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Popular Name: 6-bromo-2-[(3S)-3-methylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3S)-3-methylpyrrolid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.27 -47.32 3 4 1 58 282.165 1 ↓
Mid Mid (pH 6-8) 2.10 3.8 -47.92 2 4 0 56 281.157 1 ↓

Analogs

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Popular Name: 6-bromo-2-[(3R)-3-methylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3R)-3-methylpyrrolid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.41 -44.96 3 4 1 58 282.165 1 ↓
Mid Mid (pH 6-8) 2.10 3.92 -46.04 2 4 0 56 281.157 1 ↓

Analogs

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Popular Name: 6-bromo-2-[(3S)-3-ethylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3S)-3-ethylpyrrolidi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 4.98 -47.92 3 4 1 58 296.192 2 ↓
Mid Mid (pH 6-8) 2.43 4.81 -47.58 2 4 0 56 295.184 2 ↓

Analogs

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Popular Name: 6-bromo-2-[(3R)-3-ethylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3R)-3-ethylpyrrolidi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 4.68 -45.74 3 4 1 58 296.192 2 ↓
Mid Mid (pH 6-8) 2.43 4.94 -45.66 2 4 0 56 295.184 2 ↓

Analogs

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Popular Name: 6-bromo-2-[(3S)-3-propylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3S)-3-propylpyrrolid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 5.73 -48.55 3 4 1 58 310.219 3 ↓
Mid Mid (pH 6-8) 2.98 5.58 -47.67 2 4 0 56 309.211 3 ↓

Analogs

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Popular Name: 6-bromo-2-[(3R)-3-propylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 6-bromo-2-[(3R)-3-propylpyrrolid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 5.44 -46.21 3 4 1 58 310.219 3 ↓
Mid Mid (pH 6-8) 2.98 5.69 -45.64 2 4 0 56 309.211 3 ↓

Analogs

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Popular Name: 2-[(3S)-3-methylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3S)-3-methylpyrrolidin-3-yl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 3.68 -47.65 3 4 1 58 203.269 1 ↓
Mid Mid (pH 6-8) 1.15 4.03 -96.67 4 4 2 59 204.277 1 ↓

Analogs

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Popular Name: 2-[(3R)-3-methylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3R)-3-methylpyrrolidin-3-yl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 3.83 -45.19 3 4 1 58 203.269 1 ↓
Mid Mid (pH 6-8) 1.15 4.13 -96.65 4 4 2 59 204.277 1 ↓

Analogs

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Popular Name: 2-[(3S)-3-ethylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3S)-3-ethylpyrrolidin-3-yl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 4.4 -48.29 3 4 1 58 217.296 2 ↓

Analogs

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Popular Name: 2-[(3R)-3-ethylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3R)-3-ethylpyrrolidin-3-yl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 4.09 -45.86 3 4 1 58 217.296 2 ↓

Analogs

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Popular Name: 2-[(3S)-3-propylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3S)-3-propylpyrrolidin-3-yl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 5.14 -48.81 3 4 1 58 231.323 3 ↓

Analogs

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Popular Name: 2-[(3R)-3-propylpyrrolidin-3-yl]-3H-imidazo[4,5-b]pyridine 2-[(3R)-3-propylpyrrolidin-3-yl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 4.85 -46.29 3 4 1 58 231.323 3 ↓

Parameters Provided:

ring.id = 307830
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 307830 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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