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ZINC Item

Suppliers, Protomers, & Similar Substances

2787696

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-chloro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(5-chloro-2-methyl-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.76	0.05	-15.23	1	5	0	59	286.722	2	↓ MOL2 SDF SMILES Flexibase

2787698

Analogs

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Popular Name: N-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dimethoxyphenyl)pyrazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	-0.01	-16.53	1	7	0	77	298.302	4	↓ MOL2 SDF SMILES Flexibase

2787756

Analogs

2788205

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-dimethylphenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	0.52	-14.65	1	5	0	59	266.304	2	↓ MOL2 SDF SMILES Flexibase

2787769

Analogs

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Popular Name: N-o-phenetylpyrazolo[1,5-a]pyrimidine-2-carboxamide N-o-phenetylpyrazolo[1,5-a]pyrim…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.09	-0.2	-15.05	1	6	0	68	282.303	4	↓ MOL2 SDF SMILES Flexibase

2787776

Analogs

2788205

Draw Identity 99% 90% 80% 70%

Popular Name: N-p-cumenylpyrazolo[1,5-a]pyrimidine-2-carboxamide N-p-cumenylpyrazolo[1,5-a]pyrimi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.21	0.44	-14.28	1	5	0	59	280.331	3	↓ MOL2 SDF SMILES Flexibase

2787824

Analogs

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Popular Name: N-(4-sulfamoylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-sulfamoylphenyl)pyrazolo[1,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.40	-6.6	-20.29	3	8	0	119	317.33	3	↓ MOL2 SDF SMILES Flexibase

2787837

Analogs

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Popular Name: N-(4-ethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-ethylphenyl)pyrazolo[1,5-a]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.62	0.12	-14.38	1	5	0	59	266.304	3	↓ MOL2 SDF SMILES Flexibase

2787893

Analogs

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Popular Name: N-[4-(methylsulfamoyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-(methylsulfamoyl)phenyl]pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.77	-5.94	-19.34	2	8	0	105	331.357	4	↓ MOL2 SDF SMILES Flexibase

2787899

Analogs

2788205

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,3-dimethylphenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	0.42	-14.69	1	5	0	59	266.304	2	↓ MOL2 SDF SMILES Flexibase

2787911

Analogs

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Popular Name: N-(2,4-difluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-difluorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	5.47	-11.94	1	5	0	59	274.23	2	↓ MOL2 SDF SMILES Flexibase

2787950

Analogs

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Popular Name: N-(2-bromophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2-bromophenyl)pyrazolo[1,5-a]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	-0.88	-13.39	1	5	0	59	317.146	2	↓ MOL2 SDF SMILES Flexibase

2788041

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-(trifluoromethyl)phenyl]pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	1.82	-13.75	1	5	0	59	306.247	3	↓ MOL2 SDF SMILES Flexibase

2788070

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-chloro-2-methyl-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	0.04	-12.91	1	5	0	59	286.722	2	↓ MOL2 SDF SMILES Flexibase

2788078

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-methoxy-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-methoxy-2-methyl-phenyl)pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.14	0.21	-15.03	1	6	0	68	282.303	3	↓ MOL2 SDF SMILES Flexibase

2788139

Analogs

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Popular Name: N-(5-fluoro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(5-fluoro-2-methyl-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.24	0.94	-16.11	1	5	0	59	270.267	2	↓ MOL2 SDF SMILES Flexibase

2788147

Analogs

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Popular Name: N-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dimethylphenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	0.19	-14.74	1	5	0	59	266.304	2	↓ MOL2 SDF SMILES Flexibase

2788150

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-difluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,5-difluorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	1.17	-14	1	5	0	59	274.23	2	↓ MOL2 SDF SMILES Flexibase

2788158

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4,5-trimethoxyphenyl)pyrazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.33	0.43	-17.66	1	8	0	86	328.328	5	↓ MOL2 SDF SMILES Flexibase

2788205

Analogs

2787756
2787776

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-tert-butylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2-tert-butylphenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	1.5	-13.85	1	5	0	59	294.358	3	↓ MOL2 SDF SMILES Flexibase

2788217

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-difluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-difluorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	1.13	-16.33	1	5	0	59	274.23	2	↓ MOL2 SDF SMILES Flexibase

2788219

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-methoxy-5-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2-methoxy-5-methyl-phenyl)pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.14	0.1	-15.6	1	6	0	68	282.303	3	↓ MOL2 SDF SMILES Flexibase

2788230

Analogs

2788359

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dichlorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.99	-0.62	-14.76	1	5	0	59	307.14	2	↓ MOL2 SDF SMILES Flexibase

2788253

Analogs

2788313

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(diethylamino)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-(diethylamino)phenyl]pyrazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	0.16	-14.98	1	6	0	62	309.373	5	↓ MOL2 SDF SMILES Flexibase

2788267

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[3-(trifluoromethyl)phenyl]pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	1.82	-16.51	1	5	0	59	306.247	3	↓ MOL2 SDF SMILES Flexibase

2788278

Analogs

2788359

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,5-dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,5-dichlorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.99	-0.64	-12.67	1	5	0	59	307.14	2	↓ MOL2 SDF SMILES Flexibase

2788279

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,5-dimethoxyphenyl)pyrazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.74	-0.21	-17.73	1	7	0	77	298.302	4	↓ MOL2 SDF SMILES Flexibase

2788301

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(pyrazolo[1,5-a]pyrimidine-2-carbonylamino)benzoic-acid-methyl-ester 2-(pyrazolo[1,5-a]pyrimidine-2-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.01	1.16	-16.99	1	7	0	85	296.286	4	↓ MOL2 SDF SMILES Flexibase

2788313

Analogs

2788253

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-dimethylaminophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-dimethylaminophenyl)pyrazol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.80	-0.29	-15.42	1	6	0	62	281.319	3	↓ MOL2 SDF SMILES Flexibase

2788341

Analogs

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Popular Name: N-[4-chloro-3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-chloro-3-(trifluoromethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.20	1.59	-12.51	1	5	0	59	340.692	3	↓ MOL2 SDF SMILES Flexibase

2788344

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-dichlorophenyl)pyrazolo[1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.99	-0.47	-11.51	1	5	0	59	307.14	2	↓ MOL2 SDF SMILES Flexibase

2788356

Analogs

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Popular Name: N-(4-acetylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-acetylphenyl)pyrazolo[1,5-a…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	0.12	-19.37	1	6	0	76	280.287	3	↓ MOL2 SDF SMILES Flexibase

2788359

Analogs

2788278
2788230

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-4-fluoro-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-chloro-4-fluoro-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.47	0.23	-15.39	1	5	0	59	290.685	2	↓ MOL2 SDF SMILES Flexibase

2788362

Analogs

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Popular Name: N-(3-ethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-ethylphenyl)pyrazolo[1,5-a]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.59	0.13	-14.09	1	5	0	59	266.304	3	↓ MOL2 SDF SMILES Flexibase

2788387

Analogs

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Popular Name: N-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[2-(trifluoromethyl)phenyl]pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.55	2.09	-13.87	1	5	0	59	306.247	3	↓ MOL2 SDF SMILES Flexibase

2788420

Analogs

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Popular Name: N-(4-fluoro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-fluoro-2-methyl-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.24	0.93	-13.72	1	5	0	59	270.267	2	↓ MOL2 SDF SMILES Flexibase

2788460

Analogs

2788461

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Popular Name: N-[4-[(1R)-1-methylpropyl]phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-[(1R)-1-methylpropyl]phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	0.6	-14.16	1	5	0	59	294.358	4	↓ MOL2 SDF SMILES Flexibase

2788461

Analogs

2788460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-[(1S)-1-methylpropyl]phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide N-[4-[(1S)-1-methylpropyl]phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	0.6	-14.16	1	5	0	59	294.358	4	↓ MOL2 SDF SMILES Flexibase

2788489

Analogs

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Popular Name: N-(3-fluoro-4-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-fluoro-4-methyl-phenyl)pyra…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.24	0.68	-16.41	1	5	0	59	270.267	2	↓ MOL2 SDF SMILES Flexibase

2790093

Analogs

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Popular Name: 3-chloro-N-(2,3,5,6-tetrafluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 3-chloro-N-(2,3,5,6-tetrafluorop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.75	2.56	-16.4	1	5	0	59	344.655	2	↓ MOL2 SDF SMILES Flexibase

2790684

Analogs

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Popular Name: 3-chloro-N-(2,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 3-chloro-N-(2,4-dichlorophenyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.59	-0.62	-12.93	1	5	0	59	341.585	2	↓ MOL2 SDF SMILES Flexibase

2790801

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-chloro-N-(2,4-difluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 3-chloro-N-(2,4-difluorophenyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	1.03	-13.47	1	5	0	59	308.675	2	↓ MOL2 SDF SMILES Flexibase

2790864

Analogs

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Popular Name: 6-bromo-N-(2,3,5,6-tetrafluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 6-bromo-N-(2,3,5,6-tetrafluoroph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.10	1.91	-9.49	1	5	0	59	389.106	2	↓ MOL2 SDF SMILES Flexibase

2791054

Analogs

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Popular Name: 6-bromo-N-(4-bromo-2-fluoro-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 6-bromo-N-(4-bromo-2-fluoro-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	6.63	-6.79	1	5	0	59	414.032	2	↓ MOL2 SDF SMILES Flexibase

2791861

Analogs

2789793

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Popular Name: N-(4-acetamidophenyl)-3-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-acetamidophenyl)-3-chloro-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.53	-1.59	-25.02	2	7	0	88	329.747	3	↓ MOL2 SDF SMILES Flexibase

2791966

Analogs

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Popular Name: 4-[(3-chloropyrazolo[1,5-a]pyrimidine-2-carbonyl)amino]benzoate 4-[(3-chloropyrazolo[1,5-a]pyrim…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.22	-0.92	-63.52	1	7	-1	99	315.696	3	↓ MOL2 SDF SMILES Flexibase

2791996

Analogs

4809996

Draw Identity 99% 90% 80% 70%

Popular Name: 6-bromo-N-(2-chloro-5-nitro-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 6-bromo-N-(2-chloro-5-nitro-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.22	-0.61	-11.77	1	8	0	105	396.588	3	↓ MOL2 SDF SMILES Flexibase

2792297

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-acetamidophenyl)-6-bromo-pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-acetamidophenyl)-6-bromo-py…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	-2.24	-17.04	2	7	0	88	374.198	3	↓ MOL2 SDF SMILES Flexibase

2792452

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(6-bromopyrazolo[1,5-a]pyrimidine-2-carbonyl)amino]benzoate 4-[(6-bromopyrazolo[1,5-a]pyrimi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	-1.57	-55.62	1	7	-1	99	360.147	3	↓ MOL2 SDF SMILES Flexibase

2792550

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(3-chloropyrazolo[1,5-a]pyrimidine-2-carbonyl)amino]benzoate 3-[(3-chloropyrazolo[1,5-a]pyrim…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.19	-0.91	-73.02	1	7	-1	99	315.696	3	↓ MOL2 SDF SMILES Flexibase

2792581

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-chloro-N-[3-chloro-4-(difluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide 3-chloro-N-[3-chloro-4-(difluoro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	0.41	-18.33	1	6	0	68	373.146	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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