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Analogs

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Popular Name: 3-chloro-7,8-dihydro-5H-pyrano[4,3-c]pyridazine 3-chloro-7,8-dihydro-5H-pyrano[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 2.12 -7.38 0 3 0 35 170.599 0 ↓

Analogs

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Popular Name: 7,8-dihydro-5H-pyrano[4,3-c]pyridazin-3-amine 7,8-dihydro-5H-pyrano[4,3-c]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.39 0.64 -29.44 3 4 1 62 152.177 0 ↓
Mid Mid (pH 6-8) 0.39 0.47 -9 2 4 0 61 151.169 0 ↓
Mid Mid (pH 6-8) 0.39 0.58 -28.15 3 4 1 62 152.177 0 ↓

Analogs

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Popular Name: N-methyl-7,8-dihydro-5H-pyrano[4,3-c]pyridazin-3-amine N-methyl-7,8-dihydro-5H-pyrano[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.77 1.38 -9.02 1 4 0 47 165.196 1 ↓
Mid Mid (pH 6-8) 0.77 1.56 -27.43 2 4 1 48 166.204 1 ↓
Mid Mid (pH 6-8) 0.77 1.49 -26.98 2 4 1 48 166.204 1 ↓

Analogs

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Popular Name: N-ethyl-7,8-dihydro-5H-pyrano[4,3-c]pyridazin-3-amine N-ethyl-7,8-dihydro-5H-pyrano[4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.14 2.2 -8.48 1 4 0 47 179.223 2 ↓
Mid Mid (pH 6-8) 1.14 2.37 -26.89 2 4 1 48 180.231 2 ↓
Mid Mid (pH 6-8) 1.14 2.31 -26.79 2 4 1 48 180.231 2 ↓

Analogs

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Popular Name: N-propyl-7,8-dihydro-5H-pyrano[4,3-c]pyridazin-3-amine N-propyl-7,8-dihydro-5H-pyrano[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 2.97 -8.13 1 4 0 47 193.25 3 ↓
Mid Mid (pH 6-8) 1.64 3.13 -27.11 2 4 1 48 194.258 3 ↓
Mid Mid (pH 6-8) 1.64 3.08 -26.83 2 4 1 48 194.258 3 ↓

Analogs

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Popular Name: 7,8-dihydro-5H-pyrano[4,3-c]pyridazin-3-ylhydrazine 7,8-dihydro-5H-pyrano[4,3-c]pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.15 0.3 -10.27 3 5 0 73 166.184 1 ↓
Mid Mid (pH 6-8) 0.15 0.41 -28.84 4 5 1 74 167.192 1 ↓

Parameters Provided:

ring.id = 370689
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 370689 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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