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Analogs

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Popular Name: 6-bromo-2-(4-methyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 6-bromo-2-(4-methyl-4-piperidyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 4.8 -51.44 3 4 1 58 296.192 1 ↓
Mid Mid (pH 6-8) 2.02 4.32 -56.1 2 4 0 56 295.184 1 ↓

Analogs

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Popular Name: 2-(4-methyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 2-(4-methyl-4-piperidyl)-3H-imid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.07 4.24 -50.99 3 4 1 58 217.296 1 ↓

Analogs

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Popular Name: 6-bromo-2-(4-propyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 6-bromo-2-(4-propyl-4-piperidyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 5.79 -51.65 3 4 1 58 324.246 3 ↓
Mid Mid (pH 6-8) 2.90 6.07 -55.94 2 4 0 56 323.238 3 ↓

Analogs

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Popular Name: 6-bromo-2-(4-ethyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 6-bromo-2-(4-ethyl-4-piperidyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 5.02 -51.2 3 4 1 58 310.219 2 ↓
Mid Mid (pH 6-8) 2.35 5.32 -55.67 2 4 0 56 309.211 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-propyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 2-(4-propyl-4-piperidyl)-3H-imid…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 5.65 -53.6 3 4 1 58 245.35 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-ethyl-4-piperidyl)-3H-imidazo[4,5-b]pyridine 2-(4-ethyl-4-piperidyl)-3H-imida…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 4.89 -53 3 4 1 58 231.323 2 ↓

Parameters Provided:

ring.id = 288090
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 288090 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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