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Analogs

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Popular Name: 2-[cyclopropylmethyl(ethyl)amino]imidazo[1,2-a]pyridine-3-carbaldehyde 2-[cyclopropylmethyl(ethyl)amino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 9.46 -10.2 0 4 0 38 243.31 5 ↓

Analogs

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Popular Name: [2-[cyclopropylmethyl(ethyl)amino]imidazo[1,2-a]pyridin-3-yl]methanol [2-[cyclopropylmethyl(ethyl)amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 7.04 -11.61 1 4 0 41 245.326 5 ↓
Mid Mid (pH 6-8) 2.35 7.7 -24.41 2 4 1 42 246.334 5 ↓
Mid Mid (pH 6-8) 2.35 6.67 -31.43 2 4 1 42 246.334 5 ↓

Analogs

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Popular Name: 3-(chloromethyl)-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-(chloromethyl)-N-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 10.71 -8.58 0 3 0 21 263.772 5 ↓
Lo Low (pH 4.5-6) 3.59 11.35 -25.19 1 3 1 22 264.78 5 ↓
Lo Low (pH 4.5-6) 3.59 10.72 -28.88 1 3 1 22 264.78 5 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-N-ethyl-3-(propylaminomethyl)imidazo[1,2-a]pyridin-2-amine N-(cyclopropylmethyl)-N-ethyl-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 10.96 -107.85 3 4 2 38 288.439 8 ↓
Hi High (pH 8-9.5) 3.45 9.81 -7.67 1 4 0 33 286.423 8 ↓
Mid Mid (pH 6-8) 3.45 11.17 -46.64 2 4 1 37 287.431 8 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-N-ethyl-3-(methylaminomethyl)imidazo[1,2-a]pyridin-2-amine N-(cyclopropylmethyl)-N-ethyl-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 9.57 -44.52 2 4 1 37 259.377 6 ↓
Hi High (pH 8-9.5) 2.57 8.62 -8.58 1 4 0 33 258.369 6 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-N-ethyl-3-(ethylaminomethyl)imidazo[1,2-a]pyridin-2-amine N-(cyclopropylmethyl)-N-ethyl-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 10.42 -45.94 2 4 1 37 273.404 7 ↓
Hi High (pH 8-9.5) 2.95 9.05 -7.8 1 4 0 33 272.396 7 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-N-ethyl-3-[(isopropylamino)methyl]imidazo[1,2-a]pyridin-2-amine N-(cyclopropylmethyl)-N-ethyl-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 10.95 -40.51 2 4 1 37 287.431 7 ↓
Hi High (pH 8-9.5) 3.24 10.22 -8.09 1 4 0 33 286.423 7 ↓

Analogs

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Popular Name: 3-(aminomethyl)-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-(aminomethyl)-N-(cyclopropylme…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 7.63 -50.36 3 4 1 48 245.35 5 ↓
Hi High (pH 8-9.5) 2.20 7.43 -9.28 2 4 0 47 244.342 5 ↓

Analogs

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Popular Name: (E)-3-[2-[cyclopropylmethyl(ethyl)amino]imidazo[1,2-a]pyridin-3-yl]prop-2-enoic (E)-3-[2-[cyclopropylmethyl(ethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 9.68 -49.85 1 5 0 62 285.347 6 ↓
Mid Mid (pH 6-8) 2.80 10.45 -54.97 1 5 0 62 285.347 6 ↓
Mid Mid (pH 6-8) 2.80 9.93 -57.5 0 5 -1 61 284.339 6 ↓

Analogs

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Popular Name: 3-[(2R)-2-aminopropyl]-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-[(2R)-2-aminopropyl]-N-(cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 8.91 -48.21 3 4 1 48 273.404 6 ↓
Lo Low (pH 4.5-6) 2.40 9.1 -101.3 4 4 2 49 274.412 6 ↓

Analogs

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Popular Name: 3-[(2S)-2-aminopropyl]-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-[(2S)-2-aminopropyl]-N-(cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 9.06 -49.94 3 4 1 48 273.404 6 ↓
Lo Low (pH 4.5-6) 2.40 9.25 -106.87 4 4 2 49 274.412 6 ↓

Analogs

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Popular Name: 3-[(2S)-2-aminobutyl]-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-[(2S)-2-aminobutyl]-N-(cyclopr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 9.74 -47.07 3 4 1 48 287.431 7 ↓
Lo Low (pH 4.5-6) 2.93 9.97 -106.51 4 4 2 49 288.439 7 ↓

Analogs

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Popular Name: 3-[(2R)-2-aminobutyl]-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-[(2R)-2-aminobutyl]-N-(cyclopr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 9.82 -49.13 3 4 1 48 287.431 7 ↓
Lo Low (pH 4.5-6) 2.93 9.81 -101.82 4 4 2 49 288.439 7 ↓

Analogs

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Popular Name: 3-(2-aminoethyl)-N-(cyclopropylmethyl)-N-ethyl-imidazo[1,2-a]pyridin-2-amine 3-(2-aminoethyl)-N-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 8.16 -57.31 3 4 1 48 259.377 6 ↓
Lo Low (pH 4.5-6) 2.00 8.34 -109.3 4 4 2 49 260.385 6 ↓

Analogs

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Popular Name: N-[[(1S,2R)-2-methylcyclopropyl]methyl]-3-nitro-imidazo[1,2-a]pyridin-2-amine N-[[(1S,2R)-2-methylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 9.52 -9.81 1 6 0 75 246.27 4 ↓

Analogs

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Popular Name: N-[[(1S,2S)-2-methylcyclopropyl]methyl]-3-nitro-imidazo[1,2-a]pyridin-2-amine N-[[(1S,2S)-2-methylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 9.59 -9.78 1 6 0 75 246.27 4 ↓

Analogs

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Popular Name: N-[[(1R,2R)-2-methylcyclopropyl]methyl]-3-nitro-imidazo[1,2-a]pyridin-2-amine N-[[(1R,2R)-2-methylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 9.59 -9.8 1 6 0 75 246.27 4 ↓

Analogs

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Popular Name: N-[[(1R,2S)-2-methylcyclopropyl]methyl]-3-nitro-imidazo[1,2-a]pyridin-2-amine N-[[(1R,2S)-2-methylcyclopropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 9.52 -9.81 1 6 0 75 246.27 4 ↓

Analogs

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Popular Name: N-(cyclopropylmethyl)-N-methyl-3-nitro-imidazo[1,2-a]pyridin-2-amine N-(cyclopropylmethyl)-N-methyl-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 10.77 -10.65 0 6 0 66 246.27 4 ↓

Analogs

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Popular Name: 2-(cyclopropylmethylamino)imidazo[1,2-a]pyridine-3-carboxylic 2-(cyclopropylmethylamino)imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 7.79 -67.75 3 5 1 75 232.263 4 ↓
Mid Mid (pH 6-8) 1.96 6.74 -47.67 2 5 0 71 231.255 4 ↓

Parameters Provided:

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 325299 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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