ZINC 12

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ZINC Item

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51482512

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-[3-(hydroxymethyl)phenyl]acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.94	3.24	-19.77	2	5	0	71	292.36	4	↓ MOL2 SDF SMILES Flexibase

36969070

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-methyl-3-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 4-methyl-3-[[2-(4-methyl-2-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.70	6.67	-74.95	1	6	-1	91	305.335	4	↓ MOL2 SDF SMILES Flexibase

36977875

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-chloro-2-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 5-chloro-2-[[2-(4-methyl-2-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.11	6.62	-44.58	1	6	-1	91	325.753	4	↓ MOL2 SDF SMILES Flexibase

36977960

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-methyl-2-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 3-methyl-2-[[2-(4-methyl-2-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	6.9	-50.07	1	6	-1	91	305.335	4	↓ MOL2 SDF SMILES Flexibase

62824098

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-iodo-2-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 5-iodo-2-[[2-(4-methyl-2-oxo-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	7.2	-44.68	1	6	-1	91	417.204	4	↓ MOL2 SDF SMILES Flexibase

62826485

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-bromo-2-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 3-bromo-2-[[2-(4-methyl-2-oxo-th…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.82	-46.8	1	6	-1	91	370.204	4	↓ MOL2 SDF SMILES Flexibase

63009023

Analogs

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Popular Name: 3-fluoro-4-[[2-(4-methyl-2-oxo-thiazol-3-yl)acetyl]amino]benzoic 3-fluoro-4-[[2-(4-methyl-2-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.41	5.84	-55.86	1	6	-1	91	309.298	4	↓ MOL2 SDF SMILES Flexibase

55107036

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(3-methylsulfanylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.04	6.93	-20.04	1	4	0	51	308.428	4	↓ MOL2 SDF SMILES Flexibase

69811152

Analogs

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Popular Name: N-(2-chloro-5-nitro-phenyl)-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(2-chloro-5-nitro-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.97	6.53	-19.84	1	7	0	97	327.749	4	↓ MOL2 SDF SMILES Flexibase

48791330

Analogs

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Popular Name: N-(3-fluoro-4-methoxy-phenyl)-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(3-fluoro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	4.55	-22.26	1	5	0	60	296.323	4	↓ MOL2 SDF SMILES Flexibase

48927604

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(4-fluoro-2-methyl-phenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.17	6.91	-16.89	1	4	0	51	294.351	3	↓ MOL2 SDF SMILES Flexibase

48927800

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(4-methylsulfanylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.06	6.93	-16.69	1	4	0	51	308.428	4	↓ MOL2 SDF SMILES Flexibase

48927813

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-chloro-2-methyl-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.68	7.35	-16.29	1	4	0	51	310.806	3	↓ MOL2 SDF SMILES Flexibase

48927909

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(2-methylsulfanylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.02	7.06	-15.21	1	4	0	51	308.428	4	↓ MOL2 SDF SMILES Flexibase

48928006

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(2,4-dimethylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	7.51	-16.85	1	4	0	51	290.388	3	↓ MOL2 SDF SMILES Flexibase

48935214

Analogs

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Popular Name: N-(2-chloro-4-iodo-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2-chloro-4-iodo-phenyl)-2-(4,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.32	7.63	-12.48	1	4	0	51	422.675	3	↓ MOL2 SDF SMILES Flexibase

48938394

Analogs

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Popular Name: N-(5-bromo-2-methyl-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(5-bromo-2-methyl-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.82	7.46	-18.17	1	4	0	51	355.257	3	↓ MOL2 SDF SMILES Flexibase

48940458

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(4-fluorophenyl)-N-methyl-acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.04	7.66	-17.17	0	4	0	42	294.351	3	↓ MOL2 SDF SMILES Flexibase

48947671

Analogs

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Popular Name: N-(3-chloro-2-methoxy-phenyl)-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(3-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	5.26	-14.3	1	5	0	60	312.778	4	↓ MOL2 SDF SMILES Flexibase

48963819

Analogs

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Popular Name: N-(2-bromophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2-bromophenyl)-2-(4,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.39	6.67	-13.72	1	4	0	51	341.23	3	↓ MOL2 SDF SMILES Flexibase

48963851

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(3,4-dimethylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	7.18	-16.84	1	4	0	51	290.388	3	↓ MOL2 SDF SMILES Flexibase

48963854

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(4-fluorophenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.79	5.98	-16.97	1	4	0	51	280.324	3	↓ MOL2 SDF SMILES Flexibase

48963904

Analogs

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Popular Name: N-(3,4-dichlorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(3,4-dichlorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	6.89	-18.48	1	4	0	51	331.224	3	↓ MOL2 SDF SMILES Flexibase

48963945

Analogs

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Popular Name: N-(2,5-dichlorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2,5-dichlorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	7.06	-14.54	1	4	0	51	331.224	3	↓ MOL2 SDF SMILES Flexibase

48963992

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(2-iodophenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.67	7.16	-13.29	1	4	0	51	388.23	3	↓ MOL2 SDF SMILES Flexibase

48964099

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(3-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.66	7.23	-15.06	1	4	0	51	310.806	3	↓ MOL2 SDF SMILES Flexibase

48964118

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(4-iodo-2-methyl-phenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	7.93	-16.04	1	4	0	51	402.257	3	↓ MOL2 SDF SMILES Flexibase

48964127

Analogs

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Popular Name: N-(3,5-dichlorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(3,5-dichlorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	6.94	-15.74	1	4	0	51	331.224	3	↓ MOL2 SDF SMILES Flexibase

48964214

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2-chloro-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.68	7.25	-13.76	1	4	0	51	310.806	3	↓ MOL2 SDF SMILES Flexibase

48964311

Analogs

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Popular Name: N-(4-cyanophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-cyanophenyl)-2-(4,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.39	6.31	-19.15	1	5	0	75	287.344	3	↓ MOL2 SDF SMILES Flexibase

48964369

Analogs

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Popular Name: N-(2,5-difluorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2,5-difluorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.89	6.08	-15.69	1	4	0	51	298.314	3	↓ MOL2 SDF SMILES Flexibase

48964414

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-bromo-2-fluoro-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	6.64	-12.77	1	4	0	51	359.22	3	↓ MOL2 SDF SMILES Flexibase

48964423

Analogs

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Popular Name: N-(4-bromo-3-methyl-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-bromo-3-methyl-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.82	7.14	-16.47	1	4	0	51	355.257	3	↓ MOL2 SDF SMILES Flexibase

48964438

Analogs

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Popular Name: N-(2-chloro-4-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2-chloro-4-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	6.61	-12.96	1	4	0	51	314.769	3	↓ MOL2 SDF SMILES Flexibase

48964467

Analogs

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Popular Name: N-(2,3-dichlorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2,3-dichlorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	7.01	-12.99	1	4	0	51	331.224	3	↓ MOL2 SDF SMILES Flexibase

48964480

Analogs

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Popular Name: N-(3,4-difluorophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(3,4-difluorophenyl)-2-(4,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.89	6.03	-20.85	1	4	0	51	298.314	3	↓ MOL2 SDF SMILES Flexibase

48964685

Analogs

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Popular Name: N-(2,4-dibromophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2,4-dibromophenyl)-2-(4,5-dim…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.18	7.29	-12.55	1	4	0	51	420.126	3	↓ MOL2 SDF SMILES Flexibase

48965036

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(2,6-dimethylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.49	7.47	-16.12	1	4	0	51	290.388	3	↓ MOL2 SDF SMILES Flexibase

48965714

Analogs

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Popular Name: 2-(4,5-dimethyl-2-oxo-thiazol-3-yl)-N-(2-ethylphenyl)acetamide 2-(4,5-dimethyl-2-oxo-thiazol-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	7.62	-16.19	1	4	0	51	290.388	4	↓ MOL2 SDF SMILES Flexibase

48965827

Analogs

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Popular Name: N-(4-bromo-2-chloro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-bromo-2-chloro-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.05	7.16	-12.65	1	4	0	51	375.675	3	↓ MOL2 SDF SMILES Flexibase

48966469

Analogs

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Popular Name: N-(3-chloro-2-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(3-chloro-2-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.38	6.51	-13.36	1	4	0	51	314.769	3	↓ MOL2 SDF SMILES Flexibase

48966745

Analogs

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Popular Name: N-(5-chloro-2-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(5-chloro-2-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	6.53	-14.82	1	4	0	51	314.769	3	↓ MOL2 SDF SMILES Flexibase

48973797

Analogs

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Popular Name: N-(2,5-dibromophenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2,5-dibromophenyl)-2-(4,5-dim…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.18	7.3	-14.24	1	4	0	51	420.126	3	↓ MOL2 SDF SMILES Flexibase

48973908

Analogs

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Popular Name: N-(2-bromo-4-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(2-bromo-4-fluoro-phenyl)-2-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	6.74	-12.8	1	4	0	51	359.22	3	↓ MOL2 SDF SMILES Flexibase

48973920

Analogs

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Popular Name: N-(4-chloro-3-fluoro-phenyl)-2-(4,5-dimethyl-2-oxo-thiazol-3-yl)acetamide N-(4-chloro-3-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	6.48	-19.7	1	4	0	51	314.769	3	↓ MOL2 SDF SMILES Flexibase

48974079

Analogs

34670422
34670446

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Popular Name: N-(3,4-difluorophenyl)-N-methyl-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(3,4-difluorophenyl)-N-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.91	6.99	-16.09	0	4	0	42	298.314	3	↓ MOL2 SDF SMILES Flexibase

49305065

Analogs

16725499

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-N-methyl-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(2,5-dimethylphenyl)-N-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.48	8.69	-17.15	0	4	0	42	290.388	3	↓ MOL2 SDF SMILES Flexibase

49305110

Analogs

37978722

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,5-dimethylphenyl)-N-methyl-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(3,5-dimethylphenyl)-N-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.48	8.22	-17.24	0	4	0	42	290.388	3	↓ MOL2 SDF SMILES Flexibase

49305134

Analogs

16725499
34670424

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-N-methyl-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(2,3-dimethylphenyl)-N-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.45	8.56	-17.26	0	4	0	42	290.388	3	↓ MOL2 SDF SMILES Flexibase

49305703

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-chloro-2-methylsulfanyl-phenyl)-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide N-(5-chloro-2-methylsulfanyl-phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.45	6.85	-15.8	1	4	0	51	328.846	4	↓ MOL2 SDF SMILES Flexibase

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SQL Query Was

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