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Analogs

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Popular Name: 1-cyclopropyl-2-methyl-benzimidazol-5-amine 1-cyclopropyl-2-methyl-benzimida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.00 5.05 -9.98 2 3 0 44 187.246 1 ↓
Mid Mid (pH 6-8) 1.00 5.48 -24.55 3 3 1 45 188.254 1 ↓

Analogs

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Popular Name: 1-cyclopropyl-2-ethyl-benzimidazol-5-amine 1-cyclopropyl-2-ethyl-benzimidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.51 -9.75 2 3 0 44 201.273 2 ↓
Mid Mid (pH 6-8) 1.57 6.01 -23.22 3 3 1 45 202.281 2 ↓

Analogs

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Popular Name: 1-cyclopropyl-2-propyl-benzimidazol-5-amine 1-cyclopropyl-2-propyl-benzimida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 6.21 -9.69 2 3 0 44 215.3 3 ↓
Mid Mid (pH 6-8) 2.08 6.79 -23.25 3 3 1 45 216.308 3 ↓

Analogs

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Popular Name: 1-cyclopropyl-2-isopropyl-benzimidazol-5-amine 1-cyclopropyl-2-isopropyl-benzim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 6.03 -9.45 2 3 0 44 215.3 2 ↓
Mid Mid (pH 6-8) 2.06 6.61 -21.93 3 3 1 45 216.308 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-cyclopropyl-benzimidazol-5-amine 2-tert-butyl-1-cyclopropyl-benzi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 6.1 -9.96 2 3 0 44 229.327 2 ↓
Mid Mid (pH 6-8) 2.73 6.49 -21.43 3 3 1 45 230.335 2 ↓

Analogs

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Popular Name: 1-cyclopropyl-2-(trifluoromethyl)benzimidazol-5-amine 1-cyclopropyl-2-(trifluoromethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 5.2 -8.63 2 3 0 44 241.216 2 ↓

Analogs

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Popular Name: 1-[(1S,2R)-2-methylcyclopropyl]benzimidazol-5-amine 1-[(1S,2R)-2-methylcyclopropyl]b…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.52 5.4 -8.79 2 3 0 44 187.246 1 ↓
Mid Mid (pH 6-8) 1.52 5.88 -27.67 3 3 1 45 188.254 1 ↓

Analogs

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Popular Name: 1-[(1S,2S)-2-methylcyclopropyl]benzimidazol-5-amine 1-[(1S,2S)-2-methylcyclopropyl]b…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.52 5.73 -8.89 2 3 0 44 187.246 1 ↓
Mid Mid (pH 6-8) 1.52 6.22 -28.27 3 3 1 45 188.254 1 ↓

Analogs

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Popular Name: 1-[(1R,2R)-2-methylcyclopropyl]benzimidazol-5-amine 1-[(1R,2R)-2-methylcyclopropyl]b…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.52 5.74 -8.87 2 3 0 44 187.246 1 ↓
Mid Mid (pH 6-8) 1.52 6.23 -28.26 3 3 1 45 188.254 1 ↓

Analogs

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Popular Name: 1-[(1R,2S)-2-methylcyclopropyl]benzimidazol-5-amine 1-[(1R,2S)-2-methylcyclopropyl]b…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.52 5.39 -8.79 2 3 0 44 187.246 1 ↓
Mid Mid (pH 6-8) 1.52 5.88 -27.66 3 3 1 45 188.254 1 ↓

Analogs

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Popular Name: 2-methyl-1-[(1R,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-methyl-1-[(1R,2S)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.61 5.61 -9.76 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.61 6.05 -24.59 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 2-methyl-1-[(1S,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-methyl-1-[(1S,2S)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.61 5.71 -9.5 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.61 6.15 -24.16 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 2-methyl-1-[(1R,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-methyl-1-[(1R,2R)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.61 5.61 -9.42 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.61 6.05 -24.05 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 2-methyl-1-[(1S,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-methyl-1-[(1S,2R)-2-methylcycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.61 5.53 -9.75 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.61 5.97 -24.44 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 2-ethyl-1-[(1R,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-ethyl-1-[(1R,2S)-2-methylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6 -9.52 2 3 0 44 215.3 2 ↓
Mid Mid (pH 6-8) 2.18 6.58 -23.1 3 3 1 45 216.308 2 ↓

Analogs

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Popular Name: 2-ethyl-1-[(1S,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-ethyl-1-[(1S,2S)-2-methylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6.17 -9.27 2 3 0 44 215.3 2 ↓
Mid Mid (pH 6-8) 2.18 6.64 -22.84 3 3 1 45 216.308 2 ↓

Analogs

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Popular Name: 2-ethyl-1-[(1R,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-ethyl-1-[(1R,2R)-2-methylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6.21 -9.23 2 3 0 44 215.3 2 ↓
Mid Mid (pH 6-8) 2.18 6.54 -23.33 3 3 1 45 216.308 2 ↓

Analogs

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Popular Name: 2-ethyl-1-[(1S,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-ethyl-1-[(1S,2R)-2-methylcyclo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6.13 -9.59 2 3 0 44 215.3 2 ↓
Mid Mid (pH 6-8) 2.18 6.41 -23.13 3 3 1 45 216.308 2 ↓

Analogs

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Popular Name: 1-[(1R,2S)-2-methylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1R,2S)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 6.74 -9.28 2 3 0 44 229.327 3 ↓
Mid Mid (pH 6-8) 2.69 7.35 -23.15 3 3 1 45 230.335 3 ↓

Analogs

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Popular Name: 1-[(1S,2S)-2-methylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1S,2S)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 6.89 -9.32 2 3 0 44 229.327 3 ↓
Mid Mid (pH 6-8) 2.69 7.42 -22.81 3 3 1 45 230.335 3 ↓

Analogs

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Popular Name: 1-[(1R,2R)-2-methylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1R,2R)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 6.98 -9.06 2 3 0 44 229.327 3 ↓
Mid Mid (pH 6-8) 2.69 7.32 -23.3 3 3 1 45 230.335 3 ↓

Analogs

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Popular Name: 1-[(1S,2R)-2-methylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1S,2R)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 6.9 -9.3 2 3 0 44 229.327 3 ↓
Mid Mid (pH 6-8) 2.69 7.19 -23.1 3 3 1 45 230.335 3 ↓

Analogs

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Popular Name: 2-isopropyl-1-[(1S,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-isopropyl-1-[(1S,2R)-2-methylc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 6.58 -9.22 2 3 0 44 229.327 2 ↓
Mid Mid (pH 6-8) 2.67 6.98 -21.8 3 3 1 45 230.335 2 ↓

Analogs

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Popular Name: 2-isopropyl-1-[(1S,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-isopropyl-1-[(1S,2S)-2-methylc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 6.68 -9.01 2 3 0 44 229.327 2 ↓
Mid Mid (pH 6-8) 2.67 7.24 -21.53 3 3 1 45 230.335 2 ↓

Analogs

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Popular Name: 2-isopropyl-1-[(1R,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-isopropyl-1-[(1R,2R)-2-methylc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 6.68 -9.01 2 3 0 44 229.327 2 ↓
Mid Mid (pH 6-8) 2.67 7.13 -21.86 3 3 1 45 230.335 2 ↓

Analogs

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Popular Name: 2-isopropyl-1-[(1R,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-isopropyl-1-[(1R,2S)-2-methylc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 6.58 -9.22 2 3 0 44 229.327 2 ↓
Mid Mid (pH 6-8) 2.67 7.17 -21.84 3 3 1 45 230.335 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1S,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1S,2R)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 6.52 -9.37 2 3 0 44 243.354 2 ↓
Mid Mid (pH 6-8) 3.34 6.91 -21.31 3 3 1 45 244.362 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1S,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1S,2S)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 6.74 -9.51 2 3 0 44 243.354 2 ↓
Mid Mid (pH 6-8) 3.34 7.14 -21.04 3 3 1 45 244.362 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1R,2R)-2-methylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1R,2R)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 6.72 -9.41 2 3 0 44 243.354 2 ↓
Mid Mid (pH 6-8) 3.34 7.13 -20.98 3 3 1 45 244.362 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1R,2S)-2-methylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1R,2S)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 6.5 -9.44 2 3 0 44 243.354 2 ↓
Mid Mid (pH 6-8) 3.34 6.93 -21.31 3 3 1 45 244.362 2 ↓

Analogs

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Popular Name: 1-[(1S,2R)-2-methylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1S,2R)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.53 -8.49 2 3 0 44 255.243 2 ↓

Analogs

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Popular Name: 1-[(1S,2S)-2-methylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1S,2S)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.86 -8.39 2 3 0 44 255.243 2 ↓

Analogs

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Popular Name: 1-[(1R,2R)-2-methylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1R,2R)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.82 -8.4 2 3 0 44 255.243 2 ↓

Analogs

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Popular Name: 1-[(1R,2S)-2-methylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1R,2S)-2-methylcyclopropyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.71 -8.39 2 3 0 44 255.243 2 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 5.9 -8.51 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.48 6.38 -27.88 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 5.89 -8.54 2 3 0 44 201.273 1 ↓
Mid Mid (pH 6-8) 1.48 6.38 -27.86 3 3 1 45 202.281 1 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]-2-methyl-benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 6.56 -24.47 3 3 1 45 216.308 1 ↓
Mid Mid (pH 6-8) 1.57 6.12 -9.34 2 3 0 44 215.3 1 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]-2-methyl-benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 6.49 -24.29 3 3 1 45 216.308 1 ↓
Mid Mid (pH 6-8) 1.57 6.05 -9.36 2 3 0 44 215.3 1 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]-2-ethyl-benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 7.08 -23.01 3 3 1 45 230.335 2 ↓
Mid Mid (pH 6-8) 2.14 6.5 -9.08 2 3 0 44 229.327 2 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]-2-ethyl-benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 6.9 -22.75 3 3 1 45 230.335 2 ↓
Mid Mid (pH 6-8) 2.14 6.65 -9.19 2 3 0 44 229.327 2 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 7.84 -22.93 3 3 1 45 244.362 3 ↓
Mid Mid (pH 6-8) 2.64 7.22 -8.87 2 3 0 44 243.354 3 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]-2-propyl-benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 7.68 -22.68 3 3 1 45 244.362 3 ↓
Mid Mid (pH 6-8) 2.64 7.4 -8.92 2 3 0 44 243.354 3 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]-2-isopropyl-benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.67 -21.59 3 3 1 45 244.362 2 ↓
Mid Mid (pH 6-8) 2.62 7.08 -8.8 2 3 0 44 243.354 2 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]-2-isopropyl-benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.47 -21.42 3 3 1 45 244.362 2 ↓
Mid Mid (pH 6-8) 2.62 7.08 -8.81 2 3 0 44 243.354 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1S)-2,2-dimethylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1S)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 7.41 -21.04 3 3 1 45 258.389 2 ↓
Mid Mid (pH 6-8) 3.29 7.03 -9.13 2 3 0 44 257.381 2 ↓

Analogs

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Popular Name: 2-tert-butyl-1-[(1R)-2,2-dimethylcyclopropyl]benzimidazol-5-amine 2-tert-butyl-1-[(1R)-2,2-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 7.42 -21.03 3 3 1 45 258.389 2 ↓
Mid Mid (pH 6-8) 3.29 7.01 -9.11 2 3 0 44 257.381 2 ↓

Analogs

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Popular Name: 1-[(1S)-2,2-dimethylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1S)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 6.03 -8.32 2 3 0 44 269.27 2 ↓

Analogs

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Popular Name: 1-[(1R)-2,2-dimethylcyclopropyl]-2-(trifluoromethyl)benzimidazol-5-amine 1-[(1R)-2,2-dimethylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 6.39 -8.02 2 3 0 44 269.27 2 ↓

Analogs

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Popular Name: (2S)-2-(1-cyclopropylbenzimidazol-2-yl)pentan-2-amine (2S)-2-(1-cyclopropylbenzimidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 6.8 -44.11 3 3 1 45 244.362 4 ↓
Hi High (pH 8-9.5) 3.22 6.73 -7.58 2 3 0 44 243.354 4 ↓
Lo Low (pH 4.5-6) 3.22 7.19 -97.7 4 3 2 47 245.37 4 ↓

Analogs

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Popular Name: (2R)-2-(1-cyclopropylbenzimidazol-2-yl)pentan-2-amine (2R)-2-(1-cyclopropylbenzimidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 6.67 -46.12 3 3 1 45 244.362 4 ↓
Hi High (pH 8-9.5) 3.22 6.45 -7.89 2 3 0 44 243.354 4 ↓
Lo Low (pH 4.5-6) 3.22 7.05 -99.54 4 3 2 47 245.37 4 ↓

Parameters Provided:

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filter.purchasability = annotated
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Structural Results Found: (before additional filtering)

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