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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: (6R)-N-[(7-methoxy-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6R)-N-[(7-methoxy-2H-chromen-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 7.18 -61.37 2 6 1 66 313.381 4 ↓
Mid Mid (pH 6-8) 1.66 6.02 -11.62 1 6 0 61 312.373 4 ↓

Analogs

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Popular Name: (6S)-N-[(7-methoxy-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6S)-N-[(7-methoxy-2H-chromen-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 7.18 -61.63 2 6 1 66 313.381 4 ↓
Mid Mid (pH 6-8) 1.66 6 -12.35 1 6 0 61 312.373 4 ↓

Analogs

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Popular Name: (6R)-N-(2H-chromen-3-ylmethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6R)-N-(2H-chromen-3-ylmethyl)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.63 7.87 -58.68 2 5 1 57 283.355 3 ↓
Mid Mid (pH 6-8) 1.63 6.71 -10.08 1 5 0 52 282.347 3 ↓

Analogs

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Popular Name: (6S)-N-(2H-chromen-3-ylmethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6S)-N-(2H-chromen-3-ylmethyl)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.63 7.87 -58.82 2 5 1 57 283.355 3 ↓
Mid Mid (pH 6-8) 1.63 6.69 -10.56 1 5 0 52 282.347 3 ↓

Analogs

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Popular Name: (6R)-N-[(6-chloro-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6R)-N-[(6-chloro-2H-chromen-3-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 8.39 -60.74 2 5 1 57 317.8 3 ↓
Mid Mid (pH 6-8) 2.28 7.24 -9.51 1 5 0 52 316.792 3 ↓

Analogs

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Popular Name: (6S)-N-[(6-chloro-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6S)-N-[(6-chloro-2H-chromen-3-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 8.39 -60.61 2 5 1 57 317.8 3 ↓
Mid Mid (pH 6-8) 2.28 7.21 -9.77 1 5 0 52 316.792 3 ↓

Analogs

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Popular Name: (6R)-N-[(6-chloro-2H-chromen-3-yl)methyl]-2-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin- (6R)-N-[(6-chloro-2H-chromen-3-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 8.28 -61.1 2 5 1 57 331.827 3 ↓
Mid Mid (pH 6-8) 2.37 7.1 -11.12 1 5 0 52 330.819 3 ↓

Analogs

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Popular Name: (6S)-N-[(6-chloro-2H-chromen-3-yl)methyl]-2-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin- (6S)-N-[(6-chloro-2H-chromen-3-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 8.28 -60.93 2 5 1 57 331.827 3 ↓
Mid Mid (pH 6-8) 2.37 7.12 -10.21 1 5 0 52 330.819 3 ↓

Analogs

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Popular Name: (6R)-N-[(7-methoxy-2H-chromen-3-yl)methyl]-2-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin (6R)-N-[(7-methoxy-2H-chromen-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 7.06 -61.75 2 6 1 66 327.408 4 ↓
Mid Mid (pH 6-8) 1.75 5.89 -12.88 1 6 0 61 326.4 4 ↓

Analogs

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Popular Name: (6S)-N-[(7-methoxy-2H-chromen-3-yl)methyl]-2-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin (6S)-N-[(7-methoxy-2H-chromen-3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 7.06 -62 2 6 1 66 327.408 4 ↓
Mid Mid (pH 6-8) 1.75 5.91 -12.48 1 6 0 61 326.4 4 ↓

Analogs

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Popular Name: (6R)-N-(2H-chromen-3-ylmethyl)-2-ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6R)-N-(2H-chromen-3-ylmethyl)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 8.36 -58.8 2 5 1 57 311.409 4 ↓
Mid Mid (pH 6-8) 2.29 7.19 -11.3 1 5 0 52 310.401 4 ↓

Analogs

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Popular Name: (6S)-N-(2H-chromen-3-ylmethyl)-2-ethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6S)-N-(2H-chromen-3-ylmethyl)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 8.36 -58.86 2 5 1 57 311.409 4 ↓
Mid Mid (pH 6-8) 2.29 7.21 -10.66 1 5 0 52 310.401 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6R)-2-ethyl-N-[(7-methoxy-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin- (6R)-2-ethyl-N-[(7-methoxy-2H-ch…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 7.67 -61.49 2 6 1 66 341.435 5 ↓
Mid Mid (pH 6-8) 2.32 6.49 -12.73 1 6 0 61 340.427 5 ↓

Analogs

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Popular Name: (6S)-2-ethyl-N-[(7-methoxy-2H-chromen-3-yl)methyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin- (6S)-2-ethyl-N-[(7-methoxy-2H-ch…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 7.67 -61.76 2 6 1 66 341.435 5 ↓
Mid Mid (pH 6-8) 2.32 6.52 -12.34 1 6 0 61 340.427 5 ↓

Analogs

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Popular Name: (6R)-N-(2H-chromen-3-ylmethyl)-2-isopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6R)-N-(2H-chromen-3-ylmethyl)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 8.82 -58.33 2 5 1 57 325.436 4 ↓
Mid Mid (pH 6-8) 2.77 7.65 -11.14 1 5 0 52 324.428 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6S)-N-(2H-chromen-3-ylmethyl)-2-isopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-amine (6S)-N-(2H-chromen-3-ylmethyl)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 8.82 -58.38 2 5 1 57 325.436 4 ↓
Mid Mid (pH 6-8) 2.77 7.67 -10.48 1 5 0 52 324.428 4 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

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