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ZINC Item

Suppliers, Protomers, & Similar Substances

2788299

Analogs

2793685
2794828
2795436
2795540
2795563

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethoxyphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,5-dimethoxyphenyl)-7-(1,5-d…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.02	0.12	-21.66	1	9	0	95	392.419	5	↓ MOL2 SDF SMILES Flexibase

2794007

Analogs

2795314
2798961

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-difluorophenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,5-difluorophenyl)-7-(1,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	1.55	-17.41	1	7	0	77	368.347	3	↓ MOL2 SDF SMILES Flexibase

2794190

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-difluorophenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-difluorophenyl)-7-(1,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	1.54	-15.55	1	7	0	77	368.347	3	↓ MOL2 SDF SMILES Flexibase

2794530

Analogs

2795314
2798961

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(2-fluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.09	0.8	-17.86	1	7	0	77	350.357	3	↓ MOL2 SDF SMILES Flexibase

2794567

Analogs

2795314
2798961
6527561

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(3-fluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.11	0.76	-16.58	1	7	0	77	350.357	3	↓ MOL2 SDF SMILES Flexibase

2794640

Analogs

2798615
6527561

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-chlorophenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-chlorophenyl)-7-(1,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.65	-0.14	-16.72	1	7	0	77	366.812	3	↓ MOL2 SDF SMILES Flexibase

2794661

Analogs

2795314
2799906
6922144

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(4-fluoro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	1.26	-17.07	1	7	0	77	364.384	3	↓ MOL2 SDF SMILES Flexibase

2794715

Analogs

2798615
17094616

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-chlorophenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2-chlorophenyl)-7-(1,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	0.04	-17.26	1	7	0	77	366.812	3	↓ MOL2 SDF SMILES Flexibase

2794731

Analogs

2795314
2799906
6527561

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-acetylphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-acetylphenyl)-7-(1,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.87	0.38	-22.61	1	8	0	94	374.404	4	↓ MOL2 SDF SMILES Flexibase

2794792

Analogs

2798615
6527561

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chlorophenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-chlorophenyl)-7-(1,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.63	-0.12	-16.27	1	7	0	77	366.812	3	↓ MOL2 SDF SMILES Flexibase

2794828

Analogs

2788299

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dimethoxyphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dimethoxyphenyl)-7-(1,5-d…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.62	0.36	-19.82	1	9	0	95	392.419	5	↓ MOL2 SDF SMILES Flexibase

2795276

Analogs

2795314
2799906

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(5-fluoro-2-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	1.34	-18.94	1	7	0	77	364.384	3	↓ MOL2 SDF SMILES Flexibase

2795314

Analogs

2795318
2795374
2795486
2795540
2795577

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(2-fluoro-5-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	1.12	-17.81	1	7	0	77	364.384	3	↓ MOL2 SDF SMILES Flexibase

2795318

Analogs

2799906
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-acetylphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-acetylphenyl)-7-(1,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	0.49	-26.24	1	8	0	94	374.404	4	↓ MOL2 SDF SMILES Flexibase

2795330

Analogs

2799906

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-o-cumenyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-o…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.96	1.12	-17.6	1	7	0	77	374.448	4	↓ MOL2 SDF SMILES Flexibase

2795370

Analogs

2799906
6527561
6922144

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-dimethylphenyl)-7-(1,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	0.85	-18.24	1	7	0	77	360.421	3	↓ MOL2 SDF SMILES Flexibase

2795374

Analogs

2799906
6527561
6922144
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dimethylphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dimethylphenyl)-7-(1,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	0.56	-18.19	1	7	0	77	360.421	3	↓ MOL2 SDF SMILES Flexibase

2795436

Analogs

2788299

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(2-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	0.12	-19.42	1	8	0	86	362.393	4	↓ MOL2 SDF SMILES Flexibase

2795479

Analogs

2799906
6922144

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(2-ethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.84	0.75	-17.94	1	7	0	77	360.421	4	↓ MOL2 SDF SMILES Flexibase

2795486

Analogs

2799906
6922144
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,3-dimethylphenyl)-7-(1,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	0.75	-18.37	1	7	0	77	360.421	3	↓ MOL2 SDF SMILES Flexibase

2795494

Analogs

2798615

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-4-methoxy-phenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-chloro-4-methoxy-phenyl)-7-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	-0.07	-19.97	1	8	0	86	396.838	4	↓ MOL2 SDF SMILES Flexibase

2795514

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-chloro-2-methyl-phenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(5-chloro-2-methyl-phenyl)-7-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.03	0.46	-18.06	1	7	0	77	380.839	3	↓ MOL2 SDF SMILES Flexibase

2795539

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-2-methyl-phenyl)-7-(1,5-dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3-chloro-2-methyl-phenyl)-7-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	0.42	-16.15	1	7	0	77	380.839	3	↓ MOL2 SDF SMILES Flexibase

2795540

Analogs

2798615
2799906
6554325
6921775
19716769

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-p-phenetyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.41	0.04	-18.54	1	8	0	86	376.42	5	↓ MOL2 SDF SMILES Flexibase

2795563

Analogs

2788299

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-o-phenetyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-o…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.36	0.13	-19.3	1	8	0	86	376.42	5	↓ MOL2 SDF SMILES Flexibase

2795565

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.01	0.03	-20.8	1	8	0	86	362.393	4	↓ MOL2 SDF SMILES Flexibase

2795577

Analogs

2799906
6527561
6922144
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(o-tolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.38	0.58	-17.8	1	7	0	77	346.394	3	↓ MOL2 SDF SMILES Flexibase

2795641

Analogs

2799906
6527561
6922144
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1,5-dimethylpyrazol-4-yl)-N-(m-tolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1,5-dimethylpyrazol-4-yl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	0.35	-17.77	1	7	0	77	346.394	3	↓ MOL2 SDF SMILES Flexibase

2797743

Analogs

2798615
2799906
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dimethylphenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dimethylphenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.17	0.64	-17.92	1	7	0	77	374.448	4	↓ MOL2 SDF SMILES Flexibase

2797916

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(5-chloro-2-methyl-phenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamid N-(5-chloro-2-methyl-phenyl)-7-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	0.54	-17.75	1	7	0	77	394.866	4	↓ MOL2 SDF SMILES Flexibase

2797969

Analogs

2788299

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.38	0.11	-20.54	1	8	0	86	376.42	5	↓ MOL2 SDF SMILES Flexibase

2798063

Analogs

2798961

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-(2,3,5,6-tetrafluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxami 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.79	3.03	-17.92	1	7	0	77	418.354	4	↓ MOL2 SDF SMILES Flexibase

2798088

Analogs

2799906

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxami 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.20	2.53	-17.86	1	7	0	77	414.391	5	↓ MOL2 SDF SMILES Flexibase

2798094

Analogs

17094616

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-chloro-5-nitro-phenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2-chloro-5-nitro-phenyl)-7-(1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	0.6	-19.99	1	10	0	122	425.836	5	↓ MOL2 SDF SMILES Flexibase

2798102

Analogs

2798615
2799906
17094616

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Popular Name: N-(2,4-dichlorophenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-dichlorophenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.63	-0.02	-14.82	1	7	0	77	415.284	4	↓ MOL2 SDF SMILES Flexibase

2798128

Analogs

2798615
2799906

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-2-methyl-phenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamid N-(3-chloro-2-methyl-phenyl)-7-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	0.51	-15.84	1	7	0	77	394.866	4	↓ MOL2 SDF SMILES Flexibase

2798251

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-(2-methoxy-5-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxami 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.78	0.57	-19	1	8	0	86	390.447	5	↓ MOL2 SDF SMILES Flexibase

2798273

Analogs

2798961

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-bromo-2-fluoro-phenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(4-bromo-2-fluoro-phenyl)-7-(1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.25	8.67	-15.22	1	7	0	77	443.28	4	↓ MOL2 SDF SMILES Flexibase

2798360

Analogs

2798961
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-difluorophenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,4-difluorophenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	1.63	-15.36	1	7	0	77	382.374	4	↓ MOL2 SDF SMILES Flexibase

2798406

Analogs

2798961
2799906
2795314

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-(2-fluoro-5-methyl-phenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamid 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	1.22	-17.69	1	7	0	77	378.411	4	↓ MOL2 SDF SMILES Flexibase

2798615

Analogs

2799801
2793685
2794640
2794715

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dichlorophenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(3,4-dichlorophenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.63	-0.18	-17.25	1	7	0	77	415.284	4	↓ MOL2 SDF SMILES Flexibase

2798961

Analogs

2794007
2794530

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-difluorophenyl)-7-(1-ethyl-3-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,5-difluorophenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	1.72	-14.7	1	7	0	77	382.374	4	↓ MOL2 SDF SMILES Flexibase

2799801

Analogs

2799906
2798615

Draw Identity 99% 90% 80% 70%

Popular Name: 7-(1-ethyl-5-methyl-pyrazol-4-yl)-N-p-cumenyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide 7-(1-ethyl-5-methyl-pyrazol-4-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.86	0.9	-17.29	1	7	0	77	388.475	5	↓ MOL2 SDF SMILES Flexibase

2799906

Analogs

2793685
2794661

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-7-(1-ethyl-5-methyl-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide N-(2,3-dimethylphenyl)-7-(1-ethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.15	0.84	-18.07	1	7	0	77	374.448	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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SQL Query Was

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