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ZINC Item

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53346914

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-2-ethoxy-phenyl)-2-(4,4-diethyl-2,5-dioxo-imidazolidin-1-yl)acetamide N-(3-chloro-2-ethoxy-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.18	5.97	-12.9	2	7	0	88	367.833	7	↓ MOL2 SDF SMILES Flexibase

19452158

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,5-diisopropyl-4-methoxy-phenyl)-2-(4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl)acetamide N-(3,5-diisopropyl-4-methoxy-phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.15	6.48	-19.02	2	7	0	88	375.469	6	↓ MOL2 SDF SMILES Flexibase

12037850

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-(4-methylsulfanylphenyl)-acetamide 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.71	-1.23	-14.89	2	6	0	79	363.483	8	↓ MOL2 SDF SMILES Flexibase

22705383

Analogs

9834510
9834511

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4,4-diethyl-2,5-dioxo-imidazolidin-1-yl)-N-(3,4-difluorophenyl)acetamide 2-(4,4-diethyl-2,5-dioxo-imidazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	5.11	-21.79	2	6	0	79	325.315	5	↓ MOL2 SDF SMILES Flexibase

22705391

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(4,4-diethyl-2,5-dioxo-imidazolidin-1-yl)-N-phenyl-acetamide 2-(4,4-diethyl-2,5-dioxo-imidazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.16	5	-18.4	2	6	0	79	289.335	5	↓ MOL2 SDF SMILES Flexibase

22743401

Analogs

14275923
14275925

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-tert-butylphenyl)-2-[(4S)-2,5-dioxo-4-propyl-imidazolidin-1-yl]acetamide N-(2-tert-butylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.43	6.83	-16.14	2	6	0	79	331.416	6	↓ MOL2 SDF SMILES Flexibase

22743406

Analogs

14275923
14275925

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-tert-butylphenyl)-2-[(4R)-2,5-dioxo-4-propyl-imidazolidin-1-yl]acetamide N-(2-tert-butylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.43	6.83	-16.08	2	6	0	79	331.416	6	↓ MOL2 SDF SMILES Flexibase

22745735

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-(2-fluoro-4-methyl-phenyl)acetamide 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.82	7.18	-16.17	2	6	0	79	349.406	7	↓ MOL2 SDF SMILES Flexibase

36875533

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-[2-(2-methoxyethoxy)-5-(trifluoromethyl)phenyl]acetam 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.05	7.08	-16.83	2	8	0	97	459.465	12	↓ MOL2 SDF SMILES Flexibase

36875550

Analogs

36875565

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-methyl-N-phenyl-acetamide 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.16	8.16	-15.48	1	6	0	70	331.416	7	↓ MOL2 SDF SMILES Flexibase

36875564

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-(4-ethoxy-2-nitro-phenyl)acetamide 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.60	7.76	-13.59	2	10	0	134	406.439	10	↓ MOL2 SDF SMILES Flexibase

36875565

Analogs

36875550

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)-N-ethyl-N-phenyl-acetamide 2-(2,5-dioxo-4,4-dipropyl-imidaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	8.97	-14.94	1	6	0	70	345.443	8	↓ MOL2 SDF SMILES Flexibase

36875568

Analogs

4308974
4308975
4308976

Draw Identity 99% 90% 80% 70%

Popular Name: N-[2-chloro-6-(trifluoromethyl)phenyl]-2-(2,5-dioxo-4,4-dipropyl-imidazolidin-1-yl)acetamide N-[2-chloro-6-(trifluoromethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.76	8.38	-15.31	2	6	0	79	419.831	8	↓ MOL2 SDF SMILES Flexibase

36965170

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-chloro-2-[[2-(2,5-dioxoimidazolidin-1-yl)acetyl]amino]benzoic 4-chloro-2-[[2-(2,5-dioxoimidazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	3.14	-51.22	2	8	-1	119	310.673	4	↓ MOL2 SDF SMILES Flexibase

36965172

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-(2,5-dioxoimidazolidin-1-yl)acetyl]amino]benzoic 2-[[2-(2,5-dioxoimidazolidin-1-y…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.39	2.59	-55.09	2	8	-1	119	276.228	4	↓ MOL2 SDF SMILES Flexibase

36967892

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[[2-(2,5-dioxoimidazolidin-1-yl)acetyl]amino]phenyl]acetic 2-[4-[[2-(2,5-dioxoimidazolidin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.23	3.05	-59.35	2	8	-1	119	290.255	5	↓ MOL2 SDF SMILES Flexibase

36974410

Analogs

49378353
49379412
6617750
3370111
5365541

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-(2,5-dioxoimidazolidin-1-yl)acetyl]-methyl-amino]benzoic 2-[[2-(2,5-dioxoimidazolidin-1-y…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.27	4.55	-66.57	1	8	-1	110	290.255	4	↓ MOL2 SDF SMILES Flexibase

13274785

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-4,5-dimethoxy-benzoic 2-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.21	2.35	-106.64	2	12	-2	177	407.335	9	↓ MOL2 SDF SMILES Flexibase

13274786

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-4,5-dimethoxy-benzoic 2-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.21	2.29	-104.74	2	12	-2	177	407.335	9	↓ MOL2 SDF SMILES Flexibase

13274789

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-chloro-2-methoxy-benzoic 4-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.70	3.38	-115.28	2	11	-2	168	411.754	8	↓ MOL2 SDF SMILES Flexibase

13274790

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-chloro-2-methoxy-benzoic 4-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.70	3.47	-115.13	2	11	-2	168	411.754	8	↓ MOL2 SDF SMILES Flexibase

13274791

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(4S)-1-[2-[[4-(carboxymethyl)phenyl]amino]-2-oxo-ethyl]-2,5-dioxo-imidazolidin-4-yl]propanoic 3-[(4S)-1-[2-[[4-(carboxymethyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.45	3.5	-114.33	2	10	-2	159	361.31	8	↓ MOL2 SDF SMILES Flexibase

13274792

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(4R)-1-[2-[[4-(carboxymethyl)phenyl]amino]-2-oxo-ethyl]-2,5-dioxo-imidazolidin-4-yl]propanoic 3-[(4R)-1-[2-[[4-(carboxymethyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.45	3.56	-115.19	2	10	-2	159	361.31	8	↓ MOL2 SDF SMILES Flexibase

13274793

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-chloro-benzoic 2-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.82	3.62	-98.82	2	10	-2	159	381.728	7	↓ MOL2 SDF SMILES Flexibase

13274794

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-chloro-benzoic 2-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.82	3.56	-101.64	2	10	-2	159	381.728	7	↓ MOL2 SDF SMILES Flexibase

13274795

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-3-methyl-benzoic 2-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.37	3.86	-107.13	2	10	-2	159	361.31	7	↓ MOL2 SDF SMILES Flexibase

13274796

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-3-methyl-benzoic 2-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.37	3.85	-112.88	2	10	-2	159	361.31	7	↓ MOL2 SDF SMILES Flexibase

13274797

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-iodo-benzoic 2-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	4.2	-98.97	2	10	-2	159	473.179	7	↓ MOL2 SDF SMILES Flexibase

13274798

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-5-iodo-benzoic 2-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	4.16	-101.91	2	10	-2	159	473.179	7	↓ MOL2 SDF SMILES Flexibase

13274799

Analogs

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Popular Name: 2-[[2-[(4S)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-4-fluoro-benzoic 2-[[2-[(4S)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.30	3.18	-98.05	2	10	-2	159	365.273	7	↓ MOL2 SDF SMILES Flexibase

13274800

Analogs

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Popular Name: 2-[[2-[(4R)-4-(2-carboxyethyl)-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-4-fluoro-benzoic 2-[[2-[(4R)-4-(2-carboxyethyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.30	3.18	-103.14	2	10	-2	159	365.273	7	↓ MOL2 SDF SMILES Flexibase

36978130

Analogs

16805954

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[2-(2,5-dioxoimidazolidin-1-yl)acetyl]amino]-3-methyl-benzoic 4-[[2-(2,5-dioxoimidazolidin-1-y…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.63	3.16	-64.23	2	8	-1	119	290.255	4	↓ MOL2 SDF SMILES Flexibase

57915839

Analogs

25806984
8274199
7287576

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Popular Name: 3-[[2-[(4R)-4-hexyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 3-[[2-[(4R)-4-hexyl-4-methyl-2,5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	5.28	-26.08	3	8	0	108	388.468	9	↓ MOL2 SDF SMILES Flexibase

57915841

Analogs

25806984
8274199
7287576

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[[2-[(4S)-4-hexyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 3-[[2-[(4S)-4-hexyl-4-methyl-2,5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.90	5.36	-26.77	3	8	0	108	388.468	9	↓ MOL2 SDF SMILES Flexibase

57918409

Analogs

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Popular Name: 4-[[2-[(4R)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 4-[[2-[(4R)-4-isobutyl-4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.63	3.42	-22.67	3	8	0	108	360.414	6	↓ MOL2 SDF SMILES Flexibase

57918418

Analogs

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Popular Name: 4-[[2-[(4S)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 4-[[2-[(4S)-4-isobutyl-4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.63	3.96	-22.98	3	8	0	108	360.414	6	↓ MOL2 SDF SMILES Flexibase

57918437

Analogs

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Popular Name: N-ethyl-3-[[2-[(4R)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]benzamide N-ethyl-3-[[2-[(4R)-4-isobutyl-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.35	-24.53	3	8	0	108	374.441	7	↓ MOL2 SDF SMILES Flexibase

57918442

Analogs

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Popular Name: N-ethyl-3-[[2-[(4S)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]benzamide N-ethyl-3-[[2-[(4S)-4-isobutyl-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	4.48	-25.36	3	8	0	108	374.441	7	↓ MOL2 SDF SMILES Flexibase

57918447

Analogs

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Popular Name: 3-[[2-[(4R)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 3-[[2-[(4R)-4-isobutyl-4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	3.88	-25.95	3	8	0	108	360.414	6	↓ MOL2 SDF SMILES Flexibase

57918455

Analogs

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Popular Name: 3-[[2-[(4S)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetyl]amino]-N-methyl-benzamide 3-[[2-[(4S)-4-isobutyl-4-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	3.43	-26.59	3	8	0	108	360.414	6	↓ MOL2 SDF SMILES Flexibase

57918500

Analogs

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Popular Name: N-(5-acetamido-2-methoxy-phenyl)-2-[(4R)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetamide N-(5-acetamido-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	3.85	-17.98	3	9	0	117	390.44	7	↓ MOL2 SDF SMILES Flexibase

57918504

Analogs

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Popular Name: N-(5-acetamido-2-methoxy-phenyl)-2-[(4S)-4-isobutyl-4-methyl-2,5-dioxo-imidazolidin-1-yl]acetamide N-(5-acetamido-2-methoxy-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	3.43	-18.1	3	9	0	117	390.44	7	↓ MOL2 SDF SMILES Flexibase

60504707

Analogs

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Popular Name: 2-(2,5-dioxoimidazolidin-1-yl)-N-phenyl-acetamide 2-(2,5-dioxoimidazolidin-1-yl)-N…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.35	1.71	-16.73	2	6	0	79	233.227	3	↓ MOL2 SDF SMILES Flexibase

14246810

Analogs

14246811

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Popular Name: N-(4-iodo-2-methyl-phenyl)-2-[(4S)-4-isopropyl-2,5-dioxo-imidazolidin-1-yl]acetamide N-(4-iodo-2-methyl-phenyl)-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	6.12	-13.75	2	6	0	79	415.231	4	↓ MOL2 SDF SMILES Flexibase

14246811

Analogs

14246810

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Popular Name: N-(4-iodo-2-methyl-phenyl)-2-[(4R)-4-isopropyl-2,5-dioxo-imidazolidin-1-yl]acetamide N-(4-iodo-2-methyl-phenyl)-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	5.89	-13.38	2	6	0	79	415.231	4	↓ MOL2 SDF SMILES Flexibase

14248804

Analogs

14248807

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Popular Name: N-(2-isopropyl-6-methyl-phenyl)-2-[(4S)-4-(2-methylsulfonylethyl)-2,5-dioxo-imidazolidin-1-yl]acetam N-(2-isopropyl-6-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.46	3.76	-25.8	2	8	0	113	395.481	7	↓ MOL2 SDF SMILES Flexibase

14248807

Analogs

14248804

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-isopropyl-6-methyl-phenyl)-2-[(4R)-4-(2-methylsulfonylethyl)-2,5-dioxo-imidazolidin-1-yl]acetam N-(2-isopropyl-6-methyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.46	3.74	-28.65	2	8	0	113	395.481	7	↓ MOL2 SDF SMILES Flexibase

3593806

Analogs

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Popular Name: N-(3-fluorophenyl)-2-[(4S)-4-isobutyl-2,5-diketo-4-methyl-imidazolidin-1-yl]acetamide N-(3-fluorophenyl)-2-[(4S)-4-iso…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	5.22	-17.36	2	6	0	79	321.352	5	↓ MOL2 SDF SMILES Flexibase

3593807

Analogs

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Popular Name: N-(3-fluorophenyl)-2-[(4R)-4-isobutyl-2,5-diketo-4-methyl-imidazolidin-1-yl]acetamide N-(3-fluorophenyl)-2-[(4R)-4-iso…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.57	5.68	-16.75	2	6	0	79	321.352	5	↓ MOL2 SDF SMILES Flexibase

3593808

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-2-[(4S)-4-isobutyl-2,5-diketo-4-methyl-imidazolidin-1-yl]acetamide N-(4-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.49	6.81	-13.57	2	6	0	79	351.834	5	↓ MOL2 SDF SMILES Flexibase

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