ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

69667836

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4,5-dihydrothiazol-2-amine N-[(1S)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.87	5.52	-26.02	2	2	1	26	185.316	4	↓ MOL2 SDF SMILES Flexibase

69667839

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4,5-dihydrothiazol-2-amine N-[(1R)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.87	5.52	-25.99	2	2	1	26	185.316	4	↓ MOL2 SDF SMILES Flexibase

69667842

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	7.04	-24.48	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667846

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	7.04	-24.5	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667849

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	7.12	-24.75	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667854

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	7.12	-24.75	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667865

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-5-methyl-4,5-dihydrothiazol-2-amine (5R)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	6.23	-25.24	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667869

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-5-methyl-4,5-dihydrothiazol-2-amine (5S)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	6.3	-25.72	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667871

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-5-methyl-4,5-dihydrothiazol-2-amine (5R)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	6.3	-25.52	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667876

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-5-methyl-4,5-dihydrothiazol-2-amine (5S)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	6.3	-25.69	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667885

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	8.31	-25.12	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667888

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	8.33	-25.09	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667891

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	8.39	-25.48	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667894

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	8.41	-25.4	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667898

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4,4-dimethyl-5H-thiazol-2-amine N-[(1S)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.67	6.88	-23.63	2	2	1	26	213.37	4	↓ MOL2 SDF SMILES Flexibase

69667901

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4,4-dimethyl-5H-thiazol-2-amine N-[(1R)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.67	6.96	-23.84	2	2	1	26	213.37	4	↓ MOL2 SDF SMILES Flexibase

69667904

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-methyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.20	6.25	-25.01	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667909

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4-methyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.20	6.32	-24.88	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667916

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-methyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.20	6.33	-25.24	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667921

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4-methyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-2-cyclopropyl-1-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.20	6.32	-24.87	2	2	1	26	199.343	4	↓ MOL2 SDF SMILES Flexibase

69667934

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-2-cyclopropyl-1-methyl-ethyl]-4,4-diethyl-5H-thiazol-2-amine N-[(1S)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.11	-23.55	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667939

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-2-cyclopropyl-1-methyl-ethyl]-4,4-diethyl-5H-thiazol-2-amine N-[(1R)-2-cyclopropyl-1-methyl-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.18	-23.78	2	2	1	26	241.424	6	↓ MOL2 SDF SMILES Flexibase

69667959

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-(cyclopropylmethyl)propyl]-4,5-dihydrothiazol-2-amine N-[(1S)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	5.61	-25.96	2	2	1	26	199.343	5	↓ MOL2 SDF SMILES Flexibase

69667962

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(cyclopropylmethyl)propyl]-4,5-dihydrothiazol-2-amine N-[(1R)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	5.69	-26.12	2	2	1	26	199.343	5	↓ MOL2 SDF SMILES Flexibase

69667965

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.27	7.13	-24.31	2	2	1	26	227.397	6	↓ MOL2 SDF SMILES Flexibase

69667969

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.27	7.13	-24.47	2	2	1	26	227.397	6	↓ MOL2 SDF SMILES Flexibase

69667973

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.27	7.22	-24.7	2	2	1	26	227.397	6	↓ MOL2 SDF SMILES Flexibase

69667978

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-ethyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.27	7.22	-24.56	2	2	1	26	227.397	6	↓ MOL2 SDF SMILES Flexibase

69667983

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-N-[(1S)-1-(cyclopropylmethyl)propyl]-5-methyl-4,5-dihydrothiazol-2-amine (5S)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.33	-25.16	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667986

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5S)-N-[(1R)-1-(cyclopropylmethyl)propyl]-5-methyl-4,5-dihydrothiazol-2-amine (5S)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.4	-25.32	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667990

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-N-[(1S)-1-(cyclopropylmethyl)propyl]-5-methyl-4,5-dihydrothiazol-2-amine (5R)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.33	-25.31	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667995

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5R)-N-[(1R)-1-(cyclopropylmethyl)propyl]-5-methyl-4,5-dihydrothiazol-2-amine (5R)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.4	-25.51	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69667998

Analogs

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Popular Name: N-[(1S)-1-(cyclopropylmethyl)propyl]-4,4-dimethyl-5H-thiazol-2-amine N-[(1S)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.21	6.98	-23.58	2	2	1	26	227.397	5	↓ MOL2 SDF SMILES Flexibase

69668003

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(cyclopropylmethyl)propyl]-4,4-dimethyl-5H-thiazol-2-amine N-[(1R)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.21	7.06	-23.74	2	2	1	26	227.397	5	↓ MOL2 SDF SMILES Flexibase

69668008

Analogs

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Popular Name: (4R)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-methyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	6.35	-24.98	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69668012

Analogs

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Popular Name: (4R)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-methyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	6.43	-25.04	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69668016

Analogs

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Popular Name: (4S)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-methyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	6.34	-24.55	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

69668021

Analogs

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Popular Name: (4S)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-methyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	6.41	-24.69	2	2	1	26	213.37	5	↓ MOL2 SDF SMILES Flexibase

70103618

Analogs

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Popular Name: (4R)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	8.42	-24.96	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

70103619

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4R)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4R)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	8.5	-25.41	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

70103620

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1S)-1-(cyclopropylmethyl)propyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1S)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	8.43	-25.11	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

70103621

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4S)-N-[(1R)-1-(cyclopropylmethyl)propyl]-4-isobutyl-4,5-dihydrothiazol-2-amine (4S)-N-[(1R)-1-(cyclopropylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	8.51	-25.21	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

70103638

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-(cyclopropylmethyl)propyl]-4,4-diethyl-5H-thiazol-2-amine N-[(1S)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.22	8.22	-23.49	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

70103639

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(cyclopropylmethyl)propyl]-4,4-diethyl-5H-thiazol-2-amine N-[(1R)-1-(cyclopropylmethyl)pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.22	8.21	-23.72	2	2	1	26	255.451	7	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
<script type="text/javascript">
    window.zinc.embed('zinc-link', {
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