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Popular Name: N-[(1S)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine N-[(1S)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 4.37 -4.82 1 3 0 38 177.251 4 ↓

Analogs

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Popular Name: N-[(1R)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine N-[(1R)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 4.37 -4.82 1 3 0 38 177.251 4 ↓

Analogs

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Popular Name: N-[(1S)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine N-[(1S)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 4.44 -4.77 1 3 0 38 191.278 5 ↓

Analogs

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Popular Name: N-[(1R)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine N-[(1R)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 4.85 -4.81 1 3 0 38 191.278 5 ↓

Analogs

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Popular Name: 3-[[(1S)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carbothioamide 3-[[(1S)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 3.99 -12.3 3 4 0 64 236.344 5 ↓

Analogs

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Popular Name: 3-[[(1R)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carbothioamide 3-[[(1R)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 4.09 -12.72 3 4 0 64 236.344 5 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine 6-chloro-N-[(1S)-2-cyclopropyl-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 4.79 -4.15 1 3 0 38 211.696 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine 6-chloro-N-[(1R)-2-cyclopropyl-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 4.79 -4.14 1 3 0 38 211.696 4 ↓

Analogs

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Popular Name: 3-chloro-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine 3-chloro-N-[(1S)-2-cyclopropyl-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 5.31 -5.04 1 3 0 38 211.696 4 ↓

Analogs

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Popular Name: 3-chloro-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]pyrazin-2-amine 3-chloro-N-[(1R)-2-cyclopropyl-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 5.39 -5.07 1 3 0 38 211.696 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine 6-chloro-N-[(1S)-1-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 4.93 -4.19 1 3 0 38 225.723 5 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine 6-chloro-N-[(1R)-1-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 5.26 -4.17 1 3 0 38 225.723 5 ↓

Analogs

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Popular Name: 3-chloro-N-[(1S)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine 3-chloro-N-[(1S)-1-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.13 -4.75 1 3 0 38 225.723 5 ↓

Analogs

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Popular Name: 3-chloro-N-[(1R)-1-(cyclopropylmethyl)propyl]pyrazin-2-amine 3-chloro-N-[(1R)-1-(cyclopropylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.21 -4.8 1 3 0 38 225.723 5 ↓

Analogs

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Popular Name: 3-[[(1S)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carboxylic 3-[[(1S)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 5.62 -50.63 1 5 -1 78 220.252 5 ↓

Analogs

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Popular Name: 3-[[(1R)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carboxylic 3-[[(1R)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 5.69 -50.87 1 5 -1 78 220.252 5 ↓

Analogs

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Popular Name: 3-[[(1S)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carbonitrile 3-[[(1S)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 5.23 -7.17 1 4 0 62 202.261 4 ↓

Analogs

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Popular Name: 3-[[(1R)-2-cyclopropyl-1-methyl-ethyl]amino]pyrazine-2-carbonitrile 3-[[(1R)-2-cyclopropyl-1-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 5.23 -7.19 1 4 0 62 202.261 4 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carbonitrile 3-[[(1S)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 6.04 -7.03 1 4 0 62 216.288 5 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carbonitrile 3-[[(1R)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 6.04 -7.06 1 4 0 62 216.288 5 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carbothioamide 3-[[(1S)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 4.67 -12.2 3 4 0 64 250.371 6 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carbothioamide 3-[[(1R)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 4.74 -12.44 3 4 0 64 250.371 6 ↓

Analogs

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Popular Name: 3-[[(1S)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carboxylic 3-[[(1S)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 6.27 -51.23 1 5 -1 78 234.279 6 ↓

Analogs

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Popular Name: 3-[[(1R)-1-(cyclopropylmethyl)propyl]amino]pyrazine-2-carboxylic 3-[[(1R)-1-(cyclopropylmethyl)pr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 6.34 -51.38 1 5 -1 78 234.279 6 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

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SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 387244 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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