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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
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Popular Name: 6-(2-amino-4-pyridyl)-1H-indazol-3-amine 6-(2-amino-4-pyridyl)-1H-indazol…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDPK1-2-E 3-phosphoinositide Dependent Protein Kinase-1 (cluster #2 Of 2), Eukaryotic Eukaryotes 7280 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDPK1_HUMAN O15530 3-phosphoinositide Dependent Protein Kinase-1, Human 7280 0.42 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.54 2.58 -34.72 6 5 1 95 226.263 1 ↓
Mid Mid (pH 6-8) 1.54 2.45 -12.06 5 5 0 94 225.255 1 ↓
Mid Mid (pH 6-8) 1.54 2.93 -36.43 6 5 1 95 226.263 1 ↓

Parameters Provided:

ring.id = 471804
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 471804 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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