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Popular Name: 4-[(2S)-2-(pyrazol-1-ylmethyl)pyrrolidin-1-yl]-2-(4-pyridyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 4-[(2S)-2-(pyrazol-1-ylmethyl)py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 10.2 -13.12 0 6 0 60 346.438 4 ↓
Mid Mid (pH 6-8) 2.40 10.53 -32.23 1 6 1 61 347.446 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(2R)-2-(pyrazol-1-ylmethyl)pyrrolidin-1-yl]-2-(4-pyridyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 4-[(2R)-2-(pyrazol-1-ylmethyl)py…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 10.14 -8.86 0 6 0 60 346.438 4 ↓
Mid Mid (pH 6-8) 2.40 10.48 -28.6 1 6 1 61 347.446 4 ↓

Parameters Provided:

ring.id = 491055
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 491055 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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