UCSF
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Analogs

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Popular Name: 2-oxo-1-(p-tolylmethyl)-N-[4-(thiazol-2-ylsulfamoyl)phenyl]-1,8-naphthyridine-3-carboxamide 2-oxo-1-(p-tolylmethyl)-N-[4-(th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.76 9.95 -56.68 1 9 -1 125 530.611 7 ↓
Mid Mid (pH 6-8) 4.69 10.51 -22.69 2 9 0 126 531.619 6 ↓

Analogs

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Popular Name: 1-[(4-fluorophenyl)methyl]-2-oxo-N-[4-(thiazol-2-ylsulfamoyl)phenyl]-1,8-naphthyridine-3-carboxamide 1-[(4-fluorophenyl)methyl]-2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.48 9.34 -56.52 1 9 -1 125 534.574 7 ↓
Mid Mid (pH 6-8) 4.40 9.9 -22.68 2 9 0 126 535.582 6 ↓

Analogs

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Popular Name: 1-[(2-fluorophenyl)methyl]-2-oxo-N-[4-(thiazol-2-ylsulfamoyl)phenyl]-1,8-naphthyridine-3-carboxamide 1-[(2-fluorophenyl)methyl]-2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 9.75 -55.43 1 9 -1 125 534.574 7 ↓
Mid Mid (pH 6-8) 4.36 10.31 -22.13 2 9 0 126 535.582 6 ↓

Analogs

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Popular Name: 1-[(4-chlorophenyl)methyl]-2-oxo-N-[4-(thiazol-2-ylsulfamoyl)phenyl]-1,8-naphthyridine-3-carboxamide 1-[(4-chlorophenyl)methyl]-2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.99 9.79 -56.06 1 9 -1 125 551.029 7 ↓
Mid Mid (pH 6-8) 4.92 10.35 -22.21 2 9 0 126 552.037 6 ↓

Parameters Provided:

ring.id = 199268
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 199268 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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