UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(3-fluorophenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.97 6.04 -12.89 2 6 0 79 333.363 3 ↓

Analogs

5342188
5342188
5342190
5342190
3345113
3345113
3345115
3345115

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Popular Name: N-(4-chloro-2-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 -1.26 -13.22 2 6 0 78 363.845 3 ↓

Analogs

5342195
5342195
5342197
5342197
3435235
3435235

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(3-fluoro-4-methyl-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.37 -0.63 -16.72 2 6 0 78 347.39 3 ↓

Analogs

2622066
2622066

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Popular Name: N-(2-tert-butylphenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-tert-butylphenyl)-2-(1,3-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.49 9.06 -12.99 2 6 0 79 371.481 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2-methyl-3-nitro-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.14 -0.7 -14.19 2 9 0 124 374.397 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2-ethyl-6-methyl-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 -0.59 -12.61 2 6 0 78 357.454 4 ↓

Analogs

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Popular Name: N-(4-bromophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-bromophenyl)-2-(1,3-diketo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.64 -2.42 -13.49 2 6 0 78 394.269 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-isopropyl-N-phenyl-acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 0.52 -13.9 1 6 0 69 357.454 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-[3-(trifluoromethyl)phenyl]acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 6.98 -12.67 2 6 0 79 383.37 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-methyl-N-phenyl-acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 7.55 -16 1 6 0 70 329.4 3 ↓

Analogs

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Popular Name: N-(3-acetylphenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(3-acetylphenyl)-2-(1,3-diketo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 -1.18 -23.02 2 7 0 95 357.41 4 ↓

Analogs

16646481
16646481

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(3-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.86 -1.26 -12.51 2 6 0 78 363.845 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(3,4-dimethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 -1.05 -14.15 2 6 0 78 343.427 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(m-tolyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.25 -1.34 -14.03 2 6 0 78 329.4 3 ↓

Analogs

8658658
8658658
20796047
20796047
20796052
20796052

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2-methoxy-5-methyl-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.26 -1.2 -14.03 2 7 0 87 359.426 4 ↓

Analogs

8273683
8273683

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2,6-dimethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 -0.46 -13.77 2 6 0 78 343.427 3 ↓

Analogs

7287718
7287718
3370928
3370928
3370931
3370931

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(5-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 7.4 -15.17 2 6 0 79 363.845 3 ↓

Analogs

7005679
7005679

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Popular Name: N-(2-chlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-chlorophenyl)-2-(1,3-diketo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 -1.63 -11.98 2 6 0 78 349.818 3 ↓

Analogs

8273683
8273683

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(o-tolyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 -1.11 -13.95 2 6 0 78 329.4 3 ↓

Analogs

4469407
4469407
3463140
3463140

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(p-tolyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 6.65 -14.08 2 6 0 79 329.4 3 ↓

Analogs

3428378
3428378
3428381
3428381

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(3-chloro-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 7.08 -12.61 2 6 0 79 363.845 3 ↓

Analogs

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Popular Name: N-(2,5-dichlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,5-dichlorophenyl)-2-(1,3-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 -1.77 -12.15 2 6 0 78 384.263 3 ↓

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-bromo-2-fluoro-phenyl)-2-(1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.73 -1.64 -10.64 2 6 0 78 412.259 3 ↓

Analogs

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Popular Name: N-(2-chloro-4-fluoro-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-chloro-4-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.60 6.52 -13.07 2 6 0 79 367.808 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-o-phenetyl-acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 -1.5 -13.42 2 7 0 87 359.426 5 ↓

Analogs

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Popular Name: N-(3-cyanophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(3-cyanophenyl)-2-(1,3-diketo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 6.37 -18.38 2 7 0 102 340.383 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(4-iodophenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.91 7.08 -13.17 2 6 0 79 441.269 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(3,5-dimethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 -1.01 -14.24 2 6 0 78 343.427 3 ↓

Analogs

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Popular Name: N-(2,6-diethylphenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,6-diethylphenyl)-2-(1,3-dik…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.62 -0.29 -13.37 2 6 0 78 371.481 5 ↓

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-chloro-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 -0.83 -11.85 2 6 0 78 363.845 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-phenyl-acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 -1.17 -14.2 2 6 0 78 315.373 3 ↓

Analogs

4307962
4307962
4307963
4307963
5293191
5293191
3533948
3533948
3543849
3543849

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Popular Name: N-(2,6-dichloro-3-methyl-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,6-dichloro-3-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.49 -1.23 -13.87 2 6 0 78 398.29 3 ↓

Analogs

5342173
5342173
5342175
5342175

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(4-ethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 -1.18 -14.01 2 6 0 78 343.427 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2,5-dimethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 -0.79 -14.03 2 6 0 78 343.427 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2,4-dimethylphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.65 7.55 -14.02 2 6 0 79 343.427 3 ↓

Analogs

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Popular Name: 4-[[2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetyl]amino]benzamide 4-[[2-(1,3-diketo-2,4-diazaspiro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 -4.35 -17.76 4 8 0 121 358.398 4 ↓

Analogs

8658629
8658629

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Popular Name: N-(2,4-dichlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,4-dichlorophenyl)-2-(1,3-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 7.11 -10.55 2 6 0 79 384.263 3 ↓

Analogs

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Popular Name: N-(2,4-dibromophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,4-dibromophenyl)-2-(1,3-dik…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.37 7.35 -10.33 2 6 0 79 473.165 3 ↓

Analogs

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Popular Name: N-(2,3-dichlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,3-dichlorophenyl)-2-(1,3-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.09 -1.76 -11.25 2 6 0 78 384.263 3 ↓

Analogs

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Popular Name: N-(4-chlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-chlorophenyl)-2-(1,3-diketo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.50 -1.81 -13.53 2 6 0 78 349.818 3 ↓

Analogs

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Popular Name: N-(2,6-dichlorophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2,6-dichlorophenyl)-2-(1,3-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.09 -1.55 -13.82 2 6 0 78 384.263 3 ↓

Analogs

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Popular Name: 2-[[2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetyl]amino]benzoic-acid-methyl-ester 2-[[2-(1,3-diketo-2,4-diazaspiro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 -0.17 -13.51 2 8 0 104 373.409 5 ↓

Analogs

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Popular Name: N-(4-acetylphenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-acetylphenyl)-2-(1,3-diketo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 -1.18 -19.96 2 7 0 95 357.41 4 ↓

Analogs

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Popular Name: 2-[[2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetyl]amino]benzoic-acid-ethyl-ester 2-[[2-(1,3-diketo-2,4-diazaspiro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 -0.2 -13.17 2 8 0 104 387.436 6 ↓

Analogs

2619618
2619618

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Popular Name: N-(4-cyanophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(4-cyanophenyl)-2-(1,3-diketo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 -0.28 -15.98 2 7 0 102 340.383 3 ↓

Analogs

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Popular Name: N-(2-bromophenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-bromophenyl)-2-(1,3-diketo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 -2.18 -11.83 2 6 0 78 394.269 3 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(4-methyl-3-nitro-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 -0.94 -14.18 2 9 0 124 374.397 4 ↓

Analogs

3463581
3463581

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Popular Name: N-(2-chloro-5-nitro-phenyl)-2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)acetamide N-(2-chloro-5-nitro-phenyl)-2-(1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.39 -1.11 -16.82 2 9 0 124 394.815 4 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(3,5-dimethoxyphenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 -1.62 -17.05 2 8 0 96 375.425 5 ↓

Analogs

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Popular Name: 2-(1,3-diketo-2,4-diazaspiro[4.6]undecan-2-yl)-N-(2-fluoro-5-nitro-phenyl)acetamide 2-(1,3-diketo-2,4-diazaspiro[4.6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 -0.35 -17.22 2 9 0 124 378.36 4 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
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Structural Results Found: (before additional filtering)

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 245407 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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