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Popular Name: N-[2-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]ethyl]-3-methoxy-benzamide N-[2-[4-(1,2-benzoxazol-3-yl)pip…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
DRD4-2-E Dopamine D4 Receptor (cluster #2 Of 4), Eukaryotic Eukaryotes 2 0.43 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
DRD4_RAT P30729 Dopamine D4 Receptor, Rat 1.93 0.44 Binding ≤ 1μM
DRD4_RAT P30729 Dopamine D4 Receptor, Rat 1.93 0.44 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 6.39 -18.64 1 7 0 71 380.448 6 ↓
Mid Mid (pH 6-8) 2.70 8.59 -61.27 2 7 1 72 381.456 6 ↓

Parameters Provided:

ring.id = 366016
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 366016 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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