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ZINC Item

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51482644

Analogs

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Popular Name: N-[3-(hydroxymethyl)phenyl]-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-[3-(hydroxymethyl)phenyl]-2-(6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	4.94	-20.35	2	6	0	84	335.363	5	↓ MOL2 SDF SMILES Flexibase

52892704

Analogs

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Popular Name: N-[2-chloro-6-(trifluoromethyl)phenyl]-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-[2-chloro-6-(trifluoromethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.09	9.53	-17.55	1	5	0	64	407.779	5	↓ MOL2 SDF SMILES Flexibase

20893735

Analogs

21785581
21785583
21785586
21785589
21785593

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Popular Name: 2-[3-[3-(diethylsulfamoyl)-4-methyl-phenyl]-6-oxo-pyridazin-1-yl]-N-(4-isopropylphenyl)acetamide 2-[3-[3-(diethylsulfamoyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	10.17	-25.64	1	8	0	101	496.633	9	↓ MOL2 SDF SMILES Flexibase

20893738

Analogs

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Popular Name: 2-[3-[3-(diethylsulfamoyl)-4-methyl-phenyl]-6-oxo-pyridazin-1-yl]-N-(2-fluorophenyl)acetamide 2-[3-[3-(diethylsulfamoyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.17	8.31	-24.13	1	8	0	101	472.542	8	↓ MOL2 SDF SMILES Flexibase

20893741

Analogs

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Popular Name: N-(3-cyanophenyl)-2-[3-[3-(diethylsulfamoyl)-4-methyl-phenyl]-6-oxo-pyridazin-1-yl]acetamide N-(3-cyanophenyl)-2-[3-[3-(dieth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.79	8.63	-31.04	1	9	0	125	479.562	8	↓ MOL2 SDF SMILES Flexibase

20893744

Analogs

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Popular Name: 2-[3-[3-(diethylsulfamoyl)-4-methyl-phenyl]-6-oxo-pyridazin-1-yl]-N-(2,5-difluorophenyl)acetamide 2-[3-[3-(diethylsulfamoyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.31	8.38	-25.17	1	8	0	101	490.532	8	↓ MOL2 SDF SMILES Flexibase

20894545

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-[3-(4-fluorophenyl)-6-oxo-pyridazin-1-yl]acetamide N-(5-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.83	8.96	-20.63	1	5	0	64	371.799	4	↓ MOL2 SDF SMILES Flexibase

20894548

Analogs

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Popular Name: N-(2-bromo-4-methyl-phenyl)-2-[3-(4-fluorophenyl)-6-oxo-pyridazin-1-yl]acetamide N-(2-bromo-4-methyl-phenyl)-2-[3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.96	9.07	-16.14	1	5	0	64	416.25	4	↓ MOL2 SDF SMILES Flexibase

54658752

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-(4-bromo-2-fluoro-phenyl)-2-(6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	8.34	-13.89	1	5	0	64	402.223	4	↓ MOL2 SDF SMILES Flexibase

24990452

Analogs

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Popular Name: N-(5-chloro-2-cyano-phenyl)-2-[6-oxo-3-phenyl-5-(trifluoromethyl)pyridazin-1-yl]acetamide N-(5-chloro-2-cyano-phenyl)-2-[6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.80	9.6	-16.93	1	6	0	88	432.789	5	↓ MOL2 SDF SMILES Flexibase

54845954

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	8.6	-17.14	1	7	0	90	363.373	6	↓ MOL2 SDF SMILES Flexibase

54851402

Analogs

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Popular Name: N-(2,4-dichlorophenyl)-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-(2,4-dichlorophenyl)-2-(6-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.90	8.75	-13.57	1	5	0	64	374.227	4	↓ MOL2 SDF SMILES Flexibase

54858811

Analogs

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Popular Name: N-(4-chloro-2-fluoro-phenyl)-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-(4-chloro-2-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	8.23	-13.89	1	5	0	64	357.772	4	↓ MOL2 SDF SMILES Flexibase

58324418

Analogs

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Popular Name: N-(3,4-dimethoxyphenyl)-N-methyl-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-(3,4-dimethoxyphenyl)-N-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	8.49	-21.1	0	7	0	74	379.416	6	↓ MOL2 SDF SMILES Flexibase

54915253

Analogs

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Popular Name: N-butyl-2-(6-oxo-3-phenyl-pyridazin-1-yl)-N-phenyl-acetamide N-butyl-2-(6-oxo-3-phenyl-pyrida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	11.71	-15.12	0	5	0	55	361.445	7	↓ MOL2 SDF SMILES Flexibase

65552643

Analogs

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Popular Name: N-(3-fluorophenyl)-2-[3-(2-fluorophenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-fluorophenyl)-2-[3-(2-fluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.87	7.83	-21.85	1	5	0	64	341.317	4	↓ MOL2 SDF SMILES Flexibase

55616307

Analogs

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Popular Name: N-(2-ethoxy-4-methyl-phenyl)-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-(2-ethoxy-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	8.63	-16.42	1	6	0	73	363.417	6	↓ MOL2 SDF SMILES Flexibase

55639094

Analogs

55639092

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Popular Name: N-[4-[(1S)-1-methylpropoxy]phenyl]-2-(6-oxo-3-phenyl-pyridazin-1-yl)acetamide N-[4-[(1S)-1-methylpropoxy]pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	9.31	-17.83	1	6	0	73	377.444	7	↓ MOL2 SDF SMILES Flexibase

67640796

Analogs

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Popular Name: N-(2,4-dimethoxyphenyl)-2-[3-(4-methylsulfanylphenyl)-6-oxo-pyridazin-1-yl]acetamide N-(2,4-dimethoxyphenyl)-2-[3-(4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	7.34	-17.32	1	7	0	82	411.483	7	↓ MOL2 SDF SMILES Flexibase

67640811

Analogs

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Popular Name: 2-[3-(2-chlorophenyl)-6-oxo-pyridazin-1-yl]-N-(3-methoxyphenyl)acetamide 2-[3-(2-chlorophenyl)-6-oxo-pyri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.59	-18.18	1	6	0	73	369.808	5	↓ MOL2 SDF SMILES Flexibase

49543724

Analogs

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Popular Name: 2-[3-(2-fluoro-4-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(3,4,5-trimethoxyphenyl)acetamide 2-[3-(2-fluoro-4-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.39	6.2	-23.93	1	9	0	101	443.431	8	↓ MOL2 SDF SMILES Flexibase

49543939

Analogs

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Popular Name: N-(4-bromophenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(4-bromophenyl)-2-[3-(4-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.57	7.96	-18.23	1	6	0	73	432.249	5	↓ MOL2 SDF SMILES Flexibase

49544164

Analogs

5388877
5388878

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	9.19	-19.65	1	8	0	100	421.453	8	↓ MOL2 SDF SMILES Flexibase

49545835

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(3,4,5-trimethoxyphenyl)acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.39	6.47	-22.51	1	9	0	101	443.431	8	↓ MOL2 SDF SMILES Flexibase

49546134

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(3-methoxyphenyl)acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	6.62	-19.16	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

49546580

Analogs

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Popular Name: N-(3,5-dimethoxyphenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3,5-dimethoxyphenyl)-2-[3-(4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	5.92	-21.6	1	8	0	92	413.405	7	↓ MOL2 SDF SMILES Flexibase

49546770

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(4-methoxyphenyl)acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.82	6.62	-19.58	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

49546966

Analogs

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	9.63	-20.72	1	8	0	100	439.443	8	↓ MOL2 SDF SMILES Flexibase

49547161

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-2-[3-(4-methoxyphenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-chloro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.33	6.75	-20.88	1	7	0	82	399.834	6	↓ MOL2 SDF SMILES Flexibase

49547394

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-phenyl-acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.76	7.33	-18.94	1	6	0	73	353.353	5	↓ MOL2 SDF SMILES Flexibase

49547733

Analogs

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Popular Name: 2-[3-(2-fluorophenyl)-6-oxo-pyridazin-1-yl]-N-(2-methoxyphenyl)acetamide 2-[3-(2-fluorophenyl)-6-oxo-pyri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.74	7.19	-19.62	1	6	0	73	353.353	5	↓ MOL2 SDF SMILES Flexibase

49547790

Analogs

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Popular Name: N-(2,5-dimethoxyphenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(2,5-dimethoxyphenyl)-2-[3-(4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	6.03	-21.38	1	8	0	92	413.405	7	↓ MOL2 SDF SMILES Flexibase

49547846

Analogs

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Popular Name: N-(3-bromophenyl)-2-[3-(4-methoxyphenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-bromophenyl)-2-[3-(4-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.46	7.52	-18.71	1	6	0	73	414.259	5	↓ MOL2 SDF SMILES Flexibase

49547932

Analogs

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Popular Name: N-(3-bromophenyl)-2-[3-(2-fluorophenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-bromophenyl)-2-[3-(2-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	8.38	-20.53	1	5	0	64	402.223	4	↓ MOL2 SDF SMILES Flexibase

49548264

Analogs

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Popular Name: 4-[[2-[3-(4-fluorophenyl)-6-oxo-pyridazin-1-yl]acetyl]amino]benzamide 4-[[2-[3-(4-fluorophenyl)-6-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	4.47	-24.85	3	7	0	107	366.352	5	↓ MOL2 SDF SMILES Flexibase

49548411

Analogs

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Popular Name: N-(4-tert-butylphenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(4-tert-butylphenyl)-2-[3-(4-f…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	9.65	-18.5	1	6	0	73	409.461	6	↓ MOL2 SDF SMILES Flexibase

49548507

Analogs

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Popular Name: N-(3-acetamidophenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-acetamidophenyl)-2-[3-(4-fl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.23	-24.87	2	8	0	102	410.405	6	↓ MOL2 SDF SMILES Flexibase

49548751

Analogs

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Popular Name: N-(4-chlorophenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(4-chlorophenyl)-2-[3-(4-fluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	7.85	-18.33	1	6	0	73	387.798	5	↓ MOL2 SDF SMILES Flexibase

49549093

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(3,4,5-trifluorophenyl)acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	7.52	-19.76	1	6	0	73	407.323	5	↓ MOL2 SDF SMILES Flexibase

49549298

Analogs

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Popular Name: 2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(2-methoxyphenyl)acetamide 2-[3-(4-fluoro-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.77	-18.74	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

49549503

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.93	7.99	-22.43	1	8	0	100	411.389	7	↓ MOL2 SDF SMILES Flexibase

49549669

Analogs

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Popular Name: 2-[3-(4-methoxyphenyl)-6-oxo-pyridazin-1-yl]-N-(3,4,5-trifluorophenyl)acetamide 2-[3-(4-methoxyphenyl)-6-oxo-pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	7.08	-18.73	1	6	0	73	389.333	5	↓ MOL2 SDF SMILES Flexibase

49549924

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(5-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	7.27	-18.99	1	7	0	82	417.824	6	↓ MOL2 SDF SMILES Flexibase

49550593

Analogs

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Popular Name: N-(3-bromophenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-bromophenyl)-2-[3-(4-fluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.55	7.95	-19.82	1	6	0	73	432.249	5	↓ MOL2 SDF SMILES Flexibase

49550720

Analogs

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Popular Name: N-(3-chlorophenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-chlorophenyl)-2-[3-(4-fluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	7.86	-19.94	1	6	0	73	387.798	5	↓ MOL2 SDF SMILES Flexibase

49550732

Analogs

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Popular Name: N-(3-acetylphenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(3-acetylphenyl)-2-[3-(4-fluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	7.81	-27.54	1	7	0	90	395.39	6	↓ MOL2 SDF SMILES Flexibase

49550747

Analogs

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Popular Name: N-(4-acetylphenyl)-2-[3-(4-fluoro-2-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(4-acetylphenyl)-2-[3-(4-fluor…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.66	7.81	-21.13	1	7	0	90	395.39	6	↓ MOL2 SDF SMILES Flexibase

49550751

Analogs

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Popular Name: N-(4-tert-butylphenyl)-2-[3-(2-fluoro-4-methoxy-phenyl)-6-oxo-pyridazin-1-yl]acetamide N-(4-tert-butylphenyl)-2-[3-(2-f…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	9.38	-19.32	1	6	0	73	409.461	6	↓ MOL2 SDF SMILES Flexibase

49550764

Analogs

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Popular Name: 2-[3-(2-fluoro-4-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(3-methoxyphenyl)acetamide 2-[3-(2-fluoro-4-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	6.34	-19.91	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

49550779

Analogs

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Popular Name: 2-[3-(2-fluoro-4-methoxy-phenyl)-6-oxo-pyridazin-1-yl]-N-(4-methoxyphenyl)acetamide 2-[3-(2-fluoro-4-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.82	6.35	-20.24	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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