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ZINC Item

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52879519

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-methyl-3-(m-tolyl)-5-phenyl-imidazolidine-2,4-dione (5R)-5-methyl-3-(m-tolyl)-5-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.33	7.63	-8.68	1	4	0	49	280.327	2	↓ MOL2 SDF SMILES Flexibase

52879521

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-methyl-3-(m-tolyl)-5-phenyl-imidazolidine-2,4-dione (5S)-5-methyl-3-(m-tolyl)-5-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.33	7.63	-8.65	1	4	0	49	280.327	2	↓ MOL2 SDF SMILES Flexibase

52879523

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	7.51	-6.84	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879526

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	7.51	-6.81	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879531

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-methyl-5-phenyl-3-(p-tolyl)imidazolidine-2,4-dione (5R)-5-methyl-5-phenyl-3-(p-toly…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.35	7.64	-8.41	1	4	0	49	280.327	2	↓ MOL2 SDF SMILES Flexibase

52879534

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-methyl-5-phenyl-3-(p-tolyl)imidazolidine-2,4-dione (5S)-5-methyl-5-phenyl-3-(p-toly…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.35	7.64	-8.46	1	4	0	49	280.327	2	↓ MOL2 SDF SMILES Flexibase

52879535

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-methyl-3,5-diphenyl-imidazolidine-2,4-dione (5S)-5-methyl-3,5-diphenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	6.99	-8.49	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

52879538

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-methyl-3,5-diphenyl-imidazolidine-2,4-dione (5R)-5-methyl-3,5-diphenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	6.99	-8.5	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

52879539

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	7.06	-7.06	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879541

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	7.06	-7.05	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879543

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	7.23	-12.08	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879545

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(2-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	7.24	-12.77	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879546

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	7.5	-7.88	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879549

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	7.5	-7.9	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879555

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	7.92	-10.96	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879557

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(2-chlorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	7.92	-11.43	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

52879559

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.04	7.06	-8.35	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879561

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3-fluorophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3-fluorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.04	7.06	-8.47	1	4	0	49	284.29	2	↓ MOL2 SDF SMILES Flexibase

52879562

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-aminophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-aminophenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.86	-9.09	3	5	0	75	281.315	2	↓ MOL2 SDF SMILES Flexibase

52879564

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-aminophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-aminophenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.86	-9.04	3	5	0	75	281.315	2	↓ MOL2 SDF SMILES Flexibase

52879566

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3-aminophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3-aminophenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.95	4.87	-9.35	3	5	0	75	281.315	2	↓ MOL2 SDF SMILES Flexibase

52879568

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3-aminophenyl)-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3-aminophenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.95	4.87	-9.31	3	5	0	75	281.315	2	↓ MOL2 SDF SMILES Flexibase

36756441

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(4R)-2,5-dioxo-4-phenyl-imidazolidin-1-yl]benzonitrile 3-[(4R)-2,5-dioxo-4-phenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.19	6.9	-10.42	1	5	0	73	277.283	2	↓ MOL2 SDF SMILES Flexibase

36756442

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(4S)-2,5-dioxo-4-phenyl-imidazolidin-1-yl]benzonitrile 3-[(4S)-2,5-dioxo-4-phenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.19	6.9	-10.38	1	5	0	73	277.283	2	↓ MOL2 SDF SMILES Flexibase

36756443

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4R)-2,5-dioxo-4-phenyl-imidazolidin-1-yl]benzonitrile 4-[(4R)-2,5-dioxo-4-phenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.92	-9.27	1	5	0	73	277.283	2	↓ MOL2 SDF SMILES Flexibase

36756444

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4S)-2,5-dioxo-4-phenyl-imidazolidin-1-yl]benzonitrile 4-[(4S)-2,5-dioxo-4-phenyl-imida…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.91	-9.3	1	5	0	73	277.283	2	↓ MOL2 SDF SMILES Flexibase

36756445

Analogs

13680144

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-methoxyphenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-methoxyphenyl)-5-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	5.84	-9.13	1	5	0	59	282.299	3	↓ MOL2 SDF SMILES Flexibase

36756446

Analogs

13680144

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-methoxyphenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-methoxyphenyl)-5-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	5.85	-9.13	1	5	0	59	282.299	3	↓ MOL2 SDF SMILES Flexibase

36756447

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	7.03	-8.36	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

36756448

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	7.03	-8.34	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

36756449

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3-chloro-4-methyl-phenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3-chloro-4-methyl-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	7.65	-8.37	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

36756450

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3-chloro-4-methyl-phenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3-chloro-4-methyl-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	7.66	-8.39	1	4	0	49	300.745	2	↓ MOL2 SDF SMILES Flexibase

36756451

Analogs

33000582
33000585

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2-methoxyphenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2-methoxyphenyl)-5-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.1	-13.44	1	5	0	59	282.299	3	↓ MOL2 SDF SMILES Flexibase

36756452

Analogs

33000582
33000585

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(2-methoxyphenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2-methoxyphenyl)-5-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.11	-13.16	1	5	0	59	282.299	3	↓ MOL2 SDF SMILES Flexibase

36756453

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(m-tolyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(m-tolyl)-5-phenyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.88	7.22	-9.06	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

36756454

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(m-tolyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(m-tolyl)-5-phenyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.88	7.23	-9.05	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

36756455

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(2-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.08	7.44	-11.81	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

36756456

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.08	7.44	-11.23	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

36756457

Analogs

13679316

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(2,4-difluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2,4-difluorophenyl)-5-ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.71	6.83	-11.05	1	4	0	49	288.253	2	↓ MOL2 SDF SMILES Flexibase

36756458

Analogs

13679316

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2,4-difluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2,4-difluorophenyl)-5-ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.71	6.83	-10.17	1	4	0	49	288.253	2	↓ MOL2 SDF SMILES Flexibase

36756459

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-phenyl-3-(p-tolyl)imidazolidine-2,4-dione (5S)-5-phenyl-3-(p-tolyl)imidazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	7.23	-8.85	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

36756460

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-phenyl-3-(p-tolyl)imidazolidine-2,4-dione (5R)-5-phenyl-3-(p-tolyl)imidazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	7.24	-8.83	1	4	0	49	266.3	2	↓ MOL2 SDF SMILES Flexibase

36756461

Analogs

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Popular Name: (5R)-3-(2-fluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(2-fluorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	6.76	-13.18	1	4	0	49	270.263	2	↓ MOL2 SDF SMILES Flexibase

36756462

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(2-fluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(2-fluorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	6.76	-12.42	1	4	0	49	270.263	2	↓ MOL2 SDF SMILES Flexibase

36756463

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-fluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-fluorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.62	6.59	-7.62	1	4	0	49	270.263	2	↓ MOL2 SDF SMILES Flexibase

36756464

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-fluorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-fluorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.62	6.59	-7.65	1	4	0	49	270.263	2	↓ MOL2 SDF SMILES Flexibase

36756467

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(3,4-dichlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(3,4-dichlorophenyl)-5-ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.74	7.49	-7.37	1	4	0	49	321.163	2	↓ MOL2 SDF SMILES Flexibase

36756468

Analogs

13680136

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(3,4-dichlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(3,4-dichlorophenyl)-5-ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.74	7.49	-7.38	1	4	0	49	321.163	2	↓ MOL2 SDF SMILES Flexibase

36756469

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-(4-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5R)-3-(4-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.13	7.04	-7.43	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

36756470

Analogs

13679314

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-(4-chlorophenyl)-5-phenyl-imidazolidine-2,4-dione (5S)-3-(4-chlorophenyl)-5-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.13	7.04	-7.45	1	4	0	49	286.718	2	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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Embed Link to Results

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