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64976683

Analogs

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Popular Name: N-[5-chloro-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acetamide N-[5-chloro-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	10.63	-21.4	1	7	0	82	455.923	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.57	11.16	-55.26	2	7	1	83	456.931	7	↓ MOL2 SDF SMILES Flexibase

64976684

Analogs

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Popular Name: N-[5-chloro-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3,4-dimethylphenoxy)acetamide N-[5-chloro-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	11.18	-21.56	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.97	11.71	-55.3	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976685

Analogs

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Popular Name: N-[5-chloro-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-fluorophenoxy)acetamide N-[5-chloro-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.26	10.02	-25.29	1	7	0	82	459.886	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.26	10.55	-59.34	2	7	1	83	460.894	7	↓ MOL2 SDF SMILES Flexibase

64976687

Analogs

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Popular Name: (2S)-N-[5-chloro-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2S)-N-[5-chloro-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.01	11.08	-20.48	1	7	0	82	469.95	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.01	11.61	-54.92	2	7	1	83	470.958	8	↓ MOL2 SDF SMILES Flexibase

64976688

Analogs

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Popular Name: (2R)-N-[5-chloro-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2R)-N-[5-chloro-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.01	11.11	-20.9	1	7	0	82	469.95	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.01	11.64	-54.93	2	7	1	83	470.958	8	↓ MOL2 SDF SMILES Flexibase

64976716

Analogs

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Popular Name: N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[5-methyl-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.92	10.1	-20.55	1	7	0	82	421.478	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.92	10.64	-51.87	2	7	1	83	422.486	7	↓ MOL2 SDF SMILES Flexibase

64976717

Analogs

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Popular Name: N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-methylphenoxy)acetamide N-[5-methyl-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	10.82	-20.27	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.32	11.36	-51.52	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976718

Analogs

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Popular Name: N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acetamide N-[5-methyl-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	10.78	-20.86	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.34	11.31	-52.09	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976719

Analogs

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Popular Name: 2-(3,4-dimethylphenoxy)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(3,4-dimethylphenoxy)-N-[5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	11.32	-20.71	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.74	11.86	-52.09	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976720

Analogs

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Popular Name: 2-(4-methoxyphenoxy)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(4-methoxyphenoxy)-N-[5-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	9.39	-21.17	1	8	0	91	451.504	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.97	9.93	-52.63	2	8	1	92	452.512	8	↓ MOL2 SDF SMILES Flexibase

64976721

Analogs

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Popular Name: 2-(2-fluorophenoxy)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(2-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.03	10.17	-24.38	1	7	0	82	439.468	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.03	10.71	-55.99	2	7	1	83	440.476	7	↓ MOL2 SDF SMILES Flexibase

64976722

Analogs

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Popular Name: 2-(4-fluorophenoxy)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(4-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.08	10.17	-20.35	1	7	0	82	439.468	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.08	10.71	-52.27	2	7	1	83	440.476	7	↓ MOL2 SDF SMILES Flexibase

64976723

Analogs

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Popular Name: 2-(2-chlorophenoxy)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(2-chlorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	10.64	-22.47	1	7	0	82	455.923	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.54	11.18	-53.94	2	7	1	83	456.931	7	↓ MOL2 SDF SMILES Flexibase

64976727

Analogs

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Popular Name: (2S)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2S)-N-[5-methyl-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	11.24	-19.74	1	7	0	82	449.532	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.78	11.75	-51.71	2	7	1	83	450.54	8	↓ MOL2 SDF SMILES Flexibase

64976728

Analogs

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Popular Name: (2R)-N-[5-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2R)-N-[5-methyl-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	11.27	-20.31	1	7	0	82	449.532	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.78	11.8	-51.76	2	7	1	83	450.54	8	↓ MOL2 SDF SMILES Flexibase

64976759

Analogs

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Popular Name: N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[4-methyl-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.92	10.1	-20.27	1	7	0	82	421.478	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.92	10.64	-51.73	2	7	1	83	422.486	7	↓ MOL2 SDF SMILES Flexibase

64976760

Analogs

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Popular Name: N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acetamide N-[4-methyl-2-[(5-oxothiazolo[3,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.34	10.77	-20.55	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.34	11.3	-51.89	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976761

Analogs

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Popular Name: 2-(3,4-dimethylphenoxy)-N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(3,4-dimethylphenoxy)-N-[4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	11.32	-20.49	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.74	11.86	-51.9	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976762

Analogs

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Popular Name: 2-(2-fluorophenoxy)-N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(2-fluorophenoxy)-N-[4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.03	10.17	-24.11	1	7	0	82	439.468	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.03	10.71	-55.8	2	7	1	83	440.476	7	↓ MOL2 SDF SMILES Flexibase

64976763

Analogs

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Popular Name: 2-(2-chlorophenoxy)-N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acetamide 2-(2-chlorophenoxy)-N-[4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	10.64	-22.19	1	7	0	82	455.923	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.54	11.18	-53.75	2	7	1	83	456.931	7	↓ MOL2 SDF SMILES Flexibase

64976767

Analogs

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Popular Name: (2S)-N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2S)-N-[4-methyl-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	11.24	-19.4	1	7	0	82	449.532	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.78	11.77	-51.49	2	7	1	83	450.54	8	↓ MOL2 SDF SMILES Flexibase

64976768

Analogs

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Popular Name: (2R)-N-[4-methyl-2-[(5-oxothiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanamide (2R)-N-[4-methyl-2-[(5-oxothiazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	11.26	-19.96	1	7	0	82	449.532	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.78	11.79	-51.5	2	7	1	83	450.54	8	↓ MOL2 SDF SMILES Flexibase

64976797

Analogs

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Popular Name: N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[5-methyl-2-[(3-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	10.7	-19.59	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.14	11.24	-50.6	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976798

Analogs

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Popular Name: N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-methylphenoxy)acet N-[5-methyl-2-[(3-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	11.41	-19.3	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.54	11.95	-50.25	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976799

Analogs

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Popular Name: N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acet N-[5-methyl-2-[(3-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	11.38	-19.83	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.56	11.91	-50.86	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976800

Analogs

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Popular Name: N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(4-methylphenoxy)acet N-[5-methyl-2-[(3-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.58	11.38	-19.62	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.58	11.91	-50.68	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976801

Analogs

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Popular Name: 2-(3,4-dimethylphenoxy)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl] 2-(3,4-dimethylphenoxy)-N-[5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.96	11.91	-19.8	1	7	0	82	463.559	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.96	12.45	-50.82	2	7	1	83	464.567	7	↓ MOL2 SDF SMILES Flexibase

64976802

Analogs

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Popular Name: 2-(2-fluorophenoxy)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(2-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.25	10.76	-23.44	1	7	0	82	453.495	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.25	11.3	-54.71	2	7	1	83	454.503	7	↓ MOL2 SDF SMILES Flexibase

64976803

Analogs

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Popular Name: 2-(4-fluorophenoxy)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(4-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	10.77	-19.37	1	7	0	82	453.495	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.30	11.31	-51.03	2	7	1	83	454.503	7	↓ MOL2 SDF SMILES Flexibase

64976804

Analogs

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Popular Name: 2-(2-chlorophenoxy)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(2-chlorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	11.24	-21.43	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.77	11.78	-52.75	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976805

Analogs

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Popular Name: 2-(4-chlorophenoxy)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(4-chlorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.81	11.22	-18.86	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.81	11.76	-50.41	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976808

Analogs

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Popular Name: (2S)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2S)-N-[5-methyl-2-[(3-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.00	11.83	-18.74	1	7	0	82	463.559	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.00	12.36	-50.37	2	7	1	83	464.567	8	↓ MOL2 SDF SMILES Flexibase

64976809

Analogs

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Popular Name: (2R)-N-[5-methyl-2-[(3-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2R)-N-[5-methyl-2-[(3-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.00	11.86	-19.33	1	7	0	82	463.559	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.00	12.39	-50.45	2	7	1	83	464.567	8	↓ MOL2 SDF SMILES Flexibase

64976821

Analogs

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Popular Name: N-[5-chloro-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[5-chloro-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	10.76	-20.24	1	7	0	82	455.923	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.37	11.3	-52.86	2	7	1	83	456.931	7	↓ MOL2 SDF SMILES Flexibase

64976822

Analogs

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Popular Name: N-[5-chloro-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-methylphenoxy)acet N-[5-chloro-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	11.49	-20.06	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.77	12.02	-52.53	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976823

Analogs

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Popular Name: N-[5-chloro-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acet N-[5-chloro-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.79	11.45	-20.49	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.79	11.98	-53.07	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976824

Analogs

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Popular Name: (2S)-N-[5-chloro-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2S)-N-[5-chloro-2-[(2-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.23	11.91	-19.51	1	7	0	82	483.977	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.23	12.44	-52.75	2	7	1	83	484.985	8	↓ MOL2 SDF SMILES Flexibase

64976825

Analogs

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Popular Name: (2R)-N-[5-chloro-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2R)-N-[5-chloro-2-[(2-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.23	11.93	-19.9	1	7	0	82	483.977	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.23	12.47	-52.67	2	7	1	83	484.985	8	↓ MOL2 SDF SMILES Flexibase

64976847

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[5-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	10.93	-19.56	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.14	11.47	-49.65	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976848

Analogs

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Popular Name: N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-methylphenoxy)acet N-[5-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	11.64	-19.3	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.54	12.18	-49.27	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976849

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(3-methylphenoxy)acet N-[5-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.56	11.61	-19.84	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.56	12.14	-49.76	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976850

Analogs

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Popular Name: N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(4-methylphenoxy)acet N-[5-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.58	11.61	-19.6	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.58	12.14	-49.63	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

64976851

Analogs

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Popular Name: 2-(3,4-dimethylphenoxy)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl] 2-(3,4-dimethylphenoxy)-N-[5-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.96	12.14	-19.76	1	7	0	82	463.559	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.96	12.68	-49.82	2	7	1	83	464.567	7	↓ MOL2 SDF SMILES Flexibase

64976852

Analogs

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Popular Name: 2-(2-fluorophenoxy)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(2-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.25	10.99	-23.4	1	7	0	82	453.495	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.25	11.53	-53.68	2	7	1	83	454.503	7	↓ MOL2 SDF SMILES Flexibase

64976853

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Popular Name: 2-(4-fluorophenoxy)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(4-fluorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	11	-19.36	1	7	0	82	453.495	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.30	11.54	-50.14	2	7	1	83	454.503	7	↓ MOL2 SDF SMILES Flexibase

64976854

Analogs

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Popular Name: 2-(4-chlorophenoxy)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]acet 2-(4-chlorophenoxy)-N-[5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.81	11.45	-18.9	1	7	0	82	469.95	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.81	11.99	-49.5	2	7	1	83	470.958	7	↓ MOL2 SDF SMILES Flexibase

64976855

Analogs

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Popular Name: (2S)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2S)-N-[5-methyl-2-[(2-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.00	12.06	-18.83	1	7	0	82	463.559	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.00	12.58	-49.37	2	7	1	83	464.567	8	↓ MOL2 SDF SMILES Flexibase

64976856

Analogs

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Popular Name: (2R)-N-[5-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-butanami (2R)-N-[5-methyl-2-[(2-methyl-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.00	12.09	-19.34	1	7	0	82	463.559	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.00	12.62	-49.5	2	7	1	83	464.567	8	↓ MOL2 SDF SMILES Flexibase

64976880

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-phenoxy-acetamide N-[4-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	10.93	-19.27	1	7	0	82	435.505	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.14	11.47	-49.48	2	7	1	83	436.513	7	↓ MOL2 SDF SMILES Flexibase

64976881

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-methyl-2-[(2-methyl-5-oxo-thiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]-2-(2-methylphenoxy)acet N-[4-methyl-2-[(2-methyl-5-oxo-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	11.64	-19.02	1	7	0	82	449.532	7	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.54	12.18	-49.06	2	7	1	83	450.54	7	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
<script type="text/javascript">
    window.zinc.embed('zinc-link', {
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