UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 1-[(1-butyltetrazol-5-yl)methyl]-3-(4-methoxyphenyl)-imidazolidine-2,4,5-trione 1-[(1-butyltetrazol-5-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.42 2.45 -12.91 0 10 0 113 358.358 7 ↓

Analogs

6605422
6605422
4789203
4789203
4789193
4789193

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Popular Name: 2-(3-butyl-2,4,5-trioxo-imidazolidin-1-yl)-N-(2,6-dichlorophenyl)-acetamide 2-(3-butyl-2,4,5-trioxo-imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.07 0.46 -13.12 1 7 0 90 372.208 6 ↓

Analogs

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Popular Name: 1-[(8-chloro-2,6-dioxabicyclo[5.4.0]undeca-7,9,11-trien-10-yl)methyl]-3-isobutyl-imidazolidine-2,4,5 1-[(8-chloro-2,6-dioxabicyclo[5.…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.87 0.45 -9.28 0 7 0 79 366.801 4 ↓

Analogs

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Popular Name: N-[2-(carbamoylmethylsulfanyl)phenyl]-2-(3-isobutyl-2,4,5-trioxo-imidazolidin-1-yl)-acetamide N-[2-(carbamoylmethylsulfanyl)ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.39 -2.87 -18.77 3 9 0 133 392.437 8 ↓

Analogs

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Popular Name: 2-(3-isobutyl-2,4,5-trioxo-imidazolidin-1-yl)-N-[4-(2-oxopyrrolidin-1-yl)phenyl]-acetamide 2-(3-isobutyl-2,4,5-trioxo-imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.14 -0.06 -23.54 1 9 0 110 386.408 6 ↓

Analogs

7151217
7151217

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Popular Name: 2-(3-benzyl-2,4,5-trioxo-imidazolidin-1-yl)-N-cyclopropyl-N-(1,1-dioxothiolan-3-yl)-acetamide 2-(3-benzyl-2,4,5-trioxo-imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.60 5.9 -21.74 0 9 0 116 419.459 6 ↓

Analogs

7151216
7151216

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Popular Name: 2-(3-benzyl-2,4,5-trioxo-imidazolidin-1-yl)-N-cyclopropyl-N-(1,1-dioxothiolan-3-yl)-acetamide 2-(3-benzyl-2,4,5-trioxo-imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.60 5.89 -22.81 0 9 0 116 419.459 6 ↓

Analogs

12736595
12736595

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Popular Name: 1-benzyl-3-[(8-chloro-2,6-dioxabicyclo[5.4.0]undeca-7,9,11-trien-10-yl)methyl]imidazolidine-2,4,5-tr 1-benzyl-3-[(8-chloro-2,6-dioxab…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 0.4 -9.39 0 7 0 79 400.818 4 ↓

Analogs

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Popular Name: 1-[2-(2-aminophenyl)ethyl]-3-methyl-imidazolidine-2,4,5-trione 1-[2-(2-aminophenyl)ethyl]-3-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 3.59 -6.29 2 6 0 87 247.254 3 ↓

Analogs

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Popular Name: 1-methyl-3-(3-oxo-3-piperazin-1-yl-propyl)imidazolidine-2,4,5-trione 1-methyl-3-(3-oxo-3-piperazin-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -2.51 1.72 -51.91 2 8 1 98 269.281 3 ↓
Mid Mid (pH 6-8) -2.51 0.43 -10.17 1 8 0 93 268.273 3 ↓

Analogs

6435744
6435744

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Popular Name: 1-isopropyl-3-[2-(2-methoxyphenoxy)ethyl]imidazolidine-2,4,5-trione 1-isopropyl-3-[2-(2-methoxypheno…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.61 5.93 -11.09 0 7 0 80 306.318 6 ↓

Analogs

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Popular Name: 1-(3,4-dipropoxyphenyl)-3-[(9-methyl-2-oxo-7-thia-1,5-diazabicyclo[4.3.0]nona-3,5,8-trien-4-yl)methy 1-(3,4-dipropoxyphenyl)-3-[(9-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 0.83 -15.18 0 10 0 114 484.534 9 ↓

Analogs

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Popular Name: 1-(3,4-dipropoxyphenyl)-3-[(10-oxo-1,7-diazabicyclo[4.4.0]deca-2,4,6,8-tetraen-8-yl)methyl]imidazoli 1-(3,4-dipropoxyphenyl)-3-[(10-o…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 1.45 -17.35 0 10 0 114 464.478 9 ↓

Analogs

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Popular Name: N-[4-(2-oxopyrrolidin-1-yl)phenyl]-2-[2,4,5-trioxo-3-[2-(2-thienyl)ethyl]imidazolidin-1-yl]acetamide N-[4-(2-oxopyrrolidin-1-yl)pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.44 8.47 -25.15 1 9 0 110 440.481 7 ↓

Analogs

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Popular Name: 1-[(1,3-dimethyl-2,6-dioxo-pyrimidin-4-yl)methyl]-3-[2-(2-thienyl)ethyl]imidazolidine-2,4,5-trione 1-[(1,3-dimethyl-2,6-dioxo-pyrim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.37 -0.09 -15.19 0 9 0 105 376.394 5 ↓

Analogs

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Popular Name: 1-benzyl-3-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxo-ethyl]imidazolidine-2,4,5-trione 1-benzyl-3-[2-[4-(2-fluorophenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 8.65 -13.57 0 8 0 85 424.432 5 ↓

Analogs

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Popular Name: 2-(3-benzyl-2,4,5-trioxo-imidazolidin-1-yl)-N-[(S)-phenyl-(2-thienyl)methyl]acetamide 2-(3-benzyl-2,4,5-trioxo-imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 10.56 -13.78 1 7 0 90 433.489 7 ↓

Analogs

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Popular Name: 2-(3-benzyl-2,4,5-trioxo-imidazolidin-1-yl)-N-[(R)-phenyl-(2-thienyl)methyl]acetamide 2-(3-benzyl-2,4,5-trioxo-imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 10.56 -13.83 1 7 0 90 433.489 7 ↓

Analogs

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Popular Name: 1-allyl-3-[(3-chlorobenzothiophen-2-yl)methyl]imidazolidine-2,4,5-trione 1-allyl-3-[(3-chlorobenzothiophe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.38 -7.74 0 5 0 61 334.784 4 ↓

Analogs

6435744
6435744

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Popular Name: 1-ethyl-3-[2-(2-methoxyphenoxy)ethyl]imidazolidine-2,4,5-trione 1-ethyl-3-[2-(2-methoxyphenoxy)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.24 5.35 -11.41 0 7 0 80 292.291 6 ↓

Analogs

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Popular Name: 1-(2-cyclohexen-1-ylethyl)-3-[(1-methyl-2-oxo-4-pyridyl)methyl]imidazolidine-2,4,5-trione 1-(2-cyclohexen-1-ylethyl)-3-[(1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 8.66 -15.51 0 7 0 83 343.383 5 ↓

Analogs

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Popular Name: 1-(1,1-dioxothian-4-yl)imidazolidine-2,4,5-trione 1-(1,1-dioxothian-4-yl)imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.70 -2.05 -16.63 1 7 0 106 246.244 1 ↓
Mid Mid (pH 6-8) -1.25 -4.8 -41.73 0 7 -1 109 245.236 1 ↓

Analogs

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Popular Name: 1-methyl-3-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]imidazolidine-2,4,5-trione 1-methyl-3-[[methyl-[[4-(trifluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 4.93 -8.71 0 6 0 64 329.278 5 ↓

Analogs

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Popular Name: 1-cyclopentyl-3-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]imidazolidine-2,4,5-trione 1-cyclopentyl-3-[[methyl-[[4-(tr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 7.9 -7.98 0 6 0 64 383.37 6 ↓

Analogs

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Popular Name: 1-benzyl-3-[(4-benzyl-1-piperidyl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(4-benzyl-1-piperidy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.76 10.53 -7.07 0 6 0 64 391.471 6 ↓

Analogs

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Popular Name: 1-benzyl-3-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(6,7-dimethoxy-3,4-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 7.68 -11.85 0 8 0 83 409.442 6 ↓

Analogs

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Popular Name: 1-benzyl-3-[[2-(4-chlorophenoxy)ethyl-methyl-amino]methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[[2-(4-chlorophenoxy)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.54 8.37 -9.04 0 7 0 74 401.85 8 ↓

Analogs

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Popular Name: 1-[[2-(4-chlorophenoxy)ethyl-methyl-amino]methyl]-3-ethyl-imidazolidine-2,4,5-trione 1-[[2-(4-chlorophenoxy)ethyl-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.33 5.23 -9.34 0 7 0 74 339.779 7 ↓

Analogs

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Popular Name: 2-(3-butyl-2,4,5-trioxo-imidazolidin-1-yl)-N-(1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)-acetamide 2-(3-butyl-2,4,5-trioxo-imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.07 -2.98 -19.47 2 11 0 140 393.4 6 ↓

Analogs

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Popular Name: 2-(3-butyl-2,4,5-trioxo-imidazolidin-1-yl)-N-(8-methyl-1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)-acetam 2-(3-butyl-2,4,5-trioxo-imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.30 -2.62 -19.25 2 11 0 140 407.427 6 ↓

Analogs

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Popular Name: 1-[[4-(2-hydroxyphenyl)piperazin-1-yl]methyl]-3-methyl-imidazolidine-2,4,5-trione 1-[[4-(2-hydroxyphenyl)piperazin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.09 0.77 -11.26 1 8 0 88 318.333 3 ↓

Analogs

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Popular Name: 2-(3-butyl-2,4,5-trioxo-imidazolidin-1-yl)-N-[5-(dimethylsulfamoyl)-2-methyl-phenyl]acetamide 2-(3-butyl-2,4,5-trioxo-imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.50 4.86 -21.91 1 10 0 128 424.479 8 ↓

Analogs

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Popular Name: N-[1-[(3-cyclopentyl-2,4,5-trioxo-imidazolidin-1-yl)methyl]-4-piperidyl]benzamide N-[1-[(3-cyclopentyl-2,4,5-triox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 6.71 -14.79 1 8 0 93 398.463 5 ↓

Analogs

13008004
13008004

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Popular Name: 1-[[cyclopropyl-[(3R)-1,1-dioxothiolan-3-yl]amino]methyl]-3-methyl-imidazolidine-2,4,5-trione 1-[[cyclopropyl-[(3R)-1,1-dioxot…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.52 0.12 -16.5 0 8 0 98 315.351 4 ↓

Analogs

13008003
13008003

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Popular Name: 1-[[cyclopropyl-[(3S)-1,1-dioxothiolan-3-yl]amino]methyl]-3-methyl-imidazolidine-2,4,5-trione 1-[[cyclopropyl-[(3S)-1,1-dioxot…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.52 -0.19 -16.89 0 8 0 98 315.351 4 ↓

Analogs

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Popular Name: 1-[(benzhydryl-methyl-amino)methyl]-3-cyclopentyl-imidazolidine-2,4,5-trione 1-[(benzhydryl-methyl-amino)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 11.08 -5.96 0 6 0 64 391.471 6 ↓

Analogs

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Popular Name: 1-isobutyl-3-[[3-(4-isopropylphenyl)-1,2,4-oxadiazol-5-yl]methyl]imidazolidine-2,4,5-trione 1-isobutyl-3-[[3-(4-isopropylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 7.81 -10.23 0 8 0 100 370.409 6 ↓

Analogs

53160332
53160332
5365496
5365496
6150217
6150217

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Popular Name: 1-benzyl-3-[(3-chlorophenyl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(3-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 9.38 -6.62 0 5 0 61 328.755 4 ↓

Analogs

37050672
37050672

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Popular Name: 1-benzyl-3-[2-(2-methylphenoxy)ethyl]imidazolidine-2,4,5-trione 1-benzyl-3-[2-(2-methylphenoxy)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 9.25 -9.44 0 6 0 70 338.363 6 ↓

Analogs

25254218
25254218

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Popular Name: 1-benzyl-3-[2-(4-chlorophenoxy)ethyl]imidazolidine-2,4,5-trione 1-benzyl-3-[2-(4-chlorophenoxy)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 9.05 -9.19 0 6 0 70 358.781 6 ↓

Analogs

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Popular Name: 1-benzyl-3-[(2-chloro-4-fluoro-phenyl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(2-chloro-4-fluoro-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 9.26 -6.76 0 5 0 61 346.745 4 ↓

Analogs

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Popular Name: 1-benzyl-3-[(2-methoxyphenyl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(2-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 9.44 -7.39 0 6 0 70 324.336 5 ↓

Analogs

8335263
8335263

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Popular Name: 1-benzyl-3-[(2-chloro-3-quinolyl)methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[(2-chloro-3-quinolyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 9.54 -11.19 0 6 0 74 379.803 4 ↓

Analogs

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Popular Name: 1-benzyl-3-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]imidazolidine-2,4,5-trione 1-benzyl-3-[[3-(4-methoxyphenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.93 6.89 -11.76 0 9 0 109 392.371 6 ↓

Analogs

25254732
25254732

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Popular Name: 1-ethyl-3-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]imidazolidine-2,4,5-trione 1-ethyl-3-[[3-(4-methoxyphenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.71 3.88 -11.62 0 9 0 109 330.3 5 ↓

Analogs

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Popular Name: 1-[[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]-3-cyclopentyl-imidazolidine-2,4,5-trione 1-[[3-(4-chlorophenyl)-1,2,4-oxa…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 6.91 -9.4 0 8 0 100 374.784 4 ↓

Analogs

25254732
25254732
25254743
25254743

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Popular Name: 1-isopropyl-3-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]imidazolidine-2,4,5-trione 1-isopropyl-3-[[3-(4-methoxyphen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.07 4.28 -11.78 0 9 0 109 344.327 5 ↓

Analogs

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Popular Name: 1-[2-oxo-2-(2-phenyl-1H-indol-3-yl)ethyl]-3-(2-thienylmethyl)imidazolidine-2,4,5-trione 1-[2-oxo-2-(2-phenyl-1H-indol-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 11.5 -12.92 1 7 0 94 443.484 6 ↓

Analogs

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Popular Name: 1-[2-[2,5-dimethyl-1-(5-methylisoxazol-3-yl)pyrrol-3-yl]-2-oxo-ethyl]-3-(2-thienylmethyl)imidazolidi 1-[2-[2,5-dimethyl-1-(5-methylis…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 11.1 -16.74 0 9 0 109 426.454 6 ↓

Analogs

9258006
9258006

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Popular Name: 1-(4-methoxyphenyl)-3-[2-[(2R)-2-methyl-3,4-dihydro-2H-1,5-benzothiazepin-5-yl]-2-oxo-ethyl]imidazol 1-(4-methoxyphenyl)-3-[2-[(2R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 10.36 -11.78 0 8 0 91 439.493 4 ↓

Parameters Provided:

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