ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

452

Analogs

2041300

Draw Identity 99% 90% 80% 70%

Popular Name: 5-((2-Methoxyphenoxy)methyl)oxazolidin-2-one 5-((2-Methoxyphenoxy)methyl)oxaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.09	1.74	-17.2	1	5	0	57	223.228	4	↓ MOL2 SDF SMILES Flexibase

471

Analogs

897322

Draw Identity 99% 90% 80% 70%

Popular Name: Metaxalone Metaxalone

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.30	3.13	-14.37	1	4	0	48	221.256	3	↓ MOL2 SDF SMILES Flexibase
Ref Reference (pH 7)	1.93	-1.15	-8.25	1	4	0	51	221.256	3	↓ MOL2 SDF SMILES Flexibase

35625865

Analogs

43460732
43460733
43460734
43460735

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1S)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1S)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.01	-15.12	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35625866

Analogs

43460732
43460733
43460734
43460735

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1R)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1R)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.01	-15.85	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35625867

Analogs

43460732
43460733
43460734
43460735

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1S)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1S)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.01	-15.88	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35625868

Analogs

43460732
43460733
43460734
43460735

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1R)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1R)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.01	-15.1	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35626267

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	-0	-16.69	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626268

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	-0.04	-16.43	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626269

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	-0	-16.51	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626270

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	-0.04	-16.62	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626577

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1S)-1-hydroxyethyl]-2-methoxy-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.63	-0.07	-18.07	2	6	0	77	267.281	5	↓ MOL2 SDF SMILES Flexibase

35626578

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1R)-1-hydroxyethyl]-2-methoxy-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.63	-0.11	-18.31	2	6	0	77	267.281	5	↓ MOL2 SDF SMILES Flexibase

35626579

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1S)-1-hydroxyethyl]-2-methoxy-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.63	-0.07	-18.23	2	6	0	77	267.281	5	↓ MOL2 SDF SMILES Flexibase

35626580

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1R)-1-hydroxyethyl]-2-methoxy-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.63	-0.11	-18.11	2	6	0	77	267.281	5	↓ MOL2 SDF SMILES Flexibase

35626945

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	0.1	-15.44	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626948

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	0.09	-15.83	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626949

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	0.1	-15.83	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35626952

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	0.09	-15.46	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35627338

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(3S)-3-hydroxybutyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(3S)-3-hydroxybutyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.91	1.52	-15.26	2	5	0	68	265.309	6	↓ MOL2 SDF SMILES Flexibase

35627339

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(3R)-3-hydroxybutyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(3R)-3-hydroxybutyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.91	1.52	-16	2	5	0	68	265.309	6	↓ MOL2 SDF SMILES Flexibase

35627340

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(3S)-3-hydroxybutyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(3S)-3-hydroxybutyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.91	1.52	-15.28	2	5	0	68	265.309	6	↓ MOL2 SDF SMILES Flexibase

35627341

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(3R)-3-hydroxybutyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(3R)-3-hydroxybutyl]…

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Activity (Go SEA)

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.91	1.52	-16.06	2	5	0	68	265.309	6	↓ MOL2 SDF SMILES Flexibase

35627715

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[3-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[3-[(1S)-1-hydroxyethyl]…

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Activity (Go SEA)

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.02	-0.01	-15.78	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35627716

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[3-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[3-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.02	-0.05	-16.03	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35627717

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[3-[(1S)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[3-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.02	-0.01	-15.95	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35627718

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[3-[(1R)-1-hydroxyethyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[3-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.02	-0.05	-15.82	2	5	0	68	237.255	4	↓ MOL2 SDF SMILES Flexibase

35628257

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1S)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1S)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	0.92	-15.48	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35628258

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-[(1R)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-[(1R)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	0.88	-15.18	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35628259

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1S)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1S)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	0.92	-15.25	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35628260

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-[(1R)-1-hydroxypropyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-[(1R)-1-hydroxypropyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	0.88	-15.46	2	5	0	68	251.282	5	↓ MOL2 SDF SMILES Flexibase

35630052

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1R)-1-hydroxyethyl]-4-methyl-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.42	0.76	-15.93	2	5	0	68	251.282	4	↓ MOL2 SDF SMILES Flexibase

35630054

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-[(1S)-1-hydroxyethyl]-4-methyl-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.42	0.77	-15.53	2	5	0	68	251.282	4	↓ MOL2 SDF SMILES Flexibase

35630056

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1R)-1-hydroxyethyl]-4-methyl-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1R)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.42	0.76	-15.57	2	5	0	68	251.282	4	↓ MOL2 SDF SMILES Flexibase

35630058

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-[(1S)-1-hydroxyethyl]-4-methyl-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-[(1S)-1-hydroxyethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.42	0.77	-15.9	2	5	0	68	251.282	4	↓ MOL2 SDF SMILES Flexibase

37093943

Analogs

42876813
42876817

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-(hydroxymethyl)-4-methoxy-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-(hydroxymethyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.80	-1.36	-17.98	2	6	0	77	253.254	5	↓ MOL2 SDF SMILES Flexibase

37093944

Analogs

42876813
42876817

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-(hydroxymethyl)-4-methoxy-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-(hydroxymethyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.80	-1.36	-17.99	2	6	0	77	253.254	5	↓ MOL2 SDF SMILES Flexibase

58552939

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-bromo-4-[[(5S)-2-oxooxazolidin-5-yl]methoxy]benzoic 3-bromo-4-[[(5S)-2-oxooxazolidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.12	3.04	-56.93	1	6	-1	88	315.099	4	↓ MOL2 SDF SMILES Flexibase

58552940

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-bromo-4-[[(5R)-2-oxooxazolidin-5-yl]methoxy]benzoic 3-bromo-4-[[(5R)-2-oxooxazolidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.12	3.04	-56.94	1	6	-1	88	315.099	4	↓ MOL2 SDF SMILES Flexibase

63235343

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-bromo-4-[[(5S)-2-oxooxazolidin-5-yl]methoxy]benzaldehyde 3-bromo-4-[[(5S)-2-oxooxazolidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	2.22	-22.8	1	5	0	65	300.108	4	↓ MOL2 SDF SMILES Flexibase

63235345

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-bromo-4-[[(5R)-2-oxooxazolidin-5-yl]methoxy]benzaldehyde 3-bromo-4-[[(5R)-2-oxooxazolidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	2.22	-22.8	1	5	0	65	300.108	4	↓ MOL2 SDF SMILES Flexibase

48794925

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-bromo-6-(ethylaminomethyl)phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-bromo-6-(ethylaminome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	3.36	-42.21	3	5	1	64	330.202	6	↓ MOL2 SDF SMILES Flexibase

48794927

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-bromo-6-(ethylaminomethyl)phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-bromo-6-(ethylaminome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	3.36	-55.48	3	5	1	64	330.202	6	↓ MOL2 SDF SMILES Flexibase

48795247

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[2-bromo-6-(propylaminomethyl)phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-bromo-6-(propylaminom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.63	4.11	-43.06	3	5	1	64	344.229	7	↓ MOL2 SDF SMILES Flexibase

48795249

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-bromo-6-(propylaminomethyl)phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-bromo-6-(propylaminom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.63	4.11	-56.33	3	5	1	64	344.229	7	↓ MOL2 SDF SMILES Flexibase

48795534

Analogs

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Popular Name: (5S)-5-[[2-bromo-6-[(isopropylamino)methyl]phenoxy]methyl]oxazolidin-2-one (5S)-5-[[2-bromo-6-[(isopropylam…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	3.88	-41.35	3	5	1	64	344.229	6	↓ MOL2 SDF SMILES Flexibase

48795536

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[2-bromo-6-[(isopropylamino)methyl]phenoxy]methyl]oxazolidin-2-one (5R)-5-[[2-bromo-6-[(isopropylam…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	3.88	-53.8	3	5	1	64	344.229	6	↓ MOL2 SDF SMILES Flexibase

37226444

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methoxy-2-nitro-4-[[(5S)-2-oxooxazolidin-5-yl]methoxy]benzaldehyde 5-methoxy-2-nitro-4-[[(5S)-2-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.74	2.11	-17.73	1	9	0	120	296.235	6	↓ MOL2 SDF SMILES Flexibase

37226445

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methoxy-2-nitro-4-[[(5R)-2-oxooxazolidin-5-yl]methoxy]benzaldehyde 5-methoxy-2-nitro-4-[[(5R)-2-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.74	2.11	-17.85	1	9	0	120	296.235	6	↓ MOL2 SDF SMILES Flexibase

37226536

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-[[4-(hydroxymethyl)-2-methoxy-5-nitro-phenoxy]methyl]oxazolidin-2-one (5S)-5-[[4-(hydroxymethyl)-2-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.29	-0.2	-17.69	2	9	0	123	298.251	6	↓ MOL2 SDF SMILES Flexibase

37226537

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-[[4-(hydroxymethyl)-2-methoxy-5-nitro-phenoxy]methyl]oxazolidin-2-one (5R)-5-[[4-(hydroxymethyl)-2-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.29	-0.2	-17.67	2	9	0	123	298.251	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
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Structural Results Found: (before additional filtering)

SQL Query Was

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Embed Link to Results

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<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
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