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Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[(6-oxo-1H-pyridazine-3-carbonyl)amino]-2-phenyl-propanoic (2R)-2-[(6-oxo-1H-pyridazine-3-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 2.21 -105.24 1 7 -2 118 285.259 4 ↓
Mid Mid (pH 6-8) 0.39 4.05 -52.38 2 7 -1 115 286.267 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[(6-oxo-1H-pyridazine-3-carbonyl)amino]-2-phenyl-propanoic (2S)-2-[(6-oxo-1H-pyridazine-3-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 2.21 -105.23 1 7 -2 118 285.259 4 ↓
Mid Mid (pH 6-8) 0.39 4.05 -52.38 2 7 -1 115 286.267 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(3-nitrophenyl)methyl]pyridazine-3-carboxamide 6-chloro-N-[(3-nitrophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 4.89 -11.8 1 7 0 101 292.682 4 ↓

Analogs

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Popular Name: 6-amino-N-[(3-nitrophenyl)methyl]pyridazine-3-carboxamide 6-amino-N-[(3-nitrophenyl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.61 3.25 -13.65 3 8 0 127 273.252 4 ↓
Lo Low (pH 4.5-6) 0.61 3.42 -41.68 4 8 1 128 274.26 4 ↓
Lo Low (pH 4.5-6) 0.61 3.47 -40.06 4 8 1 128 274.26 4 ↓

Analogs

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Popular Name: 6-(methylamino)-N-[(3-nitrophenyl)methyl]pyridazine-3-carboxamide 6-(methylamino)-N-[(3-nitropheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.98 4.16 -13.36 2 8 0 113 287.279 5 ↓
Lo Low (pH 4.5-6) 0.98 4.33 -39.27 3 8 1 114 288.287 5 ↓
Lo Low (pH 4.5-6) 0.98 4.38 -38.54 3 8 1 114 288.287 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-hydrazino-N-[(3-nitrophenyl)methyl]pyridazine-3-carboxamide 6-hydrazino-N-[(3-nitrophenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.37 3.11 -14.58 4 9 0 139 288.267 5 ↓
Lo Low (pH 4.5-6) 0.37 3.33 -40.33 5 9 1 140 289.275 5 ↓

Analogs

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Popular Name: N-[[4-(isopropylsulfamoylmethyl)phenyl]methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[[4-(isopropylsulfamoylmethyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.78 -0.33 -45.97 2 8 -1 124 363.419 7 ↓
Lo Low (pH 4.5-6) 0.32 0.49 -19.64 3 8 0 121 364.427 7 ↓

Analogs

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Popular Name: N-[(4-fluoro-3-methyl-phenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(4-fluoro-3-methyl-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 1.99 -36.48 1 5 -1 78 260.248 3 ↓
Lo Low (pH 4.5-6) 1.06 2.81 -10.78 2 5 0 75 261.256 3 ↓

Analogs

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Popular Name: 6-oxo-N-[[2-(trifluoromethoxy)phenyl]methyl]-1H-pyridazine-3-carboxamide 6-oxo-N-[[2-(trifluoromethoxy)ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 1.13 -38.87 1 6 -1 87 312.227 5 ↓
Lo Low (pH 4.5-6) 1.44 1.95 -10.84 2 6 0 84 313.235 5 ↓

Analogs

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Popular Name: N-[(2-fluorophenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(2-fluorophenyl)methyl]-N-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.33 2.7 -45.71 0 5 -1 69 260.248 3 ↓
Mid Mid (pH 6-8) 0.88 4.54 -12.12 1 5 0 66 261.256 3 ↓

Analogs

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Popular Name: N-[(2,4-dimethoxyphenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(2,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 2.39 -38.1 0 7 -1 88 302.31 5 ↓
Lo Low (pH 4.5-6) 0.80 3.21 -11.38 1 7 0 85 303.318 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2,3-dimethoxyphenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(2,3-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.04 2.93 -39.47 0 7 -1 88 302.31 5 ↓
Lo Low (pH 4.5-6) 0.58 3.75 -11.7 1 7 0 85 303.318 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(2-methoxyphenyl)ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1R)-1-(2-methoxyphenyl)ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 1.53 -39.63 1 6 -1 87 272.284 4 ↓
Lo Low (pH 4.5-6) 1.08 2.35 -12.35 2 6 0 84 273.292 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-(2-methoxyphenyl)ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1S)-1-(2-methoxyphenyl)ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 1.55 -39.73 1 6 -1 87 272.284 4 ↓
Lo Low (pH 4.5-6) 1.08 2.37 -12.4 2 6 0 84 273.292 4 ↓

Analogs

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Popular Name: N-methyl-N-[(4-methylsulfanylphenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-methyl-N-[(4-methylsulfanylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 4.61 -37.58 0 5 -1 69 288.352 4 ↓
Lo Low (pH 4.5-6) 1.19 5.44 -11.89 1 5 0 66 289.36 4 ↓

Analogs

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Popular Name: N-[(4-ethoxyphenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(4-ethoxyphenyl)methyl]-N-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 3.83 -37.04 0 6 -1 78 286.311 5 ↓
Lo Low (pH 4.5-6) 1.19 4.65 -11.4 1 6 0 75 287.319 5 ↓

Analogs

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Popular Name: N-[(3-fluorophenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(3-fluorophenyl)methyl]-N-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.64 -38.03 0 5 -1 69 260.248 3 ↓
Lo Low (pH 4.5-6) 0.90 4.46 -12.76 1 5 0 66 261.256 3 ↓

Analogs

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Popular Name: N-methyl-N-(o-tolylmethyl)-6-oxo-1H-pyridazine-3-carboxamide N-methyl-N-(o-tolylmethyl)-6-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 3.85 -42.47 0 5 -1 69 256.285 3 ↓
Mid Mid (pH 6-8) 1.16 5.69 -9.69 1 5 0 66 257.293 3 ↓

Analogs

31329510
31329510

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Popular Name: N-[[4-(difluoromethoxy)phenyl]methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 2.24 -45.94 0 6 -1 78 308.264 5 ↓
Mid Mid (pH 6-8) 1.37 4.08 -13.53 1 6 0 75 309.272 5 ↓

Analogs

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Popular Name: N-[(4-methoxyphenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(4-methoxyphenyl)methyl]-N-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 1.95 -42.98 0 6 -1 78 272.284 4 ↓
Mid Mid (pH 6-8) 0.82 3.8 -10.89 1 6 0 75 273.292 4 ↓

Analogs

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Popular Name: N-ethyl-N-[(3-fluoro-4-methoxy-phenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-ethyl-N-[(3-fluoro-4-methoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 4.2 -39.51 0 6 -1 78 304.301 5 ↓
Lo Low (pH 4.5-6) 1.28 5.02 -12.67 1 6 0 75 305.309 5 ↓

Analogs

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Popular Name: N-[(4-dimethylaminophenyl)methyl]-N-methyl-6-oxo-1H-pyridazine-3-carboxamide N-[(4-dimethylaminophenyl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.32 3.06 -43.62 0 6 -1 72 285.327 4 ↓
Mid Mid (pH 6-8) 0.86 4.92 -10.49 1 6 0 69 286.335 4 ↓
Lo Low (pH 4.5-6) 0.86 5.67 -22.57 2 6 0 70 287.343 4 ↓

Analogs

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Popular Name: 6-oxo-N-[(2,4,5-trimethoxyphenyl)methyl]-1H-pyridazine-3-carboxamide 6-oxo-N-[(2,4,5-trimethoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 -0.12 -41.63 1 8 -1 106 318.309 6 ↓
Lo Low (pH 4.5-6) 0.15 0.71 -13.97 2 8 0 103 319.317 6 ↓

Analogs

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Popular Name: N-[(1R)-1-(2,5-dimethoxyphenyl)ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1R)-1-(2,5-dimethoxyphenyl)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 0.83 -41.74 1 7 -1 96 302.31 5 ↓
Lo Low (pH 4.5-6) 1.12 1.65 -12.22 2 7 0 93 303.318 5 ↓

Analogs

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Popular Name: N-[(1S)-1-(2,5-dimethoxyphenyl)ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1S)-1-(2,5-dimethoxyphenyl)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 0.85 -41.69 1 7 -1 96 302.31 5 ↓
Lo Low (pH 4.5-6) 1.12 1.67 -12.35 2 7 0 93 303.318 5 ↓

Analogs

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-N-ethyl-6-oxo-1H-pyridazine-3-carboxamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.24 3.9 -41.35 0 7 -1 88 316.337 6 ↓
Lo Low (pH 4.5-6) 0.78 4.72 -14.53 1 7 0 85 317.345 6 ↓

Analogs

31993651
31993651

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Popular Name: 6-oxo-N-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyridazine-3-carboxamide 6-oxo-N-[(3,4,5-trimethoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 0.42 -39.79 1 8 -1 106 318.309 6 ↓
Lo Low (pH 4.5-6) 0.15 1.24 -14.96 2 8 0 103 319.317 6 ↓

Analogs

8762684
8762684
36727650
36727650
37863462
37863462
37986559
37986559

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Popular Name: 6-[(4-methylbenzyl)carbamoyl]pyridazin-3-olate 6-[(4-methylbenzyl)carbamoyl]pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.42 0.97 -40.67 1 5 -1 78 242.258 3 ↓

Analogs

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Popular Name: 6-[(2-chlorobenzyl)carbamoyl]pyridazin-3-olate 6-[(2-chlorobenzyl)carbamoyl]pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 0.7 -42.02 1 5 -1 78 262.676 3 ↓
Mid Mid (pH 6-8) 1.60 -3.49 -14.24 2 5 0 75 263.684 3 ↓

Analogs

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Popular Name: N-[(1S)-2-hydroxy-1-phenyl-ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1S)-2-hydroxy-1-phenyl-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.52 -2.04 -42.8 2 6 -1 98 258.257 4 ↓
Lo Low (pH 4.5-6) 0.07 -0.2 -9.02 3 6 0 95 259.265 4 ↓

Analogs

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Popular Name: N-[(1R)-2-hydroxy-1-phenyl-ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1R)-2-hydroxy-1-phenyl-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.52 -2.04 -42.82 2 6 -1 98 258.257 4 ↓
Lo Low (pH 4.5-6) 0.07 -0.2 -9.01 3 6 0 95 259.265 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-chloro-N-[(1S)-2-hydroxy-1-phenyl-ethyl]pyridazine-3-carboxamide 6-chloro-N-[(1S)-2-hydroxy-1-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.42 1.85 -7.87 2 5 0 75 277.711 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-2-hydroxy-1-phenyl-ethyl]pyridazine-3-carboxamide 6-chloro-N-[(1R)-2-hydroxy-1-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.42 1.85 -7.88 2 5 0 75 277.711 4 ↓

Analogs

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Popular Name: N-[(3-chlorophenyl)methyl]-N-propyl-pyridazine-3-carboxamide N-[(3-chlorophenyl)methyl]-N-pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 8.54 -9.73 0 4 0 46 289.766 5 ↓

Analogs

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Popular Name: N-butyl-N-[(2-fluorophenyl)methyl]pyridazine-3-carboxamide N-butyl-N-[(2-fluorophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.45 8.85 -11.35 0 4 0 46 287.338 6 ↓

Analogs

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Popular Name: 6-(dimethylamino)-N-[(1S)-1-(2-methoxyphenyl)ethyl]pyridazine-3-carboxamide 6-(dimethylamino)-N-[(1S)-1-(2-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 5.64 -33.19 2 6 1 69 301.37 5 ↓
Mid Mid (pH 6-8) 1.86 5.55 -10.83 1 6 0 67 300.362 5 ↓
Lo Low (pH 4.5-6) 1.86 5.78 -32.31 2 6 1 69 301.37 5 ↓

Analogs

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Popular Name: 6-(dimethylamino)-N-[(1R)-1-(2-methoxyphenyl)ethyl]pyridazine-3-carboxamide 6-(dimethylamino)-N-[(1R)-1-(2-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 5.62 -33.07 2 6 1 69 301.37 5 ↓
Mid Mid (pH 6-8) 1.86 5.53 -10.78 1 6 0 67 300.362 5 ↓
Lo Low (pH 4.5-6) 1.86 5.77 -32.27 2 6 1 69 301.37 5 ↓

Analogs

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Popular Name: 6-oxo-N-[(1S)-1-phenylhexyl]-1H-pyridazine-3-carboxamide 6-oxo-N-[(1S)-1-phenylhexyl]-1H-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 4.64 -41.21 1 5 -1 78 298.366 7 ↓
Mid Mid (pH 6-8) 2.24 6.48 -8.75 2 5 0 75 299.374 7 ↓

Analogs

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Popular Name: 6-oxo-N-[(1R)-1-phenylhexyl]-1H-pyridazine-3-carboxamide 6-oxo-N-[(1R)-1-phenylhexyl]-1H-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 4.63 -41.21 1 5 -1 78 298.366 7 ↓
Mid Mid (pH 6-8) 2.24 6.47 -8.8 2 5 0 75 299.374 7 ↓

Analogs

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Popular Name: N-ethyl-N-[(3-fluorophenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-ethyl-N-[(3-fluorophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 3.87 -44.26 0 5 -1 69 274.275 4 ↓
Mid Mid (pH 6-8) 1.27 5.71 -11.81 1 5 0 66 275.283 4 ↓

Analogs

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Popular Name: N-[(2-chloro-4-fluoro-phenyl)methyl]-N-(2-methoxyethyl)-6-oxo-1H-pyridazine-3-carboxamide N-[(2-chloro-4-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 3.84 -46.55 0 6 -1 78 338.746 6 ↓
Mid Mid (pH 6-8) 1.51 5.7 -12.09 1 6 0 75 339.754 6 ↓

Analogs

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Popular Name: N-[(1R)-1-(3,4-dichlorophenyl)butyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1R)-1-(3,4-dichlorophenyl)bu…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 3.46 -39.51 1 5 -1 78 339.202 5 ↓
Lo Low (pH 4.5-6) 2.52 5.31 -9.22 2 5 0 75 340.21 5 ↓

Analogs

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Popular Name: N-[(4-methylsulfanylphenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(4-methylsulfanylphenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.41 1.32 -41.12 1 5 -1 78 274.325 4 ↓
Lo Low (pH 4.5-6) 0.95 3.16 -9.16 2 5 0 75 275.333 4 ↓

Analogs

31331128
31331128
31331131
31331131

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Popular Name: N-[(1R)-1-(3,4-dichlorophenyl)ethyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1R)-1-(3,4-dichlorophenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 2.09 -39.33 1 5 -1 78 311.148 3 ↓
Lo Low (pH 4.5-6) 2.36 3.94 -9.63 2 5 0 75 312.156 3 ↓

Analogs

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Popular Name: N-[(4-bromo-2-chloro-phenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(4-bromo-2-chloro-phenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 1.37 -40.67 1 5 -1 78 341.572 3 ↓
Lo Low (pH 4.5-6) 1.93 3.21 -8.46 2 5 0 75 342.58 3 ↓

Analogs

31745929
31745929
31993651
31993651

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Popular Name: N-[(3-hydroxy-4-methoxy-phenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(3-hydroxy-4-methoxy-phenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.31 -2.57 -43.98 2 7 -1 107 274.256 4 ↓
Lo Low (pH 4.5-6) -0.15 -0.73 -11.64 3 7 0 104 275.264 4 ↓

Analogs

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Popular Name: N-[(3-nitrophenyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(3-nitrophenyl)methyl]-6-oxo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.91 1 -44.58 1 8 -1 124 273.228 4 ↓
Lo Low (pH 4.5-6) 0.45 2.85 -13.81 2 8 0 121 274.236 4 ↓

Analogs

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Popular Name: 3-[[(6-oxo-1H-pyridazine-3-carbonyl)amino]methyl]benzoic 3-[[(6-oxo-1H-pyridazine-3-carbo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.86 0.85 -98.17 1 7 -2 118 271.232 4 ↓
Lo Low (pH 4.5-6) 0.40 2.69 -53.16 2 7 -1 115 272.24 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(3,4-difluorophenyl)methyl]pyridazine-3-carboxamide 6-chloro-N-[(3,4-difluorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 4.3 -8.9 1 4 0 55 283.665 3 ↓

Parameters Provided:

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