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Analogs

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Popular Name: 3-methyl-5-(8-quinolyl)imidazol-4-amine 3-methyl-5-(8-quinolyl)imidazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 7.12 -8.81 3 4 0 56 226.283 1 ↓
Hi High (pH 8-9.5) 1.27 6.09 -32.11 2 4 0 54 225.275 1 ↓

Analogs

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Popular Name: 3-ethyl-5-(8-quinolyl)imidazol-4-amine 3-ethyl-5-(8-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.65 7.88 -8.16 3 4 0 56 240.31 2 ↓
Hi High (pH 8-9.5) 1.65 6.85 -31.7 2 4 0 54 239.302 2 ↓

Analogs

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Popular Name: 3-propyl-5-(8-quinolyl)imidazol-4-amine 3-propyl-5-(8-quinolyl)imidazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.15 8.63 -7.84 3 4 0 56 254.337 3 ↓
Hi High (pH 8-9.5) 2.15 7.6 -30.78 2 4 0 54 253.329 3 ↓

Analogs

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Popular Name: 3-isopropyl-5-(8-quinolyl)imidazol-4-amine 3-isopropyl-5-(8-quinolyl)imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 8.21 -7.92 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 1.95 7.18 -29.17 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 3-tert-butyl-5-(8-quinolyl)imidazol-4-amine 3-tert-butyl-5-(8-quinolyl)imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 8.65 -7.7 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.46 7.62 -26.74 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 3-butyl-5-(8-quinolyl)imidazol-4-amine 3-butyl-5-(8-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 9.41 -7.78 3 4 0 56 268.364 4 ↓
Hi High (pH 8-9.5) 2.71 8.38 -31.16 2 4 0 54 267.356 4 ↓

Analogs

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Popular Name: 3-isobutyl-5-(8-quinolyl)imidazol-4-amine 3-isobutyl-5-(8-quinolyl)imidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 8.98 -7.21 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.40 7.96 -30.51 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 2,3-dimethyl-5-(8-quinolyl)imidazol-4-amine 2,3-dimethyl-5-(8-quinolyl)imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 6.94 -8.65 3 4 0 56 240.31 1 ↓
Hi High (pH 8-9.5) 1.72 5.96 -29.08 2 4 0 54 239.302 1 ↓

Analogs

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Popular Name: 3-ethyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-ethyl-2-methyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 7.81 -8.18 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 2.10 6.83 -27.39 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 2-methyl-3-propyl-5-(8-quinolyl)imidazol-4-amine 2-methyl-3-propyl-5-(8-quinolyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.60 8.57 -7.88 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.60 7.59 -26.24 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 3-isopropyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-isopropyl-2-methyl-5-(8-quinol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 8.47 -7.86 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.39 7.49 -25.43 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 3-tert-butyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-tert-butyl-2-methyl-5-(8-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 8.72 -8.54 3 4 0 56 282.391 2 ↓
Hi High (pH 8-9.5) 2.91 7.74 -23.52 2 4 0 54 281.383 2 ↓

Analogs

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Popular Name: 3-isobutyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-isobutyl-2-methyl-5-(8-quinoly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 8.97 -7.17 3 4 0 56 282.391 3 ↓
Hi High (pH 8-9.5) 2.84 7.73 -26.73 2 4 0 54 281.383 3 ↓

Analogs

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Popular Name: 3-butyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-butyl-2-methyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 9.35 -7.75 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.16 8.37 -26.75 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 3-allyl-5-(8-quinolyl)imidazol-4-amine 3-allyl-5-(8-quinolyl)imidazol-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 8.42 -7.98 3 4 0 56 252.321 3 ↓
Hi High (pH 8-9.5) 1.92 7.4 -30.99 2 4 0 54 251.313 3 ↓

Analogs

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Popular Name: 3-prop-2-ynyl-5-(8-quinolyl)imidazol-4-amine 3-prop-2-ynyl-5-(8-quinolyl)imid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.43 8.58 -9.22 3 4 0 56 250.305 2 ↓
Hi High (pH 8-9.5) 1.43 7.55 -29.03 2 4 0 54 249.297 2 ↓

Analogs

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Popular Name: 3-allyl-2-methyl-5-(8-quinolyl)imidazol-4-amine 3-allyl-2-methyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 8.41 -7.89 3 4 0 56 266.348 3 ↓
Hi High (pH 8-9.5) 2.37 7.44 -26.46 2 4 0 54 265.34 3 ↓

Analogs

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Popular Name: 2-methyl-3-prop-2-ynyl-5-(8-quinolyl)imidazol-4-amine 2-methyl-3-prop-2-ynyl-5-(8-quin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.88 8.39 -9 3 4 0 56 264.332 2 ↓
Hi High (pH 8-9.5) 1.88 7.41 -12.19 2 4 0 54 263.324 2 ↓

Analogs

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Popular Name: 2-ethyl-3-methyl-5-(8-quinolyl)imidazol-4-amine 2-ethyl-3-methyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 7.32 -8.02 3 4 0 56 254.337 2 ↓
Hi High (pH 8-9.5) 2.22 6.78 -29.72 2 4 0 54 253.329 2 ↓

Analogs

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Popular Name: 2,3-diethyl-5-(8-quinolyl)imidazol-4-amine 2,3-diethyl-5-(8-quinolyl)imidaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.60 8.2 -7.61 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.60 7.7 -28.4 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 2-ethyl-3-propyl-5-(8-quinolyl)imidazol-4-amine 2-ethyl-3-propyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.10 8.95 -7.29 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.10 8.46 -27.28 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 2-ethyl-3-isopropyl-5-(8-quinolyl)imidazol-4-amine 2-ethyl-3-isopropyl-5-(8-quinoly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 8.81 -7.28 3 4 0 56 282.391 3 ↓
Hi High (pH 8-9.5) 2.90 8.3 -25.92 2 4 0 54 281.383 3 ↓

Analogs

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Popular Name: 3-allyl-2-ethyl-5-(8-quinolyl)imidazol-4-amine 3-allyl-2-ethyl-5-(8-quinolyl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 8.76 -7.38 3 4 0 56 280.375 4 ↓
Hi High (pH 8-9.5) 2.87 8.25 -27.25 2 4 0 54 279.367 4 ↓

Analogs

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Popular Name: 2-ethyl-3-prop-2-ynyl-5-(8-quinolyl)imidazol-4-amine 2-ethyl-3-prop-2-ynyl-5-(8-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.38 8.73 -8.5 3 4 0 56 278.359 3 ↓
Hi High (pH 8-9.5) 2.38 8.77 -39.43 2 4 0 54 277.351 3 ↓
Hi High (pH 8-9.5) 2.38 8.22 -11.08 2 4 0 54 277.351 3 ↓

Analogs

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Popular Name: 3-methyl-2-propyl-5-(8-quinolyl)imidazol-4-amine 3-methyl-2-propyl-5-(8-quinolyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.78 8.1 -7.8 3 4 0 56 268.364 3 ↓
Hi High (pH 8-9.5) 2.78 7.56 -29.26 2 4 0 54 267.356 3 ↓

Analogs

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Popular Name: 3-ethyl-2-propyl-5-(8-quinolyl)imidazol-4-amine 3-ethyl-2-propyl-5-(8-quinolyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 9.18 -7.55 3 4 0 56 282.391 4 ↓
Hi High (pH 8-9.5) 3.16 8.67 -27.21 2 4 0 54 281.383 4 ↓

Analogs

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Popular Name: 2-isopropyl-3-methyl-5-(8-quinolyl)imidazol-4-amine 2-isopropyl-3-methyl-5-(8-quinol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.47 8.03 -7.79 3 4 0 56 268.364 2 ↓
Hi High (pH 8-9.5) 2.47 7.15 -28.13 2 4 0 54 267.356 2 ↓

Analogs

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Popular Name: 3-ethyl-2-isopropyl-5-(8-quinolyl)imidazol-4-amine 3-ethyl-2-isopropyl-5-(8-quinoly…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 9.21 -7.5 3 4 0 56 282.391 3 ↓
Hi High (pH 8-9.5) 2.84 8.32 -25.33 2 4 0 54 281.383 3 ↓

Analogs

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Popular Name: 2-tert-butyl-3-methyl-5-(8-quinolyl)imidazol-4-amine 2-tert-butyl-3-methyl-5-(8-quino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 8.33 -7.81 3 4 0 56 282.391 2 ↓
Hi High (pH 8-9.5) 3.05 7.48 -26.25 2 4 0 54 281.383 2 ↓

Parameters Provided:

ring.id = 359338
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 359338 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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