ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

6051512

Analogs

3461397
3461401

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2,6-dichlorophenyl)methyl]-5-methyl-5-(4-tert-butylphenyl)-imidazolidine-2,4-dione 3-[(2,6-dichlorophenyl)methyl]-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.57	0.54	-7.24	1	4	0	49	405.325	4	↓ MOL2 SDF SMILES Flexibase

6051514

Analogs

3461397
3461401

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2,6-dichlorophenyl)methyl]-5-methyl-5-(4-tert-butylphenyl)-imidazolidine-2,4-dione 3-[(2,6-dichlorophenyl)methyl]-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.57	0.54	-7.24	1	4	0	49	405.325	4	↓ MOL2 SDF SMILES Flexibase

6051566

Analogs

3349875

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(5-acetyl-2-methoxy-phenyl)methyl]-5-(4-chlorophenyl)-5-ethyl-imidazolidine-2,4-dione 3-[(5-acetyl-2-methoxy-phenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	1.44	-13.66	1	6	0	75	400.862	6	↓ MOL2 SDF SMILES Flexibase

44018351

Analogs

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Popular Name: (5S)-3-benzyl-5-nonyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-benzyl-5-nonyl-5-phenyl-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.70	14.14	-7.45	1	4	0	49	392.543	11	↓ MOL2 SDF SMILES Flexibase

44018353

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-benzyl-5-nonyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-benzyl-5-nonyl-5-phenyl-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.70	14.04	-7.27	1	4	0	49	392.543	11	↓ MOL2 SDF SMILES Flexibase

10497272

Analogs

10497277

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2-bromo-4-fluoro-phenyl)methyl]-5-(2,5-difluorophenyl)-5-methyl-imidazolidine-2,4-dione 3-[(2-bromo-4-fluoro-phenyl)meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	1.9	-8.33	1	4	0	49	413.193	3	↓ MOL2 SDF SMILES Flexibase

10497277

Analogs

10497272

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(2-bromo-4-fluoro-phenyl)methyl]-5-(2,5-difluorophenyl)-5-methyl-imidazolidine-2,4-dione 3-[(2-bromo-4-fluoro-phenyl)meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	1.86	-8.42	1	4	0	49	413.193	3	↓ MOL2 SDF SMILES Flexibase

11538364

Analogs

11538365
5791457

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[4-(2,5-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]methyl]-3-fluoro-benzonitrile 4-[[4-(2,5-difluorophenyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.70	3.2	-11.16	1	5	0	73	359.307	3	↓ MOL2 SDF SMILES Flexibase

11538365

Analogs

5791457
11538364

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[4-(2,5-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]methyl]-3-fluoro-benzonitrile 4-[[4-(2,5-difluorophenyl)-4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.70	3.18	-10.85	1	5	0	73	359.307	3	↓ MOL2 SDF SMILES Flexibase

22357324

Analogs

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Popular Name: (5S)-5-(2-chlorophenyl)-5-methyl-3-[(2,3,4,5,6-pentafluorophenyl)methyl]imidazolidine-2,4-dione (5S)-5-(2-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	8.38	-8.75	1	4	0	49	404.722	3	↓ MOL2 SDF SMILES Flexibase

22357326

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(2-chlorophenyl)-5-methyl-3-[(2,3,4,5,6-pentafluorophenyl)methyl]imidazolidine-2,4-dione (5R)-5-(2-chlorophenyl)-5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	8.36	-8.91	1	4	0	49	404.722	3	↓ MOL2 SDF SMILES Flexibase

36640957

Analogs

36640959

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-[(2-chloro-4-fluoro-phenyl)methyl]-5-(4-methoxyphenyl)-5-methyl-imidazolidine-2,4-dione (5S)-3-[(2-chloro-4-fluoro-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.43	7.31	-8.14	1	5	0	59	362.788	4	↓ MOL2 SDF SMILES Flexibase

36640959

Analogs

36640957

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-[(2-chloro-4-fluoro-phenyl)methyl]-5-(4-methoxyphenyl)-5-methyl-imidazolidine-2,4-dione (5R)-3-[(2-chloro-4-fluoro-pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.43	7.31	-8.45	1	5	0	59	362.788	4	↓ MOL2 SDF SMILES Flexibase

22704113

Analogs

4303187
4303203
4468466

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(4-chlorophenyl)-3-[(3,4-dichlorophenyl)methyl]-5-methyl-imidazolidine-2,4-dione (5S)-5-(4-chlorophenyl)-3-[(3,4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	9.04	-9.37	1	4	0	49	383.662	3	↓ MOL2 SDF SMILES Flexibase

22704117

Analogs

4303187
4303203
4468466

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(4-chlorophenyl)-3-[(3,4-dichlorophenyl)methyl]-5-methyl-imidazolidine-2,4-dione (5R)-5-(4-chlorophenyl)-3-[(3,4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	9.02	-8.98	1	4	0	49	383.662	3	↓ MOL2 SDF SMILES Flexibase

22705423

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-[(3,4-dichlorophenyl)methyl]-5-(4-methoxyphenyl)-5-methyl-imidazolidine-2,4-dione (5R)-3-[(3,4-dichlorophenyl)meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.94	7.82	-9.79	1	5	0	59	379.243	4	↓ MOL2 SDF SMILES Flexibase

22705426

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-[(3,4-dichlorophenyl)methyl]-5-(4-methoxyphenyl)-5-methyl-imidazolidine-2,4-dione (5S)-3-[(3,4-dichlorophenyl)meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.94	7.84	-10	1	5	0	59	379.243	4	↓ MOL2 SDF SMILES Flexibase

22705449

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(4-chlorophenyl)-5-ethyl-3-[(4-fluorophenyl)methyl]imidazolidine-2,4-dione (5S)-5-(4-chlorophenyl)-5-ethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	9.4	-8.57	1	4	0	49	346.789	4	↓ MOL2 SDF SMILES Flexibase

22705452

Analogs

21741127

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(4-chlorophenyl)-5-ethyl-3-[(4-fluorophenyl)methyl]imidazolidine-2,4-dione (5R)-5-(4-chlorophenyl)-5-ethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	9.17	-8.78	1	4	0	49	346.789	4	↓ MOL2 SDF SMILES Flexibase

36875639

Analogs

36875640
3460066

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-benzyl-5-methyl-5-(4-nitrophenyl)imidazolidine-2,4-dione (5S)-3-benzyl-5-methyl-5-(4-nitr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	8.33	-11.17	1	7	0	95	325.324	4	↓ MOL2 SDF SMILES Flexibase

36875640

Analogs

36875639
3460066

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-benzyl-5-methyl-5-(4-nitrophenyl)imidazolidine-2,4-dione (5R)-3-benzyl-5-methyl-5-(4-nitr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	8.33	-11.01	1	7	0	95	325.324	4	↓ MOL2 SDF SMILES Flexibase

36875716

Analogs

36875717

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4S)-1-[(3,4-dichlorophenyl)methyl]-4-methyl-2,5-dioxo-imidazolidin-4-yl]benzonitrile 4-[(4S)-1-[(3,4-dichlorophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.64	8.98	-11.27	1	5	0	73	374.227	3	↓ MOL2 SDF SMILES Flexibase

36875717

Analogs

36875716

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4R)-1-[(3,4-dichlorophenyl)methyl]-4-methyl-2,5-dioxo-imidazolidin-4-yl]benzonitrile 4-[(4R)-1-[(3,4-dichlorophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.64	8.99	-10.98	1	5	0	73	374.227	3	↓ MOL2 SDF SMILES Flexibase

36876064

Analogs

36876065
3462111
4477272

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Popular Name: (5S)-3-benzyl-5-(4-chlorophenyl)-5-ethyl-imidazolidine-2,4-dione (5S)-3-benzyl-5-(4-chlorophenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.78	9.22	-7.49	1	4	0	49	328.799	4	↓ MOL2 SDF SMILES Flexibase

36876065

Analogs

36876064
3462111
4477272

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-benzyl-5-(4-chlorophenyl)-5-ethyl-imidazolidine-2,4-dione (5R)-3-benzyl-5-(4-chlorophenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.78	9.13	-7.49	1	4	0	49	328.799	4	↓ MOL2 SDF SMILES Flexibase

58321535

Analogs

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Popular Name: (5S)-3-[(4-bromo-2-fluoro-phenyl)methyl]-5-(4-fluorophenyl)-5-methyl-imidazolidine-2,4-dione (5S)-3-[(4-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	8.33	-9.04	1	4	0	49	395.203	3	↓ MOL2 SDF SMILES Flexibase

58321538

Analogs

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Popular Name: (5R)-3-[(4-bromo-2-fluoro-phenyl)methyl]-5-(4-fluorophenyl)-5-methyl-imidazolidine-2,4-dione (5R)-3-[(4-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	8.34	-8.75	1	4	0	49	395.203	3	↓ MOL2 SDF SMILES Flexibase

59008374

Analogs

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Popular Name: (5S)-3-[(5-bromo-2-fluoro-phenyl)methyl]-5-methyl-5-phenyl-imidazolidine-2,4-dione (5S)-3-[(5-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	8.25	-8.1	1	4	0	49	377.213	3	↓ MOL2 SDF SMILES Flexibase

59008375

Analogs

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Popular Name: (5R)-3-[(5-bromo-2-fluoro-phenyl)methyl]-5-methyl-5-phenyl-imidazolidine-2,4-dione (5R)-3-[(5-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	8.25	-7.96	1	4	0	49	377.213	3	↓ MOL2 SDF SMILES Flexibase

59008500

Analogs

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Popular Name: (5S)-3-[(5-bromo-2-fluoro-phenyl)methyl]-5-methyl-5-(4-nitrophenyl)imidazolidine-2,4-dione (5S)-3-[(5-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.46	8.96	-11.66	1	7	0	95	422.21	4	↓ MOL2 SDF SMILES Flexibase

59008502

Analogs

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Popular Name: (5R)-3-[(5-bromo-2-fluoro-phenyl)methyl]-5-methyl-5-(4-nitrophenyl)imidazolidine-2,4-dione (5R)-3-[(5-bromo-2-fluoro-phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.46	8.96	-11.64	1	7	0	95	422.21	4	↓ MOL2 SDF SMILES Flexibase

59009752

Analogs

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Popular Name: (5S)-5-butyl-3-[(2-methyl-3-nitro-phenyl)methyl]-5-phenyl-imidazolidine-2,4-dione (5S)-5-butyl-3-[(2-methyl-3-nitr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.48	11.74	-10.57	1	7	0	95	381.432	7	↓ MOL2 SDF SMILES Flexibase

59009754

Analogs

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Popular Name: (5R)-5-butyl-3-[(2-methyl-3-nitro-phenyl)methyl]-5-phenyl-imidazolidine-2,4-dione (5R)-5-butyl-3-[(2-methyl-3-nitr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.48	11.29	-10.58	1	7	0	95	381.432	7	↓ MOL2 SDF SMILES Flexibase

59010303

Analogs

46875413
46875415

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Popular Name: (5R)-5-(4-isopropylphenyl)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]imidazolidine-2,4-dione (5R)-5-(4-isopropylphenyl)-5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.43	10.62	-10.4	1	7	0	95	381.432	5	↓ MOL2 SDF SMILES Flexibase

59010305

Analogs

46875413
46875415

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(4-isopropylphenyl)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]imidazolidine-2,4-dione (5S)-5-(4-isopropylphenyl)-5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.43	10.64	-9.89	1	7	0	95	381.432	5	↓ MOL2 SDF SMILES Flexibase

59010584

Analogs

46875413
46875415

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]-5-(4-propylphenyl)imidazolidine-2,4-dione (5R)-5-methyl-3-[(2-methyl-3-nit…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.22	11.37	-10.89	1	7	0	95	381.432	6	↓ MOL2 SDF SMILES Flexibase

59010586

Analogs

46875413
46875415

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]-5-(4-propylphenyl)imidazolidine-2,4-dione (5S)-5-methyl-3-[(2-methyl-3-nit…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.22	11.36	-10.29	1	7	0	95	381.432	6	↓ MOL2 SDF SMILES Flexibase

59011191

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(3,4-dichlorophenyl)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]imidazolidine-2,4-dione (5R)-5-(3,4-dichlorophenyl)-5-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.20	9.66	-10.55	1	7	0	95	408.241	4	↓ MOL2 SDF SMILES Flexibase

59011194

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(3,4-dichlorophenyl)-5-methyl-3-[(2-methyl-3-nitro-phenyl)methyl]imidazolidine-2,4-dione (5S)-5-(3,4-dichlorophenyl)-5-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.20	9.68	-10.25	1	7	0	95	408.241	4	↓ MOL2 SDF SMILES Flexibase

14013677

Analogs

9861517
9861518

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Popular Name: 4-[[(4S)-4-ethyl-2,5-dioxo-4-(p-tolyl)imidazolidin-1-yl]methyl]benzamide 4-[[(4S)-4-ethyl-2,5-dioxo-4-(p-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	6.13	-12.68	3	6	0	93	351.406	5	↓ MOL2 SDF SMILES Flexibase

14013680

Analogs

9861517
9861518

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[(4R)-4-ethyl-2,5-dioxo-4-(p-tolyl)imidazolidin-1-yl]methyl]benzamide 4-[[(4R)-4-ethyl-2,5-dioxo-4-(p-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	6.17	-12.58	3	6	0	93	351.406	5	↓ MOL2 SDF SMILES Flexibase

14242121

Analogs

14242122
16710185
16732964
16732967
16733042

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Popular Name: 4-[(4S)-1-[(5-chloro-2-methoxy-phenyl)methyl]-4-methyl-2,5-dioxo-imidazolidin-4-yl]benzonitrile 4-[(4S)-1-[(5-chloro-2-methoxy-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	9.03	-11.35	1	6	0	82	369.808	4	↓ MOL2 SDF SMILES Flexibase

14242122

Analogs

16710185
16732964
16732967
16733042
16733044

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4R)-1-[(5-chloro-2-methoxy-phenyl)methyl]-4-methyl-2,5-dioxo-imidazolidin-4-yl]benzonitrile 4-[(4R)-1-[(5-chloro-2-methoxy-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	9.09	-11.01	1	6	0	82	369.808	4	↓ MOL2 SDF SMILES Flexibase

3594239

Analogs

3517198
3517199

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Popular Name: 2-[[(4S)-4-(2-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]methyl]benzonitrile 2-[[(4S)-4-(2-bromophenyl)-2,5-d…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.07	0.33	-11.29	1	5	0	73	384.233	3	↓ MOL2 SDF SMILES Flexibase

14557916

Analogs

14557919

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-3-[[2-(difluoromethoxy)phenyl]methyl]-5-ethyl-5-(4-fluorophenyl)imidazolidine-2,4-dione (5S)-3-[[2-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.83	9.66	-9.43	1	5	0	59	378.35	6	↓ MOL2 SDF SMILES Flexibase

14557919

Analogs

14557916

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-3-[[2-(difluoromethoxy)phenyl]methyl]-5-ethyl-5-(4-fluorophenyl)imidazolidine-2,4-dione (5R)-3-[[2-(difluoromethoxy)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.83	9.57	-9.39	1	5	0	59	378.35	6	↓ MOL2 SDF SMILES Flexibase

68951899

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(4-isopropylphenyl)-5-methyl-3-[(2-nitrophenyl)methyl]imidazolidine-2,4-dione (5R)-5-(4-isopropylphenyl)-5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.03	10.49	-12.72	1	7	0	95	367.405	5	↓ MOL2 SDF SMILES Flexibase

68951902

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(4-isopropylphenyl)-5-methyl-3-[(2-nitrophenyl)methyl]imidazolidine-2,4-dione (5S)-5-(4-isopropylphenyl)-5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.03	10.48	-11.51	1	7	0	95	367.405	5	↓ MOL2 SDF SMILES Flexibase

68951921

Analogs

7007810
7007811
8643653
8643655

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-5-(4-isopropylphenyl)-3-[(3-methoxyphenyl)methyl]-5-methyl-imidazolidine-2,4-dione (5R)-5-(4-isopropylphenyl)-3-[(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.15	8.87	-9.03	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

68951924

Analogs

7007810
7007811
8643653
8643655

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-5-(4-isopropylphenyl)-3-[(3-methoxyphenyl)methyl]-5-methyl-imidazolidine-2,4-dione (5S)-5-(4-isopropylphenyl)-3-[(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.15	8.85	-9.33	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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SQL Query Was

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