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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: N-[[4-(difluoromethoxy)phenyl]methyl]-N-methyl-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[[4-(difluoromethoxy)phenyl]me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 7.08 -25.47 0 6 0 64 365.361 5 ↓
Lo Low (pH 4.5-6) 1.53 7.57 -56.01 1 6 1 65 366.369 5 ↓

Analogs

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Popular Name: N-[(1S)-1-(2-bromophenyl)ethyl]-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(1S)-1-(2-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 7.23 -14.61 1 5 0 63 378.251 3 ↓
Lo Low (pH 4.5-6) 2.46 7.72 -43.2 2 5 1 65 379.259 3 ↓

Analogs

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Popular Name: N-[(1R)-1-(2-bromophenyl)ethyl]-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(1R)-1-(2-bromophenyl)ethyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 7.19 -14.63 1 5 0 63 378.251 3 ↓
Lo Low (pH 4.5-6) 2.46 7.68 -43.16 2 5 1 65 379.259 3 ↓

Analogs

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Popular Name: N-methyl-5-oxo-N-[[4-(trifluoromethyl)phenyl]methyl]thiazolo[3,2-a]pyrimidine-6-carboxamide N-methyl-5-oxo-N-[[4-(trifluorom…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.81 8.5 -20.91 0 5 0 55 367.352 4 ↓
Lo Low (pH 4.5-6) 1.81 8.99 -52.94 1 5 1 56 368.36 4 ↓

Analogs

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Popular Name: N-[(1R)-1-(3,4-diethoxyphenyl)ethyl]-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(1R)-1-(3,4-diethoxyphenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 7.71 -16.51 1 7 0 82 387.461 7 ↓
Lo Low (pH 4.5-6) 2.10 8.2 -46.14 2 7 1 83 388.469 7 ↓

Analogs

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Popular Name: N-[(1S)-1-(3,4-diethoxyphenyl)ethyl]-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(1S)-1-(3,4-diethoxyphenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 7.71 -16.32 1 7 0 82 387.461 7 ↓
Lo Low (pH 4.5-6) 2.10 8.2 -45.92 2 7 1 83 388.469 7 ↓

Analogs

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-N-methyl-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 6.71 -25.35 0 7 0 73 359.407 5 ↓
Lo Low (pH 4.5-6) 0.56 7.2 -56.44 1 7 1 74 360.415 5 ↓

Analogs

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Popular Name: N-[(2,3-dichlorophenyl)methyl]-N-methyl-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(2,3-dichlorophenyl)methyl]-N…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 8.27 -16.9 0 5 0 55 368.245 3 ↓
Lo Low (pH 4.5-6) 2.17 8.76 -44.71 1 5 1 56 369.253 3 ↓

Analogs

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-N-ethyl-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.94 7.55 -23.27 0 7 0 73 373.434 6 ↓
Lo Low (pH 4.5-6) 0.94 8.03 -52.8 1 7 1 74 374.442 6 ↓

Analogs

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Popular Name: N-[[4-(difluoromethoxy)-3-methoxy-phenyl]methyl]-5-oxo-thiazolo[3,2-a]pyrimidine-6-carboxamide N-[[4-(difluoromethoxy)-3-methox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.35 5.31 -17.57 1 7 0 82 381.36 6 ↓
Lo Low (pH 4.5-6) 1.35 5.8 -47.1 2 7 1 83 382.368 6 ↓

Analogs

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 9.49 -15.62 1 7 0 90 399.472 7 ↓
Lo Low (pH 4.5-6) 1.44 9.98 -45.62 2 7 1 91 400.48 7 ↓

Analogs

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 9.54 -15.76 1 7 0 90 399.472 7 ↓
Lo Low (pH 4.5-6) 1.44 10.03 -45.15 2 7 1 91 400.48 7 ↓

Analogs

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 9.61 -18.95 1 7 0 90 385.445 7 ↓
Lo Low (pH 4.5-6) 0.99 10.1 -44.59 2 7 1 91 386.453 7 ↓

Analogs

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Popular Name: isopropyl isopropyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 9.59 -18.64 1 7 0 90 385.445 7 ↓
Lo Low (pH 4.5-6) 0.99 10.08 -44.06 2 7 1 91 386.453 7 ↓

Analogs

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Popular Name: 5-oxo-N-(p-tolylmethyl)thiazolo[3,2-a]pyrimidine-6-carboxamide 5-oxo-N-(p-tolylmethyl)thiazolo[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 6.51 -14.08 1 5 0 63 299.355 3 ↓
Lo Low (pH 4.5-6) 1.59 7 -42.28 2 5 1 65 300.363 3 ↓

Parameters Provided:

ring.id = 38083
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 38083 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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