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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: (3R)-N-[(4-methoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(4-methoxyphenyl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.03 7.34 -13.25 1 6 0 67 382.489 5 ↓

Analogs

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Popular Name: (3S)-N-[(4-methoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(4-methoxyphenyl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.03 7.34 -13.27 1 6 0 67 382.489 5 ↓

Analogs

15770450
15770450
15770452
15770452

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Popular Name: (3R)-N-[(4-ethoxy-3-methoxy-phenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(4-ethoxy-3-methoxy-phen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 8.16 -15.55 1 7 0 77 426.542 7 ↓

Analogs

15770450
15770450
15770452
15770452

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(4-ethoxy-3-methoxy-phenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(4-ethoxy-3-methoxy-phen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 8.16 -15.59 1 7 0 77 426.542 7 ↓

Analogs

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Popular Name: (3R)-N-[(2,4-dimethoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(2,4-dimethoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.67 -14.32 1 7 0 77 412.515 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(2,4-dimethoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(2,4-dimethoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.67 -14 1 7 0 77 412.515 6 ↓

Analogs

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Popular Name: (3R)-N-[(2,5-dimethoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(2,5-dimethoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.65 -14.09 1 7 0 77 412.515 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(2,5-dimethoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(2,5-dimethoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 6.65 -13.9 1 7 0 77 412.515 6 ↓

Analogs

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Popular Name: (3R)-N-[(4-dimethylaminophenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(4-dimethylaminophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.08 8.47 -12.76 1 6 0 61 395.532 5 ↓
Lo Low (pH 4.5-6) 3.08 9.21 -88.31 2 6 0 63 396.54 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(4-dimethylaminophenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(4-dimethylaminophenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.08 8.47 -12.76 1 6 0 61 395.532 5 ↓
Lo Low (pH 4.5-6) 3.08 9.21 -88.21 2 6 0 63 396.54 5 ↓

Analogs

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Popular Name: (3R)-N-[(3-fluorophenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(3-fluorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 8.11 -12.9 1 5 0 58 370.453 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(3-fluorophenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(3-fluorophenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 8.11 -12.97 1 5 0 58 370.453 4 ↓

Analogs

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Popular Name: (3R)-N-[(4-butoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3R)-N-[(4-butoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.47 9.85 -12.84 1 6 0 67 424.57 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[(4-butoxyphenyl)methyl]-1-thiazolo[5,4-b]pyridin-2-yl-piperidine-3-carboxamide (3S)-N-[(4-butoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.47 9.85 -12.8 1 6 0 67 424.57 8 ↓

Parameters Provided:

ring.id = 392306
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 392306 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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