UCSF
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Popular Name: 1-(4-chlorophenyl)sulfonyl-3-[4-(1H-tetrazol-5-yl)-2-(trifluoromethoxy)phenyl]urea 1-(4-chlorophenyl)sulfonyl-3-[4-…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PYGL-1-E Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic Eukaryotes 10000 0.23 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PYGL_HUMAN P06737 Liver Glycogen Phosphorylase, Human 10000 0.23 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.99 0.66 -90.52 1 10 -2 144 460.781 7 ↓
Lo Low (pH 4.5-6) 2.99 0.75 -42.88 2 10 -1 145 461.789 7 ↓
Lo Low (pH 4.5-6) 2.99 0.65 -44.98 2 10 -1 145 461.789 7 ↓

Parameters Provided:

ring.id = 222198
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 222198 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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