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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

7605531
7605531
7605565
7605565
4846539
4846539
5610394
5610394

Draw Identity 99% 90% 80% 70%

Popular Name: (1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)carbamoylmethyl (1,3-dioxo-2,4-diazaspiro[4.5]de…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.85 7.55 -16.68 2 8 0 105 373.409 5 ↓
Hi High (pH 8-9.5) 3.04 5.14 -57.5 1 8 -1 111 372.401 5 ↓

Analogs

5780724
5780724

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Popular Name: (1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)carbamoylmethyl (1,3-dioxo-2,4-diazaspiro[4.5]de…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.51 7.54 -16.29 2 8 0 105 373.409 5 ↓
Hi High (pH 8-9.5) 2.70 5.14 -57.28 1 8 -1 111 372.401 5 ↓

Analogs

5780713
5780713

Draw Identity 99% 90% 80% 70%

Popular Name: (8-methyl-1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)carbamoylmethyl (8-methyl-1,3-dioxo-2,4-diazaspi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 -1.05 -16.23 2 8 0 104 387.436 5 ↓

Analogs

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Popular Name: [2-[(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)amino]-2-oxo-ethyl] [2-[(1,3-dioxo-2,4-diazaspiro[4.…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 7.46 -21.29 2 13 0 169 464.431 9 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-[(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)amino]-2-oxo-ethyl] [2-[(8-methyl-2,4-dioxo-1,3-diaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 7.9 -21.02 2 11 0 151 483.275 6 ↓
Hi High (pH 8-9.5) 2.68 7.12 -50.97 1 11 -1 157 482.267 6 ↓

Parameters Provided:

ring.id = 2277
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 2277 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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