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Analogs

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Popular Name: N-[4-[[2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetyl]amino]-2-methoxy-phenyl]-3-methyl-butanamide N-[4-[[2-[(4R)-2,5-dioxoimidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 0.2 -17.55 4 9 0 126 362.386 7 ↓
Hi High (pH 8-9.5) 2.22 -2.46 -48.44 3 9 -1 132 361.378 7 ↓

Analogs

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Popular Name: N-[4-[[2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetyl]amino]-2-methoxy-phenyl]-3-methyl-butanamide N-[4-[[2-[(4S)-2,5-dioxoimidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 0.2 -18.27 4 9 0 126 362.386 7 ↓
Hi High (pH 8-9.5) 2.22 -2.46 -49.7 3 9 -1 132 361.378 7 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxoimidazolidin-4-yl]-N-(3-fluoro-4-methoxy-phenyl)acetamide 2-[(4R)-2,5-dioxoimidazolidin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 -0.92 -14.08 3 7 0 97 281.243 4 ↓
Hi High (pH 8-9.5) 1.55 -3.57 -42.87 2 7 -1 103 280.235 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxoimidazolidin-4-yl]-N-(3-fluoro-4-methoxy-phenyl)acetamide 2-[(4S)-2,5-dioxoimidazolidin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 -0.91 -16.69 3 7 0 97 281.243 4 ↓
Hi High (pH 8-9.5) 1.55 -3.56 -46.92 2 7 -1 103 280.235 4 ↓

Analogs

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Popular Name: N-(4-chloro-3-fluoro-phenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetamide N-(4-chloro-3-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 0.28 -12.49 3 6 0 87 285.662 3 ↓
Hi High (pH 8-9.5) 2.17 -2.37 -40.55 2 6 -1 94 284.654 3 ↓

Analogs

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Popular Name: N-(4-chloro-3-fluoro-phenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetamide N-(4-chloro-3-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 0.29 -14.65 3 6 0 87 285.662 3 ↓
Hi High (pH 8-9.5) 2.17 -2.36 -43.67 2 6 -1 94 284.654 3 ↓

Analogs

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Popular Name: N-(5-bromo-2-methyl-phenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetamide N-(5-bromo-2-methyl-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 1.24 -12.75 3 6 0 87 326.15 3 ↓
Hi High (pH 8-9.5) 2.59 -1.42 -43.59 2 6 -1 94 325.142 3 ↓

Analogs

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Popular Name: N-(5-bromo-2-methyl-phenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetamide N-(5-bromo-2-methyl-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 1.24 -12.62 3 6 0 87 326.15 3 ↓
Hi High (pH 8-9.5) 2.59 -1.41 -43.24 2 6 -1 94 325.142 3 ↓

Analogs

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Popular Name: N-(3-chloro-2-methoxy-phenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetamide N-(3-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 -0.2 -11.08 3 7 0 97 297.698 4 ↓
Hi High (pH 8-9.5) 2.04 -2.85 -40.84 2 7 -1 103 296.69 4 ↓

Analogs

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Popular Name: N-(3-chloro-2-methoxy-phenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetamide N-(3-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 -0.2 -11.11 3 7 0 97 297.698 4 ↓
Hi High (pH 8-9.5) 2.04 -2.86 -40.77 2 7 -1 103 296.69 4 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxoimidazolidin-4-yl]-N-(4-isopropoxyphenyl)acetamide 2-[(4R)-2,5-dioxoimidazolidin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.01 0.62 -13.04 3 7 0 97 291.307 5 ↓
Hi High (pH 8-9.5) 2.19 -2.03 -43.72 2 7 -1 103 290.299 5 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxoimidazolidin-4-yl]-N-(4-isopropoxyphenyl)acetamide 2-[(4S)-2,5-dioxoimidazolidin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.01 0.56 -12.92 3 7 0 97 291.307 5 ↓
Hi High (pH 8-9.5) 2.19 -2.09 -43.63 2 7 -1 103 290.299 5 ↓

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]-N-methyl-acetamide N-(2,5-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 3.24 -11.65 2 6 0 79 275.308 3 ↓
Hi High (pH 8-9.5) 1.80 0.59 -43.38 1 6 -1 85 274.3 3 ↓

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]-N-methyl-acetamide N-(2,5-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 3.24 -11.65 2 6 0 79 275.308 3 ↓
Hi High (pH 8-9.5) 1.80 0.59 -43.24 1 6 -1 85 274.3 3 ↓

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]-N-methyl-acetamide N-(3,5-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 2.78 -11.66 2 6 0 79 275.308 3 ↓
Hi High (pH 8-9.5) 1.80 0.14 -43.52 1 6 -1 85 274.3 3 ↓

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]-N-methyl-acetamide N-(3,5-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 2.78 -11.64 2 6 0 79 275.308 3 ↓
Hi High (pH 8-9.5) 1.80 0.13 -43.39 1 6 -1 85 274.3 3 ↓

Analogs

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Popular Name: N-(2,3-difluorophenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetamide N-(2,3-difluorophenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 -0.11 -11.79 3 6 0 87 269.207 3 ↓
Hi High (pH 8-9.5) 1.63 -2.76 -41.22 2 6 -1 94 268.199 3 ↓

Analogs

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Popular Name: N-(2,3-difluorophenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetamide N-(2,3-difluorophenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 -0.11 -11.85 3 6 0 87 269.207 3 ↓
Hi High (pH 8-9.5) 1.63 -2.76 -41.62 2 6 -1 94 268.199 3 ↓

Analogs

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Popular Name: N-(5-cyano-2-methyl-phenyl)-2-[(4R)-2,5-dioxoimidazolidin-4-yl]acetamide N-(5-cyano-2-methyl-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.35 1 -16.16 3 7 0 111 272.264 3 ↓
Hi High (pH 8-9.5) 1.53 -1.66 -46.81 2 7 -1 117 271.256 3 ↓

Analogs

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Popular Name: N-(5-cyano-2-methyl-phenyl)-2-[(4S)-2,5-dioxoimidazolidin-4-yl]acetamide N-(5-cyano-2-methyl-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.35 1 -15.94 3 7 0 111 272.264 3 ↓
Hi High (pH 8-9.5) 1.53 -1.66 -46.24 2 7 -1 117 271.256 3 ↓

Parameters Provided:

ring.id = 327403
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 327403 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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