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Analogs

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Popular Name: 4-chloro-1-(3-chloro-2-pyridyl)pyrazolo[3,4-d]pyrimidine 4-chloro-1-(3-chloro-2-pyridyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 7.5 -10.82 0 5 0 57 266.091 1 ↓

Analogs

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Popular Name: 4-chloro-1-(3-methyl-2-pyridyl)pyrazolo[3,4-d]pyrimidine 4-chloro-1-(3-methyl-2-pyridyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.09 7.3 -11.27 0 5 0 57 245.673 1 ↓

Analogs

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Popular Name: N-ethyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-ethyl-1-(2-pyridyl)pyrazolo[3,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.24 6.91 -14.09 1 6 0 69 240.27 3 ↓

Analogs

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Popular Name: N-methyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-methyl-1-(2-pyridyl)pyrazolo[3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.87 6.07 -14.86 1 6 0 69 226.243 2 ↓

Analogs

41529145
41529145

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Popular Name: N-isopropyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-isopropyl-1-(2-pyridyl)pyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 7.71 -13.97 1 6 0 69 254.297 3 ↓

Analogs

41529118
41529118
41529099
41529099

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Popular Name: N-[(1R)-1-methylpropyl]-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-[(1R)-1-methylpropyl]-1-(2-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.07 8.61 -13.76 1 6 0 69 268.324 4 ↓

Analogs

41529099
41529099
41529115
41529115

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Popular Name: N-[(1S)-1-methylpropyl]-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-[(1S)-1-methylpropyl]-1-(2-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.07 8.61 -13.75 1 6 0 69 268.324 4 ↓

Analogs

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Popular Name: N-propyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-propyl-1-(2-pyridyl)pyrazolo[3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 7.68 -13.98 1 6 0 69 254.297 4 ↓

Analogs

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Popular Name: N-allyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-allyl-1-(2-pyridyl)pyrazolo[3,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 7.46 -13.78 1 6 0 69 252.281 4 ↓

Analogs

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Popular Name: N-isobutyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-isobutyl-1-(2-pyridyl)pyrazolo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 8.37 -13.67 1 6 0 69 268.324 4 ↓

Analogs

41529136
41529136

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Popular Name: N-isopentyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-isopentyl-1-(2-pyridyl)pyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 8.95 -13.8 1 6 0 69 282.351 5 ↓

Analogs

41529132
41529132

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Popular Name: N-butyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-butyl-1-(2-pyridyl)pyrazolo[3,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 8.45 -13.88 1 6 0 69 268.324 5 ↓

Analogs

41529111
41529111

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Popular Name: N-tert-butyl-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-tert-butyl-1-(2-pyridyl)pyrazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.05 8.76 -13.37 1 6 0 69 268.324 3 ↓

Analogs

41529151
41529151

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Popular Name: N-(3-ethoxypropyl)-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-(3-ethoxypropyl)-1-(2-pyridyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 7.7 -14.72 1 7 0 78 298.35 7 ↓

Analogs

41529148
41529148

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Popular Name: N-(3-methoxypropyl)-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-(3-methoxypropyl)-1-(2-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.12 6.74 -14.8 1 7 0 78 284.323 6 ↓

Analogs

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Popular Name: 2-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethanol 2-[[1-(2-pyridyl)pyrazolo[3,4-d]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.23 3.57 -15.79 2 7 0 89 256.269 4 ↓

Analogs

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Popular Name: 3-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-ol 3-[[1-(2-pyridyl)pyrazolo[3,4-d]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.50 4.32 -15.55 2 7 0 89 270.296 5 ↓

Analogs

41531891
41531891

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Popular Name: (2S)-1-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-2-ol (2S)-1-[[1-(2-pyridyl)pyrazolo[3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 4.34 -15.28 2 7 0 89 270.296 4 ↓

Analogs

41531888
41531888

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Popular Name: (2R)-1-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-2-ol (2R)-1-[[1-(2-pyridyl)pyrazolo[3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 4.39 -15.23 2 7 0 89 270.296 4 ↓

Analogs

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Popular Name: N-(2-methoxyethyl)-1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-amine N-(2-methoxyethyl)-1-(2-pyridyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 5.98 -14.56 1 7 0 78 270.296 5 ↓

Analogs

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Popular Name: N,N-dimethyl-N'-[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]ethane-1,2-diamine N,N-dimethyl-N'-[1-(2-pyridyl)py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.90 8.19 -51.66 2 7 1 73 284.347 5 ↓
Hi High (pH 8-9.5) 0.90 5.72 -14.3 1 7 0 72 283.339 5 ↓

Analogs

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Popular Name: N,N-dimethyl-N'-[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]propane-1,3-diamine N,N-dimethyl-N'-[1-(2-pyridyl)py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.17 8.98 -51.24 2 7 1 73 298.374 6 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.73 7 -14.56 1 8 0 95 284.279 5 ↓

Analogs

41531921
41531921

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 9.2 -13.42 1 8 0 95 326.36 6 ↓

Analogs

41531918
41531918

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 9.2 -13.51 1 8 0 95 326.36 6 ↓

Analogs

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Popular Name: N,N-dimethyl-2-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]acetamide N,N-dimethyl-2-[[1-(2-pyridyl)py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.22 6.47 -16.5 1 8 0 89 297.322 4 ↓

Analogs

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Popular Name: N-ethyl-2-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]acetamide N-ethyl-2-[[1-(2-pyridyl)pyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.85 5.37 -16.2 2 8 0 98 297.322 5 ↓

Analogs

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Popular Name: N-isopropyl-2-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]acetamide N-isopropyl-2-[[1-(2-pyridyl)pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 6.19 -16.11 2 8 0 98 311.349 5 ↓

Analogs

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Popular Name: N-methyl-2-[[1-(2-pyridyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]acetamide N-methyl-2-[[1-(2-pyridyl)pyrazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.47 4.53 -16.86 2 8 0 98 283.295 4 ↓

Analogs

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Popular Name: 4-chloro-1-[5-(trifluoromethyl)-2-pyridyl]pyrazolo[3,4-d]pyrimidine 4-chloro-1-[5-(trifluoromethyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 7.57 -8.83 0 5 0 57 299.643 2 ↓

Parameters Provided:

ring.id = 462882
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 462882 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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