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ZINC Item

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51482500

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(3-bromophenyl)methylsulfonyl]-N-[3-(hydroxymethyl)phenyl]acetamide 2-[(3-bromophenyl)methylsulfonyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	3.1	-30.06	2	5	0	83	398.278	6	↓ MOL2 SDF SMILES Flexibase

52436914

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(4-ethylphenyl)propanamide (2R)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.00	7.14	-27.53	1	5	0	72	397.443	8	↓ MOL2 SDF SMILES Flexibase

52436915

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(4-ethylphenyl)propanamide (2S)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.00	6.93	-28.41	1	5	0	72	397.443	8	↓ MOL2 SDF SMILES Flexibase

52437011

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(2,4-difluorophenyl)acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.98	4.91	-25.88	1	5	0	72	391.342	7	↓ MOL2 SDF SMILES Flexibase

52437025

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3,5-dimethylphenyl)propanamide (2R)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	7.04	-27.64	1	5	0	72	397.443	7	↓ MOL2 SDF SMILES Flexibase

52437026

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3,5-dimethylphenyl)propanamide (2S)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	6.83	-28.62	1	5	0	72	397.443	7	↓ MOL2 SDF SMILES Flexibase

52437055

Analogs

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Popular Name: N-(3-cyanophenyl)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]acetamide N-(3-cyanophenyl)-2-[[4-(difluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	5.13	-35.03	1	6	0	96	380.372	7	↓ MOL2 SDF SMILES Flexibase

52437101

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3,4-dimethylphenyl)propanamide (2R)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	6.93	-27.71	1	5	0	72	397.443	7	↓ MOL2 SDF SMILES Flexibase

52437102

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3,4-dimethylphenyl)propanamide (2S)-2-[[4-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	6.72	-28.7	1	5	0	72	397.443	7	↓ MOL2 SDF SMILES Flexibase

52437158

Analogs

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Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3-isopropylphenyl)acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.21	6.65	-28.74	1	5	0	72	397.443	8	↓ MOL2 SDF SMILES Flexibase

52437275

Analogs

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Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(3-fluorophenyl)acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.87	4.81	-28.08	1	5	0	72	373.352	7	↓ MOL2 SDF SMILES Flexibase

52437280

Analogs

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Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(2-ethyl-6-methyl-phenyl)acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	7.24	-28.82	1	5	0	72	397.443	8	↓ MOL2 SDF SMILES Flexibase

52437291

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-(2,5-difluorophenyl)acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.98	4.91	-28.53	1	5	0	72	391.342	7	↓ MOL2 SDF SMILES Flexibase

52437327

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-chlorophenyl)-2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]acetamide N-(4-chlorophenyl)-2-[[4-(difluo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	5.26	-29.3	1	5	0	72	389.807	7	↓ MOL2 SDF SMILES Flexibase

52437338

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[4-(difluoromethoxy)phenyl]methylsulfonyl]-N-methyl-N-phenyl-acetamide 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.97	6.52	-30.25	0	5	0	64	369.389	7	↓ MOL2 SDF SMILES Flexibase

52437402

Analogs

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Popular Name: 3-[[2-(3,4-dimethylanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(3,4-dimethylanilino)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	6.2	-34.92	1	6	0	84	388.489	6	↓ MOL2 SDF SMILES Flexibase

52437507

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(2,4-difluoroanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(2,4-difluoroanilino)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.31	5.17	-30.98	1	6	0	84	396.415	6	↓ MOL2 SDF SMILES Flexibase

52437511

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(2,3-dimethylanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(2,3-dimethylanilino)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.86	6.41	-34.86	1	6	0	84	388.489	6	↓ MOL2 SDF SMILES Flexibase

52437612

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2-anilino-2-oxo-ethyl)sulfonylmethyl]-N,N-dimethyl-benzamide 3-[(2-anilino-2-oxo-ethyl)sulfon…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.05	5.02	-35	1	6	0	84	360.435	6	↓ MOL2 SDF SMILES Flexibase

52437897

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(3-fluoroanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(3-fluoroanilino)-2-oxo-et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.19	5.07	-38.4	1	6	0	84	378.425	6	↓ MOL2 SDF SMILES Flexibase

52437923

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(2,5-difluoroanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(2,5-difluoroanilino)-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.31	5.21	-33.76	1	6	0	84	396.415	6	↓ MOL2 SDF SMILES Flexibase

52438000

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(4-chloroanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(4-chloroanilino)-2-oxo-et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.73	5.54	-34.64	1	6	0	84	394.88	6	↓ MOL2 SDF SMILES Flexibase

52438047

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-(3-chloroanilino)-2-oxo-ethyl]sulfonylmethyl]-N,N-dimethyl-benzamide 3-[[2-(3-chloroanilino)-2-oxo-et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.71	5.52	-37.04	1	6	0	84	394.88	6	↓ MOL2 SDF SMILES Flexibase

68887900

Analogs

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Popular Name: (2S)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3-fluorophenyl)propanamide (2S)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	6.91	-25.71	1	4	0	63	369.845	5	↓ MOL2 SDF SMILES Flexibase

68887901

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3-fluorophenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	7.57	-20.87	1	4	0	63	369.845	5	↓ MOL2 SDF SMILES Flexibase

68887902

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3-fluorophenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	7.28	-27.17	1	4	0	63	369.845	5	↓ MOL2 SDF SMILES Flexibase

68887997

Analogs

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3,4-difluorophenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.12	-29.44	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68887998

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3,4-difluorophenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.63	-22.6	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68887999

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3,4-difluorophenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.34	-28.19	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68888002

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,6-dimethylphenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	8.74	-16.19	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888003

Analogs

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Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,6-dimethylphenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	9.14	-24.13	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888004

Analogs

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Popular Name: (2S)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,6-dimethylphenyl)propanamide (2S)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	8.5	-20.88	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888021

Analogs

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Popular Name: 2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-phenyl-acetamide 2-[(1S)-1-(4-chlorophenyl)ethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.15	6.25	-25.5	1	4	0	63	337.828	5	↓ MOL2 SDF SMILES Flexibase

68888023

Analogs

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Popular Name: 2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-phenyl-acetamide 2-[(1R)-1-(4-chlorophenyl)ethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.15	6.25	-25.35	1	4	0	63	337.828	5	↓ MOL2 SDF SMILES Flexibase

68888030

Analogs

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Popular Name: 2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(3-methoxyphenyl)acetamide 2-[(1S)-1-(4-chlorophenyl)ethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.19	5.55	-29.36	1	5	0	72	367.854	6	↓ MOL2 SDF SMILES Flexibase

68888031

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-acetamide N-(3-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.18	7.53	-23.95	1	4	0	63	386.3	5	↓ MOL2 SDF SMILES Flexibase

68888040

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,5-dimethylphenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.74	-16.31	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888043

Analogs

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,5-dimethylphenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.51	-25.15	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888045

Analogs

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Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,5-dimethylphenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.72	-24.28	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888047

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-dimethylphenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.56	-24.88	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888048

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Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-dimethylphenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.77	-24.66	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888049

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Popular Name: (2S)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-dimethylphenyl)propanamide (2S)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	8.81	-21.71	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888070

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2-methoxy-5-methyl-phenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	7.32	-15.13	1	5	0	72	395.908	6	↓ MOL2 SDF SMILES Flexibase

68888071

Analogs

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2-methoxy-5-methyl-phenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	7.09	-23.88	1	5	0	72	395.908	6	↓ MOL2 SDF SMILES Flexibase

68888072

Analogs

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Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2-methoxy-5-methyl-phenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	7.29	-23.39	1	5	0	72	395.908	6	↓ MOL2 SDF SMILES Flexibase

68888073

Analogs

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-difluorophenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.17	-20.8	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68888074

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-difluorophenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.46	-13.6	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68888077

Analogs

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Popular Name: (2R)-2-[(1R)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,4-difluorophenyl)propanamide (2R)-2-[(1R)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	7.39	-20.78	1	4	0	63	387.835	5	↓ MOL2 SDF SMILES Flexibase

68888101

Analogs

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Popular Name: (2R)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,3-dimethylphenyl)propanamide (2R)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	8.63	-16.41	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

68888102

Analogs

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Popular Name: (2S)-2-[(1S)-1-(4-chlorophenyl)ethyl]sulfonyl-N-(2,3-dimethylphenyl)propanamide (2S)-2-[(1S)-1-(4-chlorophenyl)e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	8.4	-25.2	1	4	0	63	379.909	5	↓ MOL2 SDF SMILES Flexibase

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SQL Query Was

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