UCSF
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Analogs

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Popular Name: 6-chloro-N-[(1S)-1-cyclohexylethyl]pyridazine-3-carboxamide 6-chloro-N-[(1S)-1-cyclohexyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 5.08 -5.58 1 4 0 55 267.76 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-cyclohexylethyl]pyridazine-3-carboxamide 6-chloro-N-[(1R)-1-cyclohexyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 5.05 -5.66 1 4 0 55 267.76 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-1-cyclohexylpropyl]pyridazine-3-carboxamide 6-chloro-N-[(1S)-1-cyclohexylpro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.62 5.95 -5.29 1 4 0 55 281.787 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-cyclohexylpropyl]pyridazine-3-carboxamide 6-chloro-N-[(1R)-1-cyclohexylpro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.62 6.07 -5.21 1 4 0 55 281.787 4 ↓

Analogs

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Popular Name: 6-amino-N-[(1S)-1-cyclohexylethyl]pyridazine-3-carboxamide 6-amino-N-[(1S)-1-cyclohexylethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 3.43 -8.14 3 5 0 81 248.33 3 ↓

Analogs

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Popular Name: 6-amino-N-[(1R)-1-cyclohexylethyl]pyridazine-3-carboxamide 6-amino-N-[(1R)-1-cyclohexylethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 3.71 -8.22 3 5 0 81 248.33 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylethyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclohexylethyl]-6-(me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.27 4.34 -7.86 2 5 0 67 262.357 4 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylethyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclohexylethyl]-6-(me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.27 4.62 -7.87 2 5 0 67 262.357 4 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylethyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclohexylethyl]-6-(et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 5.15 -7.28 2 5 0 67 276.384 5 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylethyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclohexylethyl]-6-(et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 5.14 -7.29 2 5 0 67 276.384 5 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylethyl]-6-(propylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclohexylethyl]-6-(pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.15 5.9 -6.96 2 5 0 67 290.411 6 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylethyl]-6-(propylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclohexylethyl]-6-(pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.15 5.89 -6.94 2 5 0 67 290.411 6 ↓

Analogs

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Popular Name: 6-amino-N-[(1S)-1-cyclohexylpropyl]pyridazine-3-carboxamide 6-amino-N-[(1S)-1-cyclohexylprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 4.3 -7.67 3 5 0 81 262.357 4 ↓

Analogs

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Popular Name: 6-amino-N-[(1R)-1-cyclohexylpropyl]pyridazine-3-carboxamide 6-amino-N-[(1R)-1-cyclohexylprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 4.43 -7.58 3 5 0 81 262.357 4 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylpropyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclohexylpropyl]-6-(m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 5.21 -7.39 2 5 0 67 276.384 5 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylpropyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclohexylpropyl]-6-(m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 5.34 -7.31 2 5 0 67 276.384 5 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylpropyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclohexylpropyl]-6-(e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 6.04 -6.82 2 5 0 67 290.411 6 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylpropyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclohexylpropyl]-6-(e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 6.16 -6.75 2 5 0 67 290.411 6 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylethyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1S)-1-cyclohexylethyl]-6-hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 3.28 -9.17 4 6 0 93 263.345 4 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylethyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1R)-1-cyclohexylethyl]-6-hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 3.57 -9.21 4 6 0 93 263.345 4 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclohexylpropyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1S)-1-cyclohexylpropyl]-6-hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 4.16 -8.69 4 6 0 93 277.372 5 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclohexylpropyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1R)-1-cyclohexylpropyl]-6-hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 4.29 -8.59 4 6 0 93 277.372 5 ↓

Analogs

546083
546083

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Popular Name: N-(cyclohexylmethyl)-6-oxo-N-propyl-1H-pyridazine-3-carboxamide N-(cyclohexylmethyl)-6-oxo-N-pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.99 4.74 -41.61 0 5 -1 69 276.36 5 ↓
Lo Low (pH 4.5-6) 2.53 6.57 -7.52 1 5 0 66 277.368 5 ↓

Analogs

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Popular Name: N-[(4-ethylcyclohexyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(4-ethylcyclohexyl)methyl]-6-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 1.71 -39.55 1 5 -1 78 262.333 4 ↓
Lo Low (pH 4.5-6) 1.86 3.55 -7.47 2 5 0 75 263.341 4 ↓

Parameters Provided:

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