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Analogs

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Popular Name: 3-methyl-5-(6-quinolyl)imidazol-4-amine 3-methyl-5-(6-quinolyl)imidazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.30 6.43 -8.5 3 4 0 56 226.283 1 ↓
Hi High (pH 8-9.5) 1.30 5.41 -51.69 2 4 0 54 225.275 1 ↓

Analogs

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Popular Name: 3-ethyl-5-(6-quinolyl)imidazol-4-amine 3-ethyl-5-(6-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 7.38 -8.02 3 4 0 56 240.31 2 ↓
Hi High (pH 8-9.5) 1.68 6.36 -50.02 2 4 0 54 239.302 2 ↓

Analogs

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Popular Name: 3-propyl-5-(6-quinolyl)imidazol-4-amine 3-propyl-5-(6-quinolyl)imidazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 8.13 -7.69 3 4 0 56 254.337 3 ↓
Hi High (pH 8-9.5) 2.18 7.11 -49.39 2 4 0 54 253.329 3 ↓

Analogs

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Popular Name: 3-isopropyl-5-(6-quinolyl)imidazol-4-amine 3-isopropyl-5-(6-quinolyl)imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 7.72 -7.83 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 1.97 6.69 -48.1 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 3-tert-butyl-5-(6-quinolyl)imidazol-4-amine 3-tert-butyl-5-(6-quinolyl)imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 8.16 -7.67 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.48 7.13 -45.29 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 3-butyl-5-(6-quinolyl)imidazol-4-amine 3-butyl-5-(6-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.74 8.91 -7.63 3 4 0 56 268.364 4 ↓
Hi High (pH 8-9.5) 2.74 7.89 -49.72 2 4 0 54 267.356 4 ↓

Analogs

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Popular Name: 3-isobutyl-5-(6-quinolyl)imidazol-4-amine 3-isobutyl-5-(6-quinolyl)imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 8.31 -7.5 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.42 7.29 -49.02 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 2,3-dimethyl-5-(6-quinolyl)imidazol-4-amine 2,3-dimethyl-5-(6-quinolyl)imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 6.26 -8.33 3 4 0 56 240.31 1 ↓
Hi High (pH 8-9.5) 1.75 5.29 -49.1 2 4 0 54 239.302 1 ↓

Analogs

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Popular Name: 3-ethyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-ethyl-2-methyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 7.14 -8.02 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 2.12 6.17 -47.76 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 2-methyl-3-propyl-5-(6-quinolyl)imidazol-4-amine 2-methyl-3-propyl-5-(6-quinolyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.9 -7.78 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.62 6.93 -46.95 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 3-isopropyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-isopropyl-2-methyl-5-(6-quinol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 7.79 -7.78 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.42 6.82 -44.87 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 3-tert-butyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-tert-butyl-2-methyl-5-(6-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 8.07 -8.12 3 4 0 56 282.391 2 ↓
Hi High (pH 8-9.5) 2.93 7.1 -42.78 2 4 0 54 281.383 2 ↓

Analogs

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Popular Name: 3-isobutyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-isobutyl-2-methyl-5-(6-quinoly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 8.02 -7.56 3 4 0 56 282.391 3 ↓
Hi High (pH 8-9.5) 2.87 7.3 -46.92 2 4 0 54 281.383 3 ↓

Analogs

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Popular Name: 3-butyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-butyl-2-methyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 8.68 -7.75 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.18 7.71 -47.42 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 3-allyl-5-(6-quinolyl)imidazol-4-amine 3-allyl-5-(6-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 7.93 -7.91 3 4 0 56 252.321 3 ↓
Hi High (pH 8-9.5) 1.94 6.9 -49.36 2 4 0 54 251.313 3 ↓

Analogs

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Popular Name: 3-prop-2-ynyl-5-(6-quinolyl)imidazol-4-amine 3-prop-2-ynyl-5-(6-quinolyl)imid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.89 -8.99 3 4 0 56 250.305 2 ↓
Hi High (pH 8-9.5) 1.46 6.86 -49.21 2 4 0 54 249.297 2 ↓

Analogs

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Popular Name: 3-allyl-2-methyl-5-(6-quinolyl)imidazol-4-amine 3-allyl-2-methyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 7.73 -7.93 3 4 0 56 266.348 3 ↓
Hi High (pH 8-9.5) 2.39 6.76 -47.36 2 4 0 54 265.34 3 ↓

Analogs

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Popular Name: 2-methyl-3-prop-2-ynyl-5-(6-quinolyl)imidazol-4-amine 2-methyl-3-prop-2-ynyl-5-(6-quin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.90 7.7 -9.22 3 4 0 56 264.332 2 ↓
Hi High (pH 8-9.5) 1.90 6.73 -46.9 2 4 0 54 263.324 2 ↓

Analogs

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Popular Name: 2-ethyl-3-methyl-5-(6-quinolyl)imidazol-4-amine 2-ethyl-3-methyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 6.84 -8.02 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 2.25 6.3 -49.06 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 2,3-diethyl-5-(6-quinolyl)imidazol-4-amine 2,3-diethyl-5-(6-quinolyl)imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.71 -7.66 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.62 7.23 -47.75 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 2-ethyl-3-propyl-5-(6-quinolyl)imidazol-4-amine 2-ethyl-3-propyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 8.48 -7.39 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.13 7.99 -46.91 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 2-ethyl-3-isopropyl-5-(6-quinolyl)imidazol-4-amine 2-ethyl-3-isopropyl-5-(6-quinoly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 8.32 -7.38 3 4 0 56 282.391 3 ↓
Hi High (pH 8-9.5) 2.92 7.83 -44.69 2 4 0 54 281.383 3 ↓

Analogs

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Popular Name: 3-allyl-2-ethyl-5-(6-quinolyl)imidazol-4-amine 3-allyl-2-ethyl-5-(6-quinolyl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 8.27 -7.55 3 4 0 56 280.375 4 ↓
Hi High (pH 8-9.5) 2.89 7.78 -47.29 2 4 0 54 279.367 4 ↓

Analogs

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Popular Name: 2-ethyl-3-prop-2-ynyl-5-(6-quinolyl)imidazol-4-amine 2-ethyl-3-prop-2-ynyl-5-(6-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 8.24 -8.76 3 4 0 56 278.359 3 ↓
Hi High (pH 8-9.5) 2.41 8.29 -50.23 2 4 0 54 277.351 3 ↓
Hi High (pH 8-9.5) 2.41 7.75 -46.75 2 4 0 54 277.351 3 ↓

Analogs

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Popular Name: 3-methyl-2-propyl-5-(6-quinolyl)imidazol-4-amine 3-methyl-2-propyl-5-(6-quinolyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 7.62 -7.8 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.81 7.09 -48.89 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 3-ethyl-2-propyl-5-(6-quinolyl)imidazol-4-amine 3-ethyl-2-propyl-5-(6-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 8.49 -7.48 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.18 7.99 -47.68 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 2-isopropyl-3-methyl-5-(6-quinolyl)imidazol-4-amine 2-isopropyl-3-methyl-5-(6-quinol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.49 7.54 -7.8 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.49 6.67 -48.07 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 2-tert-butyl-3-methyl-5-(6-quinolyl)imidazol-4-amine 2-tert-butyl-3-methyl-5-(6-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.07 7.64 -7.63 3 4 0 56 282.391 2 ↓
Hi High (pH 8-9.5) 3.07 6.81 -47.45 2 4 0 54 281.383 2 ↓

Parameters Provided:

ring.id = 359336
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 359336 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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