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Analogs

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Popular Name: 1-benzyl-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-2-oxo-1,8-naphthyridine-3-carboxamide 1-benzyl-N-[4-[(2,6-dimethylpyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 10.76 -58.67 1 10 -1 138 539.597 7 ↓
Lo Low (pH 4.5-6) 2.98 11.14 -20.61 2 10 0 136 540.605 7 ↓

Analogs

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Popular Name: N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-2-oxo-1-(p-tolylmethyl)-1,8-naphthyridine-3-carb N-[4-[(2,6-dimethylpyrimidin-4-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 11.4 -58.96 1 10 -1 138 553.624 7 ↓
Lo Low (pH 4.5-6) 3.43 11.8 -20.79 2 10 0 136 554.632 7 ↓

Analogs

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Popular Name: N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-1-[(4-fluorophenyl)methyl]-2-oxo-1,8-naphthyridi N-[4-[(2,6-dimethylpyrimidin-4-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.15 10.82 -58.55 1 10 -1 138 557.587 7 ↓
Lo Low (pH 4.5-6) 3.15 11.2 -20.63 2 10 0 136 558.595 7 ↓

Analogs

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Popular Name: N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-1-[(2-fluorophenyl)methyl]-2-oxo-1,8-naphthyridi N-[4-[(2,6-dimethylpyrimidin-4-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.10 10.65 -61.78 1 10 -1 138 557.587 7 ↓
Lo Low (pH 4.5-6) 3.10 11.02 -22.99 2 10 0 136 558.595 7 ↓

Analogs

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Popular Name: 1-[(4-chlorophenyl)methyl]-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-2-oxo-1,8-naphthyridi 1-[(4-chlorophenyl)methyl]-N-[4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.66 11.27 -58.09 1 10 -1 138 574.042 7 ↓
Lo Low (pH 4.5-6) 3.66 11.65 -20.06 2 10 0 136 575.05 7 ↓

Parameters Provided:

ring.id = 199221
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 199221 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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