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ZINC Item

Suppliers, Protomers, & Similar Substances

11797864

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[2-[4-(m-tolylmethoxy)phenyl]thiazol-4-yl]acetic 2-[2-[4-(m-tolylmethoxy)phenyl]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.53	0.31	-54.87	0	4	-1	62	338.408	6	↓ MOL2 SDF SMILES Flexibase

11799075

Analogs

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Popular Name: 2-[2-[4-[(2-chloro-6-fluoro-phenyl)methoxy]phenyl]thiazol-4-yl]acetic 2-[2-[4-[(2-chloro-6-fluoro-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.85	0.53	-57.03	0	4	-1	62	376.816	6	↓ MOL2 SDF SMILES Flexibase

11800045

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-benzyloxy-3-chloro-5-methoxy-phenyl)thiazole-4-carboxylic 2-(4-benzyloxy-3-chloro-5-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.64	-0.16	-56.14	0	5	-1	71	374.825	6	↓ MOL2 SDF SMILES Flexibase

35895164

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	9.57	-11.27	0	5	0	58	389.86	7	↓ MOL2 SDF SMILES Flexibase

35895165

Analogs

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Popular Name: 2-[4-[(2-chlorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[4-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.88	9.7	-55.22	0	4	-1	62	344.799	5	↓ MOL2 SDF SMILES Flexibase

35895168

Analogs

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Popular Name: 2-[2-chloro-4-[(4-fluorophenyl)methoxy]phenyl]thiazole-4-carboxylic 2-[2-chloro-4-[(4-fluorophenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.02	10.05	-59.29	0	4	-1	62	362.789	5	↓ MOL2 SDF SMILES Flexibase

35895170

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4-benzyloxy-2-chloro-phenyl)thiazole-4-carboxylic 2-(4-benzyloxy-2-chloro-phenyl)t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.86	9.98	-58.23	0	4	-1	62	344.799	5	↓ MOL2 SDF SMILES Flexibase

35895176

Analogs

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Popular Name: N-isobutyl-2-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-isobutyl-2-[4-[[4-(trifluorome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.89	10.2	-10.51	1	4	0	51	434.483	8	↓ MOL2 SDF SMILES Flexibase

35895178

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-isopropyl-2-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-isopropyl-2-[4-[[4-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.44	9.51	-10.91	1	4	0	51	420.456	7	↓ MOL2 SDF SMILES Flexibase

35895195

Analogs

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Popular Name: 2-[4-[(2-fluorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[4-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	9.37	-8.83	1	4	0	51	384.476	7	↓ MOL2 SDF SMILES Flexibase

35895199

Analogs

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Popular Name: 2-[4-[(2-fluorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[4-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.66	8.67	-9.17	1	4	0	51	370.449	6	↓ MOL2 SDF SMILES Flexibase

35895204

Analogs

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Popular Name: N-ethyl-2-[4-[(2-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-ethyl-2-[4-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.36	7.85	-9.22	1	4	0	51	356.422	6	↓ MOL2 SDF SMILES Flexibase

35895208

Analogs

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Popular Name: 2-[4-[(2-fluorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[4-[(2-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.87	8.61	-9	1	4	0	51	370.449	7	↓ MOL2 SDF SMILES Flexibase

35895214

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-allyl-2-[4-[(2-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.63	8.41	-8.93	1	4	0	51	368.433	7	↓ MOL2 SDF SMILES Flexibase

11800173

Analogs

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Popular Name: 2-(4-benzyloxyphenyl)thiazole-4-carboxylic 2-(4-benzyloxyphenyl)thiazole-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.25	-0.47	-56.3	0	4	-1	62	310.354	5	↓ MOL2 SDF SMILES Flexibase

35895220

Analogs

35895223

Draw Identity 99% 90% 80% 70%

Popular Name: N,N-diethyl-2-[4-[(2-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N,N-diethyl-2-[4-[(2-fluoropheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.98	11.84	-9.51	0	4	0	42	384.476	7	↓ MOL2 SDF SMILES Flexibase

35895223

Analogs

35895220

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-2-[4-[(2-fluorophenyl)methoxy]phenyl]-N-methyl-thiazole-4-carboxamide N-ethyl-2-[4-[(2-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.61	10.57	-9.78	0	4	0	42	370.449	6	↓ MOL2 SDF SMILES Flexibase

35895241

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(4-fluorophenyl)methoxy]phenyl]-N-isopentyl-thiazole-4-carboxamide 2-[4-[(4-fluorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.69	9.8	-10.28	1	4	0	51	398.503	8	↓ MOL2 SDF SMILES Flexibase

35895249

Analogs

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Popular Name: 2-(4-benzyloxyphenyl)-N-ethyl-thiazole-4-carboxamide 2-(4-benzyloxyphenyl)-N-ethyl-th…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.25	7.68	-9.52	1	4	0	51	338.432	6	↓ MOL2 SDF SMILES Flexibase

35895251

Analogs

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Popular Name: 2-(4-benzyloxyphenyl)-N-isopentyl-thiazole-4-carboxamide 2-(4-benzyloxyphenyl)-N-isopenty…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.52	9.73	-9.15	1	4	0	51	380.513	8	↓ MOL2 SDF SMILES Flexibase

35895264

Analogs

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Popular Name: 2-[4-[(2,5-dimethylphenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[4-[(2,5-dimethylphenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.37	9.85	-9.86	1	4	0	51	380.513	6	↓ MOL2 SDF SMILES Flexibase

35895265

Analogs

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Popular Name: 2-[4-[(2,5-dimethylphenyl)methoxy]phenyl]-N-ethyl-thiazole-4-carboxamide 2-[4-[(2,5-dimethylphenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.07	9.03	-9.9	1	4	0	51	366.486	6	↓ MOL2 SDF SMILES Flexibase

35895267

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-isopropyl-2-[4-(m-tolylmethoxy)phenyl]thiazole-4-carboxamide N-isopropyl-2-[4-(m-tolylmethoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	9.17	-9.61	1	4	0	51	366.486	6	↓ MOL2 SDF SMILES Flexibase

35895268

Analogs

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Popular Name: N-ethyl-2-[4-(m-tolylmethoxy)phenyl]thiazole-4-carboxamide N-ethyl-2-[4-(m-tolylmethoxy)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.67	8.35	-9.57	1	4	0	51	352.459	6	↓ MOL2 SDF SMILES Flexibase

35895271

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-allyl-2-[4-(m-tolylmethoxy)phenyl]thiazole-4-carboxamide N-allyl-2-[4-(m-tolylmethoxy)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.94	8.91	-9.36	1	4	0	51	364.47	7	↓ MOL2 SDF SMILES Flexibase

35895278

Analogs

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Popular Name: N-allyl-2-[4-[(3-chlorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(3-chlorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.17	8.76	-9.85	1	4	0	51	384.888	7	↓ MOL2 SDF SMILES Flexibase

35895279

Analogs

35895281

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(3-chlorophenyl)methoxy]phenyl]-N,N-diethyl-thiazole-4-carboxamide 2-[4-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.52	12.18	-10.19	0	4	0	42	400.931	7	↓ MOL2 SDF SMILES Flexibase

35895281

Analogs

35895279

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(3-chlorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[4-[(3-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	10.92	-10.47	0	4	0	42	386.904	6	↓ MOL2 SDF SMILES Flexibase

35895283

Analogs

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Popular Name: N-ethyl-2-[4-[(3-fluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-ethyl-2-[4-[(3-fluorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.39	7.75	-10.77	1	4	0	51	356.422	6	↓ MOL2 SDF SMILES Flexibase

35895289

Analogs

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Popular Name: 2-[4-[(2-chlorophenyl)methoxy]phenyl]-N-isobutyl-thiazole-4-carboxamide 2-[4-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.62	9.78	-8.43	1	4	0	51	400.931	7	↓ MOL2 SDF SMILES Flexibase

35895295

Analogs

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Popular Name: 2-[4-[(2-chlorophenyl)methoxy]phenyl]-N-isopentyl-thiazole-4-carboxamide 2-[4-[(2-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	6.15	10.31	-8.45	1	4	0	51	414.958	8	↓ MOL2 SDF SMILES Flexibase

35895296

Analogs

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Popular Name: N-allyl-2-[4-[(2-chlorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(2-chlorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	8.83	-8.52	1	4	0	51	384.888	7	↓ MOL2 SDF SMILES Flexibase

35895302

Analogs

34711904

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(2,6-difluorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[4-[(2,6-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.72	10.45	-11.21	0	4	0	42	388.439	6	↓ MOL2 SDF SMILES Flexibase

35895319

Analogs

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Popular Name: N-allyl-2-[4-[(3,4-difluorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(3,4-difluoropheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	8.37	-12.39	1	4	0	51	386.423	7	↓ MOL2 SDF SMILES Flexibase

35895324

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-methoxyethyl)-2-[4-[(3-methoxyphenyl)methoxy]phenyl]thiazole-4-carboxamide N-(2-methoxyethyl)-2-[4-[(3-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	6.07	-12.22	1	6	0	70	398.484	9	↓ MOL2 SDF SMILES Flexibase

35895328

Analogs

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Popular Name: 2-[4-[(3-methoxyphenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[4-[(3-methoxyphenyl)methoxy]p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	7.75	-11.03	1	5	0	60	382.485	8	↓ MOL2 SDF SMILES Flexibase

35895331

Analogs

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Popular Name: N-isopentyl-2-[4-[(3-methoxyphenyl)methoxy]phenyl]thiazole-4-carboxamide N-isopentyl-2-[4-[(3-methoxyphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.56	9.03	-10.81	1	5	0	60	410.539	9	↓ MOL2 SDF SMILES Flexibase

35895332

Analogs

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Popular Name: N-allyl-2-[4-[(3-methoxyphenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(3-methoxyphenyl)m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.55	7.54	-10.96	1	5	0	60	380.469	8	↓ MOL2 SDF SMILES Flexibase

35895335

Analogs

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Popular Name: N-isobutyl-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]thiazole-4-carboxamide N-isobutyl-2-[4-[[3-(trifluorome…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.86	10.22	-10.64	1	4	0	51	434.483	8	↓ MOL2 SDF SMILES Flexibase

35895342

Analogs

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Popular Name: 2-[4-[(4-chlorophenyl)methoxy]phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[4-[(4-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.53	7.29	-11	1	5	0	60	402.903	8	↓ MOL2 SDF SMILES Flexibase

35895344

Analogs

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Popular Name: 2-[4-[(4-chlorophenyl)methoxy]phenyl]-N-isopropyl-thiazole-4-carboxamide 2-[4-[(4-chlorophenyl)methoxy]ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.22	9.02	-10	1	4	0	51	386.904	6	↓ MOL2 SDF SMILES Flexibase

35895355

Analogs

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Popular Name: N-allyl-2-[4-[(4-chlorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(4-chlorophenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.19	8.77	-9.82	1	4	0	51	384.888	7	↓ MOL2 SDF SMILES Flexibase

35895378

Analogs

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Popular Name: 2-[4-[(3,5-difluorophenyl)methoxy]phenyl]-N-propyl-thiazole-4-carboxamide 2-[4-[(3,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.01	8.58	-10.4	1	4	0	51	388.439	7	↓ MOL2 SDF SMILES Flexibase

35895393

Analogs

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Popular Name: 2-[4-[(2,5-difluorophenyl)methoxy]phenyl]-N-ethyl-N-methyl-thiazole-4-carboxamide 2-[4-[(2,5-difluorophenyl)methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	10.63	-9.93	0	4	0	42	388.439	6	↓ MOL2 SDF SMILES Flexibase

35895400

Analogs

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Popular Name: N-allyl-2-[4-[(3,4-dichlorophenyl)methoxy]phenyl]thiazole-4-carboxamide N-allyl-2-[4-[(3,4-dichloropheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.80	9.21	-10.71	1	4	0	51	419.333	7	↓ MOL2 SDF SMILES Flexibase

35895436

Analogs

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Popular Name: 2-[4-[(4-fluorophenyl)methoxy]-3-methoxy-phenyl]-N-propyl-thiazole-4-carboxamide 2-[4-[(4-fluorophenyl)methoxy]-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.50	8.42	-11.76	1	5	0	60	400.475	8	↓ MOL2 SDF SMILES Flexibase

35895438

Analogs

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Popular Name: N-(2-dimethylaminoethyl)-2-[4-[(4-fluorophenyl)methoxy]-3-methoxy-phenyl]thiazole-4-carboxamide N-(2-dimethylaminoethyl)-2-[4-[(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	8.95	-45.94	2	6	1	65	430.525	9	↓ MOL2 SDF SMILES Flexibase

35895442

Analogs

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Popular Name: 2-(4-benzyloxy-3-methoxy-phenyl)-N-(2-methoxyethyl)thiazole-4-carboxamide 2-(4-benzyloxy-3-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.45	6.67	-12.18	1	6	0	70	398.484	9	↓ MOL2 SDF SMILES Flexibase

35895460

Analogs

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Popular Name: 2-[4-[(3-chlorophenyl)methoxy]-3-methoxy-phenyl]-N-(2-methoxyethyl)thiazole-4-carboxamide 2-[4-[(3-chlorophenyl)methoxy]-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.10	7.18	-12.48	1	6	0	70	432.929	9	↓ MOL2 SDF SMILES Flexibase

35895463

Analogs

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Popular Name: 2-[4-[(3-chlorophenyl)methoxy]-3-methoxy-phenyl]-N-(2-dimethylaminoethyl)thiazole-4-carboxamide 2-[4-[(3-chlorophenyl)methoxy]-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	9.39	-45.18	2	6	1	65	446.98	9	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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