48.33	0	7	-1	90	319.403	5	↓ MOL2 SDF SMILES Flexibase

65539483

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S,6R)-2,6-dimethyl-4-(1-piperidylsulfonyl)morpholine (2S,6R)-2,6-dimethyl-4-(1-piperi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.20	2.61	-7.75	0	5	0	50	262.375	2	↓ MOL2 SDF SMILES Flexibase

65539485

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S,6S)-2,6-dimethyl-4-(1-piperidylsulfonyl)morpholine (2S,6S)-2,6-dimethyl-4-(1-piperi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.20	2.84	-7.47	0	5	0	50	262.375	2	↓ MOL2 SDF SMILES Flexibase

65539489

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R,6R)-2,6-dimethyl-4-(1-piperidylsulfonyl)morpholine (2R,6R)-2,6-dimethyl-4-(1-piperi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.20	2.85	-7.49	0	5	0	50	262.375	2	↓ MOL2 SDF SMILES Flexibase

65576034

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S,6R)-2,6-dimethyl-4-[[(2R)-2-methyl-1-piperidyl]sulfonyl]morpholine (2S,6R)-2,6-dimethyl-4-[[(2R)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.53	3.28	-7.74	0	5	0	50	276.402	2	↓ MOL2 SDF SMILES Flexibase

65576036

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S,6R)-2,6-dimethyl-4-[[(2S)-2-methyl-1-piperidyl]sulfonyl]morpholine (2S,6R)-2,6-dimethyl-4-[[(2S)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.53	3.32	-7.65	0	5	0	50	276.402	2	↓ MOL2 SDF SMILES Flexibase

70187974

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]ethanamine 2-[1-[(2S,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.32	1.21	-55.14	3	6	1	77	306.452	4	↓ MOL2 SDF SMILES Flexibase

70187975

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]ethanamine 2-[1-[(2S,6S)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.32	1.36	-52.74	3	6	1	77	306.452	4	↓ MOL2 SDF SMILES Flexibase

70187976

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]ethanamine 2-[1-[(2R,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.32	1.36	-52.79	3	6	1	77	306.452	4	↓ MOL2 SDF SMILES Flexibase

70188085

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(1-morpholinosulfonyl-4-piperidyl)ethanamine 2-(1-morpholinosulfonyl-4-piperi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.40	-0.14	-52.78	3	6	1	77	278.398	4	↓ MOL2 SDF SMILES Flexibase

70189507

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-ethanamine 2-[1-[(2S,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.30	3.25	-47.95	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

70189508

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-ethanamine 2-[1-[(2S,6S)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.30	3.24	-48.03	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

70189509

Analogs

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Popular Name: 2-[1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-4-piperidyl]-N-methyl-ethanamine 2-[1-[(2R,6R)-2,6-dimethylmorpho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.30	3.32	-49.16	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

70189594

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-2-(1-morpholinosulfonyl-4-piperidyl)ethanamine N-methyl-2-(1-morpholinosulfonyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.58	1.73	-48.21	2	6	1	66	292.425	5	↓ MOL2 SDF SMILES Flexibase

70192251

Analogs

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Popular Name: N-methyl-2-[(2S)-1-morpholinosulfonyl-2-piperidyl]ethanamine N-methyl-2-[(2S)-1-morpholinosul…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.52	1.45	-48	2	6	1	66	292.425	5	↓ MOL2 SDF SMILES Flexibase

70192253

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-methyl-2-[(2R)-1-morpholinosulfonyl-2-piperidyl]ethanamine N-methyl-2-[(2R)-1-morpholinosul…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.52	1.62	-47.58	2	6	1	66	292.425	5	↓ MOL2 SDF SMILES Flexibase

70192400

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(2R)-1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-2-piperidyl]-N-methyl-ethanamine 2-[(2R)-1-[(2S,6R)-2,6-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	3.13	-48.52	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

70192402

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(2R)-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-2-piperidyl]-N-methyl-ethanamine 2-[(2R)-1-[(2S,6S)-2,6-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	3.08	-48.74	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

70192403

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(2R)-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]sulfonyl-2-piperidyl]-N-methyl-ethanamine 2-[(2R)-1-[(2R,6R)-2,6-dimethylm…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	2.85	-48.2	2	6	1	66	320.479	5	↓ MOL2 SDF SMILES Flexibase

48945885

Analogs

42584388
42584391

Draw Identity 99% 90% 80% 70%

Popular Name: 1-(3,3-dimethylmorpholin-4-yl)sulfonylpiperidine-4-carboxylic 1-(3,3-dimethylmorpholin-4-yl)su…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.40	3.02	-51.4	0	7	-1	90	305.376	3	↓ MOL2 SDF SMILES Flexibase

48945887

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-1-(3,3-dimethylmorpholin-4-yl)sulfonylpiperidine-3-carboxylic (3S)-1-(3,3-dimethylmorpholin-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.40	2.77	-47.62	0	7	-1	90	305.376	3	↓ MOL2 SDF SMILES Flexibase

48945889

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-1-(3,3-dimethylmorpholin-4-yl)sulfonylpiperidine-2-carboxylic (2R)-1-(3,3-dimethylmorpholin-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.94	3.64	-47.63	0	7	-1	90	305.376	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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