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Analogs

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Popular Name: (4R)-4-phenyl-N-(2,4,6-trichlorophenyl)-4,5-dihydrothiazol-2-amine (4R)-4-phenyl-N-(2,4,6-trichloro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.56 10.43 -6.4 1 2 0 24 357.693 2 ↓

Analogs

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Popular Name: (4S)-4-phenyl-N-(2,4,6-trichlorophenyl)-4,5-dihydrothiazol-2-amine (4S)-4-phenyl-N-(2,4,6-trichloro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.56 10.43 -6.38 1 2 0 24 357.693 2 ↓

Analogs

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Popular Name: (4R)-N-(4-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(4-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.76 9.59 -6.26 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.76 10.02 -30.55 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4S)-N-(4-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(4-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.76 9.59 -6.12 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.76 10.02 -30.58 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4R)-N-(4-bromo-2,6-dichloro-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(4-bromo-2,6-dichloro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.70 10.54 -6.38 1 2 0 24 402.144 2 ↓

Analogs

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Popular Name: (4S)-N-(4-bromo-2,6-dichloro-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(4-bromo-2,6-dichloro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.70 10.55 -6.38 1 2 0 24 402.144 2 ↓

Analogs

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Popular Name: (4R)-N-(3-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.73 9.58 -6.9 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.73 10.02 -29.8 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4S)-N-(3-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.73 9.58 -6.82 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.73 10.01 -29.3 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4R)-4-phenyl-N-(2,4,6-tribromophenyl)-4,5-dihydrothiazol-2-amine (4R)-4-phenyl-N-(2,4,6-tribromop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.96 10.81 -6.28 1 2 0 24 491.046 2 ↓

Analogs

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Popular Name: (4S)-4-phenyl-N-(2,4,6-tribromophenyl)-4,5-dihydrothiazol-2-amine (4S)-4-phenyl-N-(2,4,6-tribromop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.96 10.82 -6.28 1 2 0 24 491.046 2 ↓

Analogs

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Popular Name: (4R)-N-(2-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.71 9.76 -7.48 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.71 10.03 -27.85 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4S)-N-(2-iodophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-iodophenyl)-4-phenyl-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.71 9.78 -7.46 1 2 0 24 380.254 2 ↓
Lo Low (pH 4.5-6) 4.71 9.93 -27.45 2 2 1 26 381.262 3 ↓

Analogs

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Popular Name: (4R)-N-(2,6-dibromo-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2,6-dibromo-4-methyl-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.60 10.88 -7.86 1 2 0 24 426.177 2 ↓

Analogs

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Popular Name: (4S)-N-(2,6-dibromo-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2,6-dibromo-4-methyl-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.60 10.9 -7.84 1 2 0 24 426.177 2 ↓

Analogs

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Popular Name: (4R)-N-(3-chloro-4-fluoro-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-chloro-4-fluoro-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.44 9.05 -6.89 1 2 0 24 306.793 2 ↓
Lo Low (pH 4.5-6) 4.44 9.47 -33.3 2 2 1 26 307.801 3 ↓

Analogs

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Popular Name: (4S)-N-(3-chloro-4-fluoro-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-chloro-4-fluoro-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.44 9.06 -6.76 1 2 0 24 306.793 2 ↓
Lo Low (pH 4.5-6) 4.44 9.47 -33.32 2 2 1 26 307.801 3 ↓

Analogs

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Popular Name: (4R)-N,4-diphenyl-4,5-dihydrothiazol-2-amine (4R)-N,4-diphenyl-4,5-dihydrothi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.67 8.49 -7.79 1 2 0 24 254.358 2 ↓
Mid Mid (pH 6-8) 3.67 8.92 -27.27 2 2 1 26 255.366 3 ↓

Analogs

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Popular Name: (4S)-N,4-diphenyl-4,5-dihydrothiazol-2-amine (4S)-N,4-diphenyl-4,5-dihydrothi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.67 8.49 -7.66 1 2 0 24 254.358 2 ↓
Mid Mid (pH 6-8) 3.67 8.92 -27.3 2 2 1 26 255.366 3 ↓

Analogs

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Popular Name: (4R)-N-(2,5-dichlorophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2,5-dichlorophenyl)-4-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.96 9.64 -7.17 1 2 0 24 323.248 2 ↓

Analogs

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Popular Name: (4S)-N-(2,5-dichlorophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2,5-dichlorophenyl)-4-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.96 9.65 -7.17 1 2 0 24 323.248 2 ↓

Analogs

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Popular Name: (4R)-N-(2-ethyl-6-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-ethyl-6-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.94 10.69 -7.06 1 2 0 24 296.439 3 ↓
Mid Mid (pH 6-8) 4.00 11.12 -27.13 2 2 1 26 297.447 4 ↓

Analogs

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Popular Name: (4S)-N-(2-ethyl-6-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-ethyl-6-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.94 10.7 -7.07 1 2 0 24 296.439 3 ↓
Mid Mid (pH 6-8) 4.00 11.12 -26.73 2 2 1 26 297.447 4 ↓

Analogs

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Popular Name: (4R)-N-(3-methylsulfanylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-methylsulfanylphenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 9.51 -9.08 1 2 0 24 300.452 3 ↓
Lo Low (pH 4.5-6) 4.08 9.94 -28.33 2 2 1 26 301.46 4 ↓

Analogs

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Popular Name: (4S)-N-(3-methylsulfanylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-methylsulfanylphenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 9.52 -8.99 1 2 0 24 300.452 3 ↓
Lo Low (pH 4.5-6) 4.08 9.94 -28.36 2 2 1 26 301.46 4 ↓

Analogs

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Popular Name: (4R)-N-(3-chloro-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-chloro-4-methyl-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.73 9.6 -7.45 1 2 0 24 302.83 2 ↓
Lo Low (pH 4.5-6) 4.73 10.03 -29.73 2 2 1 26 303.838 3 ↓

Analogs

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Popular Name: (4S)-N-(3-chloro-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-chloro-4-methyl-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.73 9.61 -7.24 1 2 0 24 302.83 2 ↓
Lo Low (pH 4.5-6) 4.73 10.02 -29.31 2 2 1 26 303.838 3 ↓

Analogs

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Popular Name: (4R)-N-(2-bromo-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-bromo-4-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.86 9.9 -7.96 1 2 0 24 347.281 2 ↓
Lo Low (pH 4.5-6) 4.86 10.14 -27.55 2 2 1 26 348.289 3 ↓

Analogs

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Popular Name: (4S)-N-(2-bromo-4-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-bromo-4-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.86 9.9 -7.98 1 2 0 24 347.281 2 ↓
Lo Low (pH 4.5-6) 4.86 10.23 -27.79 2 2 1 26 348.289 3 ↓

Analogs

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Popular Name: (4R)-N-(2-methoxyphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-methoxyphenyl)-4-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.68 7.9 -10.36 1 3 0 34 284.384 3 ↓
Mid Mid (pH 6-8) 3.68 8.19 -26.74 2 3 1 35 285.392 4 ↓

Analogs

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Popular Name: (4S)-N-(2-methoxyphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-methoxyphenyl)-4-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.68 7.89 -10.34 1 3 0 34 284.384 3 ↓
Mid Mid (pH 6-8) 3.68 8.19 -26.74 2 3 1 35 285.392 4 ↓

Analogs

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Popular Name: (4R)-N-(2,6-dichloro-3-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2,6-dichloro-3-methyl-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.34 10.53 -8.59 1 2 0 24 337.275 2 ↓

Analogs

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Popular Name: (4S)-N-(2,6-dichloro-3-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2,6-dichloro-3-methyl-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.34 10.55 -8.53 1 2 0 24 337.275 2 ↓

Analogs

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Popular Name: (4R)-N-(3-chloro-4-methoxy-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-chloro-4-methoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.34 8.34 -8.72 1 3 0 34 318.829 3 ↓
Mid Mid (pH 6-8) 4.34 8.78 -32.32 2 3 1 35 319.837 4 ↓

Analogs

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Popular Name: (4S)-N-(3-chloro-4-methoxy-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-chloro-4-methoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.34 8.35 -8.55 1 3 0 34 318.829 3 ↓
Mid Mid (pH 6-8) 4.34 8.76 -31.81 2 3 1 35 319.837 4 ↓

Analogs

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Popular Name: (4R)-N-(2-ethoxyphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-ethoxyphenyl)-4-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 8.84 -10.23 1 3 0 34 298.411 4 ↓
Mid Mid (pH 6-8) 4.06 9.12 -26.43 2 3 1 35 299.419 5 ↓

Analogs

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Popular Name: (4S)-N-(2-ethoxyphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-ethoxyphenyl)-4-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 8.82 -10.22 1 3 0 34 298.411 4 ↓
Mid Mid (pH 6-8) 4.06 9.12 -26.36 2 3 1 35 299.419 5 ↓

Analogs

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Popular Name: (4R)-N-(3-chloro-2-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(3-chloro-2-methyl-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.70 9.83 -7.01 1 2 0 24 302.83 2 ↓
Lo Low (pH 4.5-6) 4.70 9.97 -30.26 2 2 1 26 303.838 3 ↓

Analogs

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Popular Name: (4S)-N-(3-chloro-2-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(3-chloro-2-methyl-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.70 9.83 -6.93 1 2 0 24 302.83 2 ↓
Lo Low (pH 4.5-6) 4.70 9.97 -30.36 2 2 1 26 303.838 3 ↓

Analogs

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Popular Name: (4R)-N-(2,4-dichlorophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2,4-dichlorophenyl)-4-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.96 9.63 -6.82 1 2 0 24 323.248 2 ↓

Analogs

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Popular Name: (4S)-N-(2,4-dichlorophenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2,4-dichlorophenyl)-4-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.96 9.65 -6.86 1 2 0 24 323.248 2 ↓

Analogs

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Popular Name: (4R)-N-(4-bromo-2-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(4-bromo-2-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.86 10.02 -6.39 1 2 0 24 347.281 2 ↓
Lo Low (pH 4.5-6) 4.86 10.23 -30.86 2 2 1 26 348.289 3 ↓

Analogs

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Popular Name: (4S)-N-(4-bromo-2-methyl-phenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(4-bromo-2-methyl-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.86 10.01 -6.32 1 2 0 24 347.281 2 ↓
Lo Low (pH 4.5-6) 4.86 10.24 -30.87 2 2 1 26 348.289 3 ↓

Analogs

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Popular Name: (4R)-4-phenyl-N-(2,4,5-trichlorophenyl)-4,5-dihydrothiazol-2-amine (4R)-4-phenyl-N-(2,4,5-trichloro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.56 10.08 -6.18 1 2 0 24 357.693 2 ↓

Analogs

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Popular Name: (4S)-4-phenyl-N-(2,4,5-trichlorophenyl)-4,5-dihydrothiazol-2-amine (4S)-4-phenyl-N-(2,4,5-trichloro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.56 10.1 -6.23 1 2 0 24 357.693 2 ↓

Analogs

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Popular Name: (4R)-N-(4-methylsulfanylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(4-methylsulfanylphenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 9.51 -7.93 1 2 0 24 300.452 3 ↓
Mid Mid (pH 6-8) 4.11 9.95 -30.04 2 2 1 26 301.46 4 ↓

Analogs

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Popular Name: (4S)-N-(4-methylsulfanylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(4-methylsulfanylphenyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 9.51 -7.73 1 2 0 24 300.452 3 ↓
Mid Mid (pH 6-8) 4.11 9.95 -29.71 2 2 1 26 301.46 4 ↓

Analogs

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Popular Name: (4R)-N-(2-isopropylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4R)-N-(2-isopropylphenyl)-4-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.66 10.7 -7.34 1 2 0 24 296.439 3 ↓
Mid Mid (pH 6-8) 4.66 10.85 -27.5 2 2 1 26 297.447 4 ↓

Analogs

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Popular Name: (4S)-N-(2-isopropylphenyl)-4-phenyl-4,5-dihydrothiazol-2-amine (4S)-N-(2-isopropylphenyl)-4-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.66 10.69 -7.32 1 2 0 24 296.439 3 ↓
Mid Mid (pH 6-8) 4.66 10.85 -27.46 2 2 1 26 297.447 4 ↓

Analogs

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Popular Name: (4R)-4-phenyl-N-(2,3,4-trifluorophenyl)-4,5-dihydrothiazol-2-amine (4R)-4-phenyl-N-(2,3,4-trifluoro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.02 8.73 -10.02 1 2 0 24 308.328 2 ↓

Analogs

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Popular Name: (4S)-4-phenyl-N-(2,3,4-trifluorophenyl)-4,5-dihydrothiazol-2-amine (4S)-4-phenyl-N-(2,3,4-trifluoro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.02 8.74 -9.96 1 2 0 24 308.328 2 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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