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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[[4-(2-aminoethyl)phenyl]methyl]piperidine-2,6-dione 1-[[4-(2-aminoethyl)phenyl]methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.28 5.06 -51.64 3 4 1 65 247.318 4 ↓

Analogs

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Popular Name: (3S)-3-amino-1-(m-tolylmethyl)piperidine-2,6-dione (3S)-3-amino-1-(m-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.07 4.2 -54.03 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.07 3.88 -7.63 2 4 0 63 232.283 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-(m-tolylmethyl)piperidine-2,6-dione (3R)-3-amino-1-(m-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.07 4.2 -53.91 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.07 3.88 -9.42 2 4 0 63 232.283 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-(p-tolylmethyl)piperidine-2,6-dione (3S)-3-amino-1-(p-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.10 4.2 -53.98 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.10 3.88 -7.59 2 4 0 63 232.283 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-(p-tolylmethyl)piperidine-2,6-dione (3R)-3-amino-1-(p-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.10 4.2 -53.82 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.10 3.88 -9.38 2 4 0 63 232.283 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-(o-tolylmethyl)piperidine-2,6-dione (3S)-3-amino-1-(o-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.05 4.55 -56.53 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.05 4.22 -9.48 2 4 0 63 232.283 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-(o-tolylmethyl)piperidine-2,6-dione (3R)-3-amino-1-(o-tolylmethyl)pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.05 4.54 -56.73 3 4 1 65 233.291 2 ↓
Mid Mid (pH 6-8) 0.05 4.22 -11.22 2 4 0 63 232.283 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(4-ethylphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(4-ethylphenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 4.96 -53.78 3 4 1 65 247.318 3 ↓
Mid Mid (pH 6-8) 0.56 4.64 -7.31 2 4 0 63 246.31 3 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(4-ethylphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(4-ethylphenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 4.97 -53.66 3 4 1 65 247.318 3 ↓
Mid Mid (pH 6-8) 0.56 4.64 -9.15 2 4 0 63 246.31 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(2,5-dimethylphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(2,5-dimethylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.47 5.23 -57.27 3 4 1 65 247.318 2 ↓
Mid Mid (pH 6-8) 0.47 4.89 -9.68 2 4 0 63 246.31 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(2,5-dimethylphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(2,5-dimethylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.47 5.24 -57.95 3 4 1 65 247.318 2 ↓
Mid Mid (pH 6-8) 0.47 4.91 -11.42 2 4 0 63 246.31 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(3-methoxyphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(3-methoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.32 2.81 -54.36 3 5 1 74 249.29 3 ↓
Mid Mid (pH 6-8) -0.32 2.49 -9.41 2 5 0 73 248.282 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-[(3-methoxyphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(3-methoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.32 2.82 -53.8 3 5 1 74 249.29 3 ↓
Mid Mid (pH 6-8) -0.32 2.5 -11.42 2 5 0 73 248.282 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(3-chlorophenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(3-chlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.30 4.03 -53.37 3 4 1 65 253.709 2 ↓
Mid Mid (pH 6-8) 0.30 3.71 -7.19 2 4 0 63 252.701 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-[(3-chlorophenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(3-chlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.30 4.04 -52.89 3 4 1 65 253.709 2 ↓
Mid Mid (pH 6-8) 0.30 3.72 -9.09 2 4 0 63 252.701 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(4-isopropylphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(4-isopropylphen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.16 5.45 -53.64 3 4 1 65 261.345 3 ↓
Mid Mid (pH 6-8) 1.16 5.13 -7.21 2 4 0 63 260.337 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-[(4-isopropylphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(4-isopropylphen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.16 5.45 -53.53 3 4 1 65 261.345 3 ↓
Mid Mid (pH 6-8) 1.16 5.13 -9 2 4 0 63 260.337 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(2,4,6-trimethylphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(2,4,6-trimethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 5.21 -53.46 3 4 1 65 261.345 2 ↓
Mid Mid (pH 6-8) 0.85 4.89 -6.12 2 4 0 63 260.337 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(2,4,6-trimethylphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(2,4,6-trimethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 5.27 -52.86 3 4 1 65 261.345 2 ↓
Mid Mid (pH 6-8) 0.85 4.94 -7.67 2 4 0 63 260.337 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(2-methoxy-5-methyl-phenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(2-methoxy-5-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.08 4.89 -53.18 3 5 1 74 263.317 3 ↓
Mid Mid (pH 6-8) 0.08 4.56 -8.47 2 5 0 73 262.309 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-3-amino-1-[(2-methoxy-5-methyl-phenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(2-methoxy-5-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.08 4.89 -52.94 3 5 1 74 263.317 3 ↓
Mid Mid (pH 6-8) 0.08 4.58 -10.27 2 5 0 73 262.309 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(3-fluoro-4-methoxy-phenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(3-fluoro-4-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.20 2.89 -56.12 3 5 1 74 267.28 3 ↓
Mid Mid (pH 6-8) -0.20 2.58 -9.81 2 5 0 73 266.272 3 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(3-fluoro-4-methoxy-phenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(3-fluoro-4-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.20 2.89 -55.39 3 5 1 74 267.28 3 ↓
Mid Mid (pH 6-8) -0.20 2.58 -11.73 2 5 0 73 266.272 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(2-chloro-6-fluoro-phenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(2-chloro-6-fluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.40 3.98 -54.34 3 4 1 65 271.699 2 ↓
Mid Mid (pH 6-8) 0.40 3.66 -8.77 2 4 0 63 270.691 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(2-chloro-6-fluoro-phenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(2-chloro-6-fluo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.40 3.98 -54.31 3 4 1 65 271.699 2 ↓
Mid Mid (pH 6-8) 0.40 3.67 -10.27 2 4 0 63 270.691 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(4-tert-butylphenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(4-tert-butylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 5.84 -53.63 3 4 1 65 275.372 3 ↓
Mid Mid (pH 6-8) 1.36 5.52 -7.13 2 4 0 63 274.364 3 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(4-tert-butylphenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(4-tert-butylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 5.84 -53.57 3 4 1 65 275.372 3 ↓
Mid Mid (pH 6-8) 1.36 5.52 -8.97 2 4 0 63 274.364 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(5-chloro-2-methoxy-phenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(5-chloro-2-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.31 4.73 -52.83 3 5 1 74 283.735 3 ↓
Mid Mid (pH 6-8) 0.31 4.41 -7.93 2 5 0 73 282.727 3 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(5-chloro-2-methoxy-phenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(5-chloro-2-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.31 4.73 -52.44 3 5 1 74 283.735 3 ↓
Mid Mid (pH 6-8) 0.31 4.41 -9.78 2 5 0 73 282.727 3 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(3,4-dichlorophenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(3,4-dichlorophe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 4.48 -54.34 3 4 1 65 288.154 2 ↓
Mid Mid (pH 6-8) 0.93 4.16 -6.67 2 4 0 63 287.146 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(3,4-dichlorophenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(3,4-dichlorophe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 4.49 -53.77 3 4 1 65 288.154 2 ↓
Mid Mid (pH 6-8) 0.93 4.17 -8.36 2 4 0 63 287.146 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(2,4-dichlorophenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(2,4-dichlorophe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 4.96 -58.76 3 4 1 65 288.154 2 ↓
Mid Mid (pH 6-8) 0.93 4.63 -8.59 2 4 0 63 287.146 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(2,4-dichlorophenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(2,4-dichlorophe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 4.96 -59.55 3 4 1 65 288.154 2 ↓
Mid Mid (pH 6-8) 0.93 4.63 -9.66 2 4 0 63 287.146 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(3-bromophenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(3-bromophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.43 4.15 -53.25 3 4 1 65 298.16 2 ↓
Mid Mid (pH 6-8) 0.43 3.83 -7.06 2 4 0 63 297.152 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(3-bromophenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(3-bromophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.43 4.15 -52.74 3 4 1 65 298.16 2 ↓
Mid Mid (pH 6-8) 0.43 3.83 -8.97 2 4 0 63 297.152 2 ↓

Analogs

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Popular Name: (3S)-3-amino-1-[(4-bromophenyl)methyl]piperidine-2,6-dione (3S)-3-amino-1-[(4-bromophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.46 4.14 -54.46 3 4 1 65 298.16 2 ↓
Mid Mid (pH 6-8) 0.46 3.82 -6.48 2 4 0 63 297.152 2 ↓

Analogs

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Popular Name: (3R)-3-amino-1-[(4-bromophenyl)methyl]piperidine-2,6-dione (3R)-3-amino-1-[(4-bromophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.46 4.15 -54.19 3 4 1 65 298.16 2 ↓
Mid Mid (pH 6-8) 0.46 3.83 -8.02 2 4 0 63 297.152 2 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 8.05 -9.83 0 5 0 64 289.331 4 ↓

Analogs

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Popular Name: 1-[(1S)-1-(4-bromophenyl)ethyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(1S)-1-(4-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 8.79 -8.11 0 3 0 37 324.218 2 ↓

Analogs

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Popular Name: 1-[(1R)-1-(4-bromophenyl)ethyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(1R)-1-(4-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 8.76 -8.07 0 3 0 37 324.218 2 ↓

Analogs

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Popular Name: (2R)-2-(4,4-dimethyl-2,6-dioxo-1-piperidyl)-2-phenyl-acetonitrile (2R)-2-(4,4-dimethyl-2,6-dioxo-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.91 7.79 -12.48 0 4 0 61 256.305 2 ↓

Analogs

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Popular Name: (2S)-2-(4,4-dimethyl-2,6-dioxo-1-piperidyl)-2-phenyl-acetonitrile (2S)-2-(4,4-dimethyl-2,6-dioxo-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.91 7.76 -12.46 0 4 0 61 256.305 2 ↓

Analogs

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Popular Name: 1-[(4-bromophenyl)methyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(4-bromophenyl)methyl]-4,4-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 8.03 -6.76 0 3 0 37 310.191 2 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(3-bromophenyl)methyl]-4,4-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 8.03 -7.53 0 3 0 37 310.191 2 ↓

Analogs

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Popular Name: 1-[(3-bromo-4-fluoro-phenyl)methyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(3-bromo-4-fluoro-phenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.85 8.07 -7.28 0 3 0 37 328.181 2 ↓

Analogs

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Popular Name: 1-[(2-bromophenyl)methyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(2-bromophenyl)methyl]-4,4-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 7.88 -7.29 0 3 0 37 310.191 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(4,4-dimethyl-2,6-dioxo-1-piperidyl)methyl]benzonitrile 3-[(4,4-dimethyl-2,6-dioxo-1-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 7.8 -9.84 0 4 0 61 256.305 2 ↓

Analogs

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Popular Name: 1-[(1S)-1-(3-bromophenyl)ethyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(1S)-1-(3-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 8.79 -8.52 0 3 0 37 324.218 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(1R)-1-(3-bromophenyl)ethyl]-4,4-dimethyl-piperidine-2,6-dione 1-[(1R)-1-(3-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 8.75 -8.3 0 3 0 37 324.218 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(4,4-dimethyl-2,6-dioxo-1-piperidyl)methyl]benzonitrile 4-[(4,4-dimethyl-2,6-dioxo-1-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 7.8 -8.68 0 4 0 61 256.305 2 ↓

Parameters Provided:

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filter.purchasability = annotated
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Structural Results Found: (before additional filtering)

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