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Analogs

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Popular Name: 2-(2,4-dioxo-8-thia-1,3-diazaspiro[4.5]decan-3-yl)-N-(2,2,2-trifluoroethyl)acetamide 2-(2,4-dioxo-8-thia-1,3-diazaspi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.69 2.75 -11.83 2 6 0 79 325.312 4 ↓

Analogs

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Popular Name: 2-(1,3-dioxo-8-thia-2,4-diazaspiro[4.5]decan-2-yl)-N,N-diethyl-acetamide 2-(1,3-dioxo-8-thia-2,4-diazaspi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.26 5.29 -13.14 1 6 0 70 299.396 4 ↓

Analogs

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Popular Name: 2-[(2-chloro-6-fluoro-phenyl)methyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2-chloro-6-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.31 6.98 -7.87 1 4 0 49 328.796 2 ↓

Analogs

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Popular Name: 3-(1,3-dioxo-8-thia-2,4-diazaspiro[4.5]decan-2-yl)-N-phenyl-propanamide 3-(1,3-dioxo-8-thia-2,4-diazaspi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.24 5.57 -12.51 2 6 0 79 333.413 4 ↓

Analogs

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Popular Name: 2-(o-tolylmethyl)-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-(o-tolylmethyl)-8-thia-2,4-dia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 7.55 -8.38 1 4 0 49 290.388 2 ↓

Analogs

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Popular Name: 2-[(2S)-2-hydroxy-2-phenyl-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2S)-2-hydroxy-2-phenyl-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 4.18 -8.01 2 5 0 70 306.387 3 ↓

Analogs

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Popular Name: 2-[(2R)-2-hydroxy-2-phenyl-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2R)-2-hydroxy-2-phenyl-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 4.23 -7.57 2 5 0 70 306.387 3 ↓

Analogs

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Popular Name: 2-[(2S)-2-(3-fluorophenyl)-2-hydroxy-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2S)-2-(3-fluorophenyl)-2-hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.11 4.25 -8.27 2 5 0 70 324.377 3 ↓

Analogs

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Popular Name: 2-[(2R)-2-(3-fluorophenyl)-2-hydroxy-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2R)-2-(3-fluorophenyl)-2-hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.11 4.3 -8.33 2 5 0 70 324.377 3 ↓

Analogs

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Popular Name: 3-[(5-chlorothiadiazol-4-yl)methyl]-8-thia-1,3-diazaspiro[4.5]decane-2,4-dione 3-[(5-chlorothiadiazol-4-yl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.19 3.37 -8.83 1 6 0 75 318.811 2 ↓

Analogs

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Popular Name: 2-ethyl-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-ethyl-8-thia-2,4-diazaspiro[4.…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 3.56 -6.64 1 4 0 49 214.29 1 ↓

Analogs

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Popular Name: 2-[(2,5-dimethylphenyl)methyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[(2,5-dimethylphenyl)methyl]-8…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.38 7.7 -6.44 1 4 0 49 304.415 2 ↓

Analogs

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Popular Name: 4-[(1,3-dioxo-8-thia-2,4-diazaspiro[4.5]decan-2-yl)methyl]benzonitrile 4-[(1,3-dioxo-8-thia-2,4-diazasp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 6.98 -8.86 1 5 0 73 301.371 2 ↓

Analogs

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Popular Name: 2-[[4-(difluoromethoxy)phenyl]methyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 6.17 -9.56 1 5 0 59 342.367 4 ↓

Analogs

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Popular Name: 2-benzyl-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-benzyl-8-thia-2,4-diazaspiro[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.56 6.58 -6.79 1 4 0 49 276.361 2 ↓

Analogs

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Popular Name: 2-[2-[(3S,5R)-3,5-dimethyl-1-piperidyl]-2-oxo-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[2-[(3S,5R)-3,5-dimethyl-1-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.14 6.59 -12.72 1 6 0 70 339.461 2 ↓

Analogs

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Popular Name: 2-[2-[(3S,5S)-3,5-dimethyl-1-piperidyl]-2-oxo-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[2-[(3S,5S)-3,5-dimethyl-1-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.14 6.83 -13.03 1 6 0 70 339.461 2 ↓

Analogs

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Popular Name: 2-[2-[(3R,5R)-3,5-dimethyl-1-piperidyl]-2-oxo-ethyl]-8-thia-2,4-diazaspiro[4.5]decane-1,3-dione 2-[2-[(3R,5R)-3,5-dimethyl-1-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.14 6.83 -12.56 1 6 0 70 339.461 2 ↓

Parameters Provided:

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 351331 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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