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Analogs

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Popular Name: 7,8-dihydro-5H-1,6-naphthyridin-6-yl-[2-(ethylamino)phenyl]methanone 7,8-dihydro-5H-1,6-naphthyridin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 6.57 -10.04 1 4 0 45 281.359 3 ↓
Lo Low (pH 4.5-6) 1.70 6.97 -37.58 2 4 1 46 282.367 3 ↓

Analogs

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Popular Name: (2-amino-4-fluoro-phenyl)-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)methanone (2-amino-4-fluoro-phenyl)-(7,8-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.09 4.91 -9.51 2 4 0 59 271.295 1 ↓
Lo Low (pH 4.5-6) 1.09 5.3 -38.57 3 4 1 60 272.303 1 ↓

Analogs

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Popular Name: (2-amino-4-chloro-phenyl)-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)methanone (2-amino-4-chloro-phenyl)-(7,8-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 5.36 -9.11 2 4 0 59 287.75 1 ↓
Lo Low (pH 4.5-6) 1.60 5.75 -38.08 3 4 1 60 288.758 1 ↓

Analogs

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Popular Name: (4-amino-3-fluoro-phenyl)-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)methanone (4-amino-3-fluoro-phenyl)-(7,8-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.09 4.68 -14.23 2 4 0 59 271.295 1 ↓
Lo Low (pH 4.5-6) 1.09 5.08 -42.69 3 4 1 60 272.303 1 ↓

Analogs

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Popular Name: 7,8-dihydro-5H-1,6-naphthyridin-6-yl-(3,4,5-trifluorophenyl)methanone 7,8-dihydro-5H-1,6-naphthyridin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 6.89 -10.17 0 3 0 33 292.26 1 ↓
Lo Low (pH 4.5-6) 1.86 7.29 -41.5 1 3 1 34 293.268 1 ↓

Analogs

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Popular Name: 7,8-dihydro-5H-1,6-naphthyridin-6-yl-[2-(methylamino)phenyl]methanone 7,8-dihydro-5H-1,6-naphthyridin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.32 5.75 -10.16 1 4 0 45 267.332 2 ↓
Lo Low (pH 4.5-6) 1.32 6.15 -37.81 2 4 1 46 268.34 2 ↓

Parameters Provided:

ring.id = 281097
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 281097 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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