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Analogs

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Popular Name: 2-Bromo-5-(cyclohexyloxy)pyrazine 2-Bromo-5-(cyclohexyloxy)pyrazine

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.81 3.61 -3.1 0 3 0 35 257.131 2 ↓

Analogs

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Popular Name: 2-chloro-6-[(1S,3R)-3-methoxycyclohexoxy]pyrazine 2-chloro-6-[(1S,3R)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 2.53 -3.73 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-6-[(1S,3S)-3-methoxycyclohexoxy]pyrazine 2-chloro-6-[(1S,3S)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 2.62 -3.56 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-6-[(1R,3R)-3-methoxycyclohexoxy]pyrazine 2-chloro-6-[(1R,3R)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 2.68 -4.78 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-6-[(1R,3S)-3-methoxycyclohexoxy]pyrazine 2-chloro-6-[(1R,3S)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 2.53 -3.73 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-3-[(1S,3R)-3-methoxycyclohexoxy]pyrazine 2-chloro-3-[(1S,3R)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 2.59 -7.26 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-3-[(1S,3S)-3-methoxycyclohexoxy]pyrazine 2-chloro-3-[(1S,3S)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 2.68 -6.69 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-3-[(1R,3R)-3-methoxycyclohexoxy]pyrazine 2-chloro-3-[(1R,3R)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 2.74 -7.05 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: 2-chloro-3-[(1R,3S)-3-methoxycyclohexoxy]pyrazine 2-chloro-3-[(1R,3S)-3-methoxycyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 2.59 -7.29 0 4 0 44 242.706 3 ↓

Analogs

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Popular Name: [3-[(1S,3R)-3-methoxycyclohexoxy]pyrazin-2-yl]methanamine [3-[(1S,3R)-3-methoxycyclohexoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 0.15 -40.7 3 5 1 72 238.311 4 ↓
Mid Mid (pH 6-8) 0.97 -0.25 -6.34 2 5 0 70 237.303 4 ↓

Analogs

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Popular Name: [3-[(1S,3S)-3-methoxycyclohexoxy]pyrazin-2-yl]methanamine [3-[(1S,3S)-3-methoxycyclohexoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 0.25 -43.34 3 5 1 72 238.311 4 ↓
Mid Mid (pH 6-8) 0.97 -0.15 -5.63 2 5 0 70 237.303 4 ↓

Analogs

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Popular Name: [3-[(1R,3R)-3-methoxycyclohexoxy]pyrazin-2-yl]methanamine [3-[(1R,3R)-3-methoxycyclohexoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 0.31 -41.54 3 5 1 72 238.311 4 ↓
Mid Mid (pH 6-8) 0.97 -0.1 -6.87 2 5 0 70 237.303 4 ↓

Analogs

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Popular Name: [3-[(1R,3S)-3-methoxycyclohexoxy]pyrazin-2-yl]methanamine [3-[(1R,3S)-3-methoxycyclohexoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 0.16 -40.46 3 5 1 72 238.311 4 ↓
Mid Mid (pH 6-8) 0.97 -0.25 -6.4 2 5 0 70 237.303 4 ↓

Analogs

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Popular Name: 3-[(1S,3R)-3-methoxycyclohexoxy]pyrazine-2-carbonitrile 3-[(1S,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 2.46 -10.87 0 5 0 68 233.271 3 ↓

Analogs

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Popular Name: 3-[(1S,3S)-3-methoxycyclohexoxy]pyrazine-2-carbonitrile 3-[(1S,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 2.55 -10.17 0 5 0 68 233.271 3 ↓

Analogs

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Popular Name: 3-[(1R,3R)-3-methoxycyclohexoxy]pyrazine-2-carbonitrile 3-[(1R,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 2.61 -9.59 0 5 0 68 233.271 3 ↓

Analogs

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Popular Name: 3-[(1R,3S)-3-methoxycyclohexoxy]pyrazine-2-carbonitrile 3-[(1R,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 2.46 -10.87 0 5 0 68 233.271 3 ↓

Analogs

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Popular Name: 3-[(1S,3R)-3-methoxycyclohexoxy]pyrazine-2-carbothioamide 3-[(1S,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 1.74 -14.05 2 5 0 70 267.354 4 ↓

Analogs

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Popular Name: 3-[(1S,3S)-3-methoxycyclohexoxy]pyrazine-2-carbothioamide 3-[(1S,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 1.71 -11.61 2 5 0 70 267.354 4 ↓

Analogs

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Popular Name: 3-[(1R,3R)-3-methoxycyclohexoxy]pyrazine-2-carbothioamide 3-[(1R,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 1.89 -12.55 2 5 0 70 267.354 4 ↓

Analogs

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Popular Name: 3-[(1R,3S)-3-methoxycyclohexoxy]pyrazine-2-carbothioamide 3-[(1R,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 1.74 -14.05 2 5 0 70 267.354 4 ↓

Analogs

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Popular Name: 3-[(1S,3R)-3-methoxycyclohexoxy]pyrazine-2-carboxamidine 3-[(1S,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.17 0.33 -28.88 4 6 1 96 251.31 4 ↓

Analogs

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Popular Name: 3-[(1S,3S)-3-methoxycyclohexoxy]pyrazine-2-carboxamidine 3-[(1S,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.17 0.41 -30.17 4 6 1 96 251.31 4 ↓

Analogs

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Popular Name: 3-[(1S,3R)-3-methoxycyclohexoxy]pyrazine-2-carboxylic 3-[(1S,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.43 -58.6 0 6 -1 84 251.262 4 ↓

Analogs

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Popular Name: 3-[(1S,3S)-3-methoxycyclohexoxy]pyrazine-2-carboxylic 3-[(1S,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.46 -56.93 0 6 -1 84 251.262 4 ↓

Analogs

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Popular Name: 3-[(1R,3R)-3-methoxycyclohexoxy]pyrazine-2-carboxylic 3-[(1R,3R)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.58 -57.35 0 6 -1 84 251.262 4 ↓

Analogs

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Popular Name: 3-[(1R,3S)-3-methoxycyclohexoxy]pyrazine-2-carboxylic 3-[(1R,3S)-3-methoxycyclohexoxy]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.43 -58.6 0 6 -1 84 251.262 4 ↓

Parameters Provided:

ring.id = 20212
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 20212 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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