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Analogs

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Popular Name: 2-bromothieno[3,2-c]pyridin-4(5H)-one 2-bromothieno[3,2-c]pyridin-4(5H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 3.53 -12.59 1 2 0 33 230.086 0 ↓

Analogs

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Popular Name: 2,5-dimethyl-4-oxo-N-propyl-thieno[3,2-c]pyridine-3-carboxamide 2,5-dimethyl-4-oxo-N-propyl-thie…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 5.07 -21.49 1 4 0 51 264.35 3 ↓

Analogs

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Popular Name: N-(1,1-dimethylpropyl)-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-(1,1-dimethylpropyl)-2,5-dimet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 6.11 -20 1 4 0 51 292.404 3 ↓

Analogs

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Popular Name: 2,5-dimethyl-N-[(1R)-1-methylpropyl]-4-oxo-thieno[3,2-c]pyridine-3-carboxamide 2,5-dimethyl-N-[(1R)-1-methylpro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 6.07 -20.84 1 4 0 51 278.377 3 ↓

Analogs

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Popular Name: 2,5-dimethyl-N-[(1S)-1-methylpropyl]-4-oxo-thieno[3,2-c]pyridine-3-carboxamide 2,5-dimethyl-N-[(1S)-1-methylpro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 6.07 -21.19 1 4 0 51 278.377 3 ↓

Analogs

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Popular Name: N-tert-butyl-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-tert-butyl-2,5-dimethyl-4-oxo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 5.63 -20.53 1 4 0 51 278.377 2 ↓

Analogs

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Popular Name: N-cyclopentyl-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-cyclopentyl-2,5-dimethyl-4-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 6.49 -21.69 1 4 0 51 290.388 2 ↓

Analogs

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Popular Name: N-isobutyl-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-isobutyl-2,5-dimethyl-4-oxo-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 5.84 -21.48 1 4 0 51 278.377 3 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-(cyclopropylmethyl)-2,5-dimeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.43 5.88 -21.64 1 4 0 51 276.361 3 ↓

Analogs

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Popular Name: 2,5-dimethyl-3-(pyrrolidine-1-carbonyl)thieno[3,2-c]pyridin-4-one 2,5-dimethyl-3-(pyrrolidine-1-ca…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.74 6.72 -24.18 0 4 0 42 276.361 1 ↓

Analogs

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Popular Name: 2,5-dimethyl-3-(piperidine-1-carbonyl)thieno[3,2-c]pyridin-4-one 2,5-dimethyl-3-(piperidine-1-car…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 7.45 -22.71 0 4 0 42 290.388 1 ↓

Analogs

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Popular Name: 2,5-dimethyl-3-(morpholine-4-carbonyl)thieno[3,2-c]pyridin-4-one 2,5-dimethyl-3-(morpholine-4-car…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.18 5.02 -23.13 0 5 0 52 292.36 1 ↓

Analogs

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Popular Name: 2,5-dimethyl-4-oxo-N-phenyl-thieno[3,2-c]pyridine-3-carboxamide 2,5-dimethyl-4-oxo-N-phenyl-thie…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 7.21 -22.42 1 4 0 51 298.367 2 ↓

Analogs

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Popular Name: N,N-diethyl-2,5-dimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N,N-diethyl-2,5-dimethyl-4-oxo-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.09 7.13 -21.91 0 4 0 42 278.377 3 ↓

Analogs

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Popular Name: N-tert-butyl-5-ethyl-2-methyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-tert-butyl-5-ethyl-2-methyl-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 6.54 -20.04 1 4 0 51 292.404 3 ↓

Analogs

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Popular Name: N-cyclopropyl-5-ethyl-2-methyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide N-cyclopropyl-5-ethyl-2-methyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.30 6.12 -21.36 1 4 0 51 276.361 3 ↓

Analogs

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Popular Name: 5-ethyl-2-methyl-3-(pyrrolidine-1-carbonyl)thieno[3,2-c]pyridin-4-one 5-ethyl-2-methyl-3-(pyrrolidine-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.12 7.64 -23.92 0 4 0 42 290.388 2 ↓

Analogs

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Popular Name: N,N,2-trimethyl-4-oxo-5-propyl-thieno[3,2-c]pyridine-3-carboxamide N,N,2-trimethyl-4-oxo-5-propyl-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 7.07 -22.29 0 4 0 42 278.377 3 ↓

Analogs

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Popular Name: 5-isobutyl-N,N,2-trimethyl-4-oxo-thieno[3,2-c]pyridine-3-carboxamide 5-isobutyl-N,N,2-trimethyl-4-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.52 -22.03 0 4 0 42 292.404 3 ↓

Analogs

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Popular Name: 3-Bromothieno[3,2-c]pyridin-4(5H)-one 3-Bromothieno[3,2-c]pyridin-4(5H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 3.43 -12.99 1 2 0 33 230.086 0 ↓

Analogs

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Popular Name: 7-bromo-2-(4-pyridyl)-5H-thieno[3,2-c]pyridin-4-one 7-bromo-2-(4-pyridyl)-5H-thieno[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 5.36 -11.24 1 3 0 46 307.172 1 ↓
Lo Low (pH 4.5-6) 2.84 5.85 -39.8 2 3 1 47 308.18 0 ↓

Analogs

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Popular Name: 7-(4-hydroxyphenyl)-2-(4-pyridyl)-5H-thieno[3,2-c]pyridin-4-one 7-(4-hydroxyphenyl)-2-(4-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 5.65 -13.69 2 4 0 66 320.373 2 ↓
Lo Low (pH 4.5-6) 3.35 6.09 -42.09 3 4 1 67 321.381 1 ↓

Parameters Provided:

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