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Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-(trifluoromethyl)pyridine 2-(azetidin-3-yloxy)-6-(trifluor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 2 -39.58 2 3 1 39 219.186 3 ↓
Hi High (pH 8-9.5) 1.70 0.3 -6.22 1 3 0 34 218.178 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-methyl-pyridine-3-carbonitrile 2-(azetidin-3-yloxy)-6-methyl-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.49 2 -41.92 2 4 1 63 190.226 2 ↓
Hi High (pH 8-9.5) 0.49 0.3 -7.81 1 4 0 58 189.218 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-fluoro-pyridine 2-(azetidin-3-yloxy)-3-fluoro-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.84 1.03 -39.29 2 3 1 39 169.179 2 ↓
Hi High (pH 8-9.5) 0.84 -0.67 -6.23 1 3 0 34 168.171 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-methyl-5-nitro-pyridine 2-(azetidin-3-yloxy)-3-methyl-5-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.23 2.37 -45.18 2 6 1 85 210.213 3 ↓
Hi High (pH 8-9.5) 1.23 0.67 -5.56 1 6 0 80 209.205 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-methyl-pyridine 2-(azetidin-3-yloxy)-3-methyl-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.13 1.68 -37.74 2 3 1 39 165.216 2 ↓
Hi High (pH 8-9.5) 1.13 -0.02 -4.97 1 3 0 34 164.208 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3,5-dichloro-pyridine 2-(azetidin-3-yloxy)-3,5-dichlor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 1.99 -39.17 2 3 1 39 220.079 2 ↓
Hi High (pH 8-9.5) 2.18 0.29 -2.81 1 3 0 34 219.071 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)nicotinonitrile hydrochloride 2-(azetidin-3-yloxy)nicotinonitr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.44 1.39 -42.57 2 4 1 63 176.199 2 ↓
Hi High (pH 8-9.5) 0.44 -0.31 -8.26 1 4 0 58 175.191 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-nitro-pyridine 2-(azetidin-3-yloxy)-3-nitro-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.64 2.42 -45.1 2 6 1 85 196.186 3 ↓
Hi High (pH 8-9.5) 0.64 0.72 -9.78 1 6 0 80 195.178 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-methylpyridine dihydrochloride 2-(azetidin-3-yloxy)-6-methylpyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.78 1.55 -37.62 2 3 1 39 165.216 2 ↓
Hi High (pH 8-9.5) 0.78 -0.15 -5.06 1 3 0 34 164.208 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-chloropyridine hydrochloride 2-(azetidin-3-yloxy)-5-chloropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.58 1.44 -38.83 2 3 1 39 185.634 2 ↓
Hi High (pH 8-9.5) 1.58 -0.26 -3.38 1 3 0 34 184.626 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-nitro-pyridine-3-carbonitrile 2-(azetidin-3-yloxy)-5-nitro-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 2.07 -47.02 2 7 1 108 221.196 3 ↓
Hi High (pH 8-9.5) 0.54 0.37 -8.39 1 7 0 104 220.188 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-nitro-pyridine-3-carboxamide 2-(azetidin-3-yloxy)-5-nitro-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.40 -0.29 -45.62 4 8 1 128 239.211 4 ↓
Hi High (pH 8-9.5) -0.40 -1.99 -9.36 3 8 0 123 238.203 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-bromo-3-nitro-pyridine 2-(azetidin-3-yloxy)-5-bromo-3-n…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 3 -42.82 2 6 1 85 275.082 3 ↓
Hi High (pH 8-9.5) 1.60 1.3 -8.34 1 6 0 80 274.074 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-fluoro-pyridine 2-(azetidin-3-yloxy)-5-fluoro-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 1 -39.37 2 3 1 39 169.179 2 ↓
Hi High (pH 8-9.5) 1.06 -0.7 -3.79 1 3 0 34 168.171 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4,6-dimethyl-pyridine-3-carboxamide 2-(azetidin-3-yloxy)-4,6-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.32 -1.21 -42.92 4 5 1 82 222.268 3 ↓
Hi High (pH 8-9.5) 0.32 -2.91 -12.27 3 5 0 77 221.26 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-bromopyridine hydrochloride 2-(azetidin-3-yloxy)-3-bromopyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 1.6 -38.62 2 3 1 39 230.085 2 ↓
Hi High (pH 8-9.5) 1.49 -0.1 -4.98 1 3 0 34 229.077 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-6-methyl-pyridine-3-carboxamide 2-(azetidin-3-yloxy)-6-methyl-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 -0.38 -41.01 4 5 1 82 208.241 3 ↓
Hi High (pH 8-9.5) -0.45 -2.08 -12.76 3 5 0 77 207.233 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)pyridine dihydrochloride 2-(azetidin-3-yloxy)pyridine dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.73 0.95 -37.63 2 3 1 39 151.189 2 ↓
Hi High (pH 8-9.5) 0.73 -0.75 -4.94 1 3 0 34 150.181 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-methylpyridine dihydrochloride 2-(azetidin-3-yloxy)-4-methylpyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.13 1.61 -36.89 2 3 1 39 165.216 2 ↓
Hi High (pH 8-9.5) 1.13 -0.09 -5.99 1 3 0 34 164.208 2 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.51 2.34 -40.41 2 5 1 65 209.225 4 ↓
Hi High (pH 8-9.5) 0.51 0.63 -9.5 1 5 0 60 208.217 4 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4-nitro-pyridine 2-(azetidin-3-yloxy)-4-nitro-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.64 1.66 -44.01 2 6 1 85 196.186 3 ↓
Hi High (pH 8-9.5) 0.64 -0.04 -7.61 1 6 0 80 195.178 3 ↓

Analogs

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Popular Name: 6-(azetidin-3-yloxy)pyridine-3-sulfonamide 6-(azetidin-3-yloxy)pyridine-3-s…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.41 -4.13 -47.52 4 6 1 99 230.269 3 ↓
Hi High (pH 8-9.5) -0.41 -5.83 -10.52 3 6 0 94 229.261 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)pyridine-3-carboxamide 2-(azetidin-3-yloxy)pyridine-3-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.50 -0.98 -41.38 4 5 1 82 194.214 3 ↓
Hi High (pH 8-9.5) -0.50 -2.68 -12.88 3 5 0 77 193.206 3 ↓

Analogs

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Popular Name: 6-(azetidin-3-yloxy)pyridine-3-carboxamide 6-(azetidin-3-yloxy)pyridine-3-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 -2.27 -46.58 4 5 1 82 194.214 3 ↓
Hi High (pH 8-9.5) -0.45 -3.97 -8.52 3 5 0 77 193.206 3 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)pyridine-4-carboxamide 2-(azetidin-3-yloxy)pyridine-4-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.50 -2.28 -43.84 4 5 1 82 194.214 3 ↓
Hi High (pH 8-9.5) -0.50 -3.98 -13.12 3 5 0 77 193.206 3 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.94 2.53 -43.18 2 5 1 65 223.252 5 ↓
Hi High (pH 8-9.5) 0.94 0.82 -5.37 1 5 0 60 222.244 5 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-chloro-5-(trifluoromethyl)pyridine 2-(azetidin-3-yloxy)-3-chloro-5-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.23 2.45 -40.69 2 3 1 39 253.631 3 ↓
Hi High (pH 8-9.5) 2.23 0.75 -2.97 1 3 0 34 252.623 3 ↓

Analogs

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Popular Name: 6-(azetidin-3-yloxy)nicotinonitrile hydrochloride 6-(azetidin-3-yloxy)nicotinonitr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.49 1.34 -43.85 2 4 1 63 176.199 2 ↓
Hi High (pH 8-9.5) 0.49 -0.36 -5.86 1 4 0 58 175.191 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-bromopyridine hydrochloride 2-(azetidin-3-yloxy)-5-bromopyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 1.54 -38.87 2 3 1 39 230.085 2 ↓
Hi High (pH 8-9.5) 1.71 -0.16 -3.31 1 3 0 34 229.077 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-4,6-dimethyl-pyridine-3-carbonitrile 2-(azetidin-3-yloxy)-4,6-dimethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 2.5 -41.79 2 4 1 63 204.253 2 ↓
Hi High (pH 8-9.5) 1.25 0.8 -7.63 1 4 0 58 203.245 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-(trifluoromethyl)pyridine 2-(azetidin-3-yloxy)-3-(trifluor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.58 2.02 -39.84 2 3 1 39 219.186 3 ↓
Hi High (pH 8-9.5) 1.58 0.32 -5.95 1 3 0 34 218.178 3 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.89 3.27 -40.14 2 5 1 65 223.252 5 ↓
Hi High (pH 8-9.5) 0.89 1.57 -9.25 1 5 0 60 222.244 5 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)isonicotinonitrile 2-(azetidin-3-yloxy)isonicotinon…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.44 1.32 -42.35 2 4 1 63 176.199 2 ↓
Hi High (pH 8-9.5) 0.44 -0.38 -7.17 1 4 0 58 175.191 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-5-methyl-pyridine 2-(azetidin-3-yloxy)-5-methyl-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.18 1.59 -37.49 2 3 1 39 165.216 2 ↓
Hi High (pH 8-9.5) 1.18 -0.11 -4.7 1 3 0 34 164.208 2 ↓

Analogs

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Popular Name: 2-(azetidin-3-yloxy)-3-chloropyridine hydrochloride 2-(azetidin-3-yloxy)-3-chloropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 1.49 -38.54 2 3 1 39 185.634 2 ↓
Hi High (pH 8-9.5) 1.36 -0.21 -5.13 1 3 0 34 184.626 2 ↓

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filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 277517 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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