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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 2-[4-[(1R)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridine-3-carbaldehyde 2-[4-[(1R)-1-methylpropyl]pipera…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 9.58 -40.6 1 5 1 42 287.387 4 ↓
Hi High (pH 8-9.5) 2.66 7.73 -9.53 0 5 0 41 286.379 4 ↓

Analogs

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Popular Name: 2-[4-[(1S)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridine-3-carbaldehyde 2-[4-[(1S)-1-methylpropyl]pipera…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 9.6 -40.6 1 5 1 42 287.387 4 ↓
Hi High (pH 8-9.5) 2.66 7.8 -9.56 0 5 0 41 286.379 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-[4-[(1R)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]methanol [2-[4-[(1R)-1-methylpropyl]piper…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 7.17 -36.53 2 5 1 45 289.403 4 ↓
Hi High (pH 8-9.5) 2.20 5.34 -11.31 1 5 0 44 288.395 4 ↓
Lo Low (pH 4.5-6) 2.20 7.65 -79.65 3 5 2 46 290.411 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-[4-[(1S)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]methanol [2-[4-[(1S)-1-methylpropyl]piper…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 7.2 -36.43 2 5 1 45 289.403 4 ↓
Hi High (pH 8-9.5) 2.20 5.39 -11.31 1 5 0 44 288.395 4 ↓
Lo Low (pH 4.5-6) 2.20 7.68 -79.52 3 5 2 46 290.411 4 ↓

Analogs

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Popular Name: 3-(chloromethyl)-2-[4-[(1R)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridine 3-(chloromethyl)-2-[4-[(1R)-1-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 11.12 -34.7 1 4 1 25 307.849 4 ↓
Hi High (pH 8-9.5) 3.44 9.28 -8.68 0 4 0 24 306.841 4 ↓
Lo Low (pH 4.5-6) 3.44 11.6 -81.09 2 4 2 26 308.857 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(chloromethyl)-2-[4-[(1S)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridine 3-(chloromethyl)-2-[4-[(1S)-1-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 11.14 -34.53 1 4 1 25 307.849 4 ↓
Hi High (pH 8-9.5) 3.44 9.33 -8.67 0 4 0 24 306.841 4 ↓
Lo Low (pH 4.5-6) 3.44 11.62 -80.98 2 4 2 26 308.857 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-[4-[(1R)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]methanamine [2-[4-[(1R)-1-methylpropyl]piper…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.05 7.88 -103.83 4 5 2 53 289.427 4 ↓
Hi High (pH 8-9.5) 2.05 5.65 -9.21 2 5 0 50 287.411 4 ↓
Hi High (pH 8-9.5) 2.05 6.07 -52.7 3 5 1 51 288.419 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-[4-[(1S)-1-methylpropyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]methanamine [2-[4-[(1S)-1-methylpropyl]piper…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.05 7.9 -104.19 4 5 2 53 289.427 4 ↓
Hi High (pH 8-9.5) 2.05 5.69 -9.16 2 5 0 50 287.411 4 ↓
Hi High (pH 8-9.5) 2.05 6.13 -52.64 3 5 1 51 288.419 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-isobutylpiperazin-1-yl)imidazo[1,2-a]pyridine-3-carbaldehyde 2-(4-isobutylpiperazin-1-yl)imid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 9.95 -42.33 1 5 1 42 287.387 4 ↓
Hi High (pH 8-9.5) 2.57 8.02 -9.74 0 5 0 41 286.379 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-(4-isobutylpiperazin-1-yl)imidazo[1,2-a]pyridin-3-yl]methanol [2-(4-isobutylpiperazin-1-yl)imi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 7.54 -37.97 2 5 1 45 289.403 4 ↓
Hi High (pH 8-9.5) 2.12 5.61 -11.48 1 5 0 44 288.395 4 ↓
Lo Low (pH 4.5-6) 2.12 8.02 -81.83 3 5 2 46 290.411 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-(chloromethyl)-2-(4-isobutylpiperazin-1-yl)imidazo[1,2-a]pyridine 3-(chloromethyl)-2-(4-isobutylpi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.36 11.49 -36.19 1 4 1 25 307.849 4 ↓
Hi High (pH 8-9.5) 3.36 9.55 -8.9 0 4 0 24 306.841 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-(4-isobutylpiperazin-1-yl)imidazo[1,2-a]pyridin-3-yl]methanamine [2-(4-isobutylpiperazin-1-yl)imi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 8.25 -105.66 4 5 2 53 289.427 4 ↓
Hi High (pH 8-9.5) 1.96 5.93 -9.44 2 5 0 50 287.411 4 ↓
Hi High (pH 8-9.5) 1.96 7.86 -37.01 3 5 1 51 288.419 4 ↓

Analogs

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Popular Name: tert-butyl tert-butyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.45 9.39 -10.81 0 7 0 74 327.388 3 ↓

Analogs

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Popular Name: 2-(4-tert-butylpiperazin-1-yl)imidazo[1,2-a]pyridine-3-carbaldehyde 2-(4-tert-butylpiperazin-1-yl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.63 9.22 -39.6 1 5 1 42 287.387 3 ↓
Hi High (pH 8-9.5) 2.63 7.17 -9.72 0 5 0 41 286.379 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [2-(4-tert-butylpiperazin-1-yl)imidazo[1,2-a]pyridin-3-yl]methanol [2-(4-tert-butylpiperazin-1-yl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.18 6.83 -35.79 2 5 1 45 289.403 3 ↓
Hi High (pH 8-9.5) 2.18 4.77 -11.61 1 5 0 44 288.395 3 ↓
Lo Low (pH 4.5-6) 2.18 7.31 -78.74 3 5 2 46 290.411 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-tert-butylpiperazin-1-yl)-3-(chloromethyl)imidazo[1,2-a]pyridine 2-(4-tert-butylpiperazin-1-yl)-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.42 10.77 -33.91 1 4 1 25 307.849 3 ↓
Hi High (pH 8-9.5) 3.42 8.71 -8.89 0 4 0 24 306.841 3 ↓
Lo Low (pH 4.5-6) 3.42 11.25 -80.12 2 4 2 26 308.857 3 ↓

Analogs

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Popular Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]imidazo[1,2-a]pyridine-3-carboxylic 2-[4-(2-hydroxyethyl)piperazin-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 2.67 -64.46 1 7 -1 84 289.315 4 ↓
Mid Mid (pH 6-8) 0.60 3.64 -32.59 2 7 0 85 290.323 4 ↓
Mid Mid (pH 6-8) 0.60 3.14 -50.71 2 7 0 85 290.323 4 ↓

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Structural Results Found: (before additional filtering)

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