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67235206

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(4-ethoxyphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.75	9.92	-18.24	1	8	0	87	432.48	6	↓ MOL2 SDF SMILES Flexibase

67235216

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(3-methoxyphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.35	9.36	-21.62	1	8	0	87	418.453	5	↓ MOL2 SDF SMILES Flexibase

67235219

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(4-ethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.23	11.15	-17.48	1	7	0	78	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235221

Analogs

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Popular Name: N-(2-chlorophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(2-chlorophenyl)-2-(3,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	10.72	-15.24	1	7	0	78	422.872	4	↓ MOL2 SDF SMILES Flexibase

67235224

Analogs

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Popular Name: N-(2,4-dimethoxyphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(2,4-dimethoxyphenyl)-2-(3,5-d…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	8.8	-18.12	1	9	0	97	448.479	6	↓ MOL2 SDF SMILES Flexibase

67235226

Analogs

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetami N-(3-chloro-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	10.81	-16.32	1	7	0	78	436.899	4	↓ MOL2 SDF SMILES Flexibase

67235229

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-[2-(trifluoromethyl)phenyl]acetam 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.17	11.36	-15.25	1	7	0	78	456.424	5	↓ MOL2 SDF SMILES Flexibase

67235230

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2-methoxyphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.33	9.51	-18.06	1	8	0	87	418.453	5	↓ MOL2 SDF SMILES Flexibase

67235232

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.87	11.29	-19.66	1	9	0	104	460.49	7	↓ MOL2 SDF SMILES Flexibase

67235234

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-ethyl-N-(m-tolyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	12.55	-18.87	0	7	0	69	430.508	5	↓ MOL2 SDF SMILES Flexibase

67235247

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2-ethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.19	11.35	-17.6	1	7	0	78	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235251

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.62	11.13	-17.72	1	9	0	104	446.463	6	↓ MOL2 SDF SMILES Flexibase

67235257

Analogs

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Popular Name: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1- N-[2-chloro-5-(trifluoromethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.82	11.71	-16.26	1	7	0	78	490.869	5	↓ MOL2 SDF SMILES Flexibase

67235260

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(4-isopropylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.83	11.64	-17.34	1	7	0	78	430.508	5	↓ MOL2 SDF SMILES Flexibase

67235262

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(4-methoxyphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	9.36	-18.61	1	8	0	87	418.453	5	↓ MOL2 SDF SMILES Flexibase

67235264

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(4-fluorophenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.48	10.13	-18.14	1	7	0	78	406.417	4	↓ MOL2 SDF SMILES Flexibase

67235268

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetam N-(3-chloro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.98	9.92	-21.78	1	8	0	87	452.898	5	↓ MOL2 SDF SMILES Flexibase

67235270

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(o-tolyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.72	10.64	-18.02	1	7	0	78	402.454	4	↓ MOL2 SDF SMILES Flexibase

67235275

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(m-tolyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.74	10.38	-17.47	1	7	0	78	402.454	4	↓ MOL2 SDF SMILES Flexibase

67235277

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamid N-(4-bromo-2-fluoro-phenyl)-2-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.22	10.83	-14.57	1	7	0	78	485.313	4	↓ MOL2 SDF SMILES Flexibase

67235283

Analogs

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Popular Name: N-(3-chlorophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3-chlorophenyl)-2-(3,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	10.59	-19.69	1	7	0	78	422.872	4	↓ MOL2 SDF SMILES Flexibase

67235286

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.00	11.63	-17.73	1	9	0	104	460.49	7	↓ MOL2 SDF SMILES Flexibase

67235288

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2,4,6-trimethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	11.64	-18.33	1	7	0	78	430.508	4	↓ MOL2 SDF SMILES Flexibase

67235291

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetami N-(5-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	11.16	-19.41	1	7	0	78	436.899	4	↓ MOL2 SDF SMILES Flexibase

67235293

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetami N-(2-chloro-4-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.37	11.03	-15.41	1	7	0	78	436.899	4	↓ MOL2 SDF SMILES Flexibase

67235296

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2,6-dimethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.18	10.92	-17.92	1	7	0	78	416.481	4	↓ MOL2 SDF SMILES Flexibase

67235298

Analogs

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Popular Name: N-(2,4-difluorophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(2,4-difluorophenyl)-2-(3,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	10.28	-14.85	1	7	0	78	424.407	4	↓ MOL2 SDF SMILES Flexibase

67235302

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2-fluorophenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	10.21	-16.23	1	7	0	78	406.417	4	↓ MOL2 SDF SMILES Flexibase

67235303

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-methyl-N-phenyl-acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	11.67	-18.78	0	7	0	69	402.454	4	↓ MOL2 SDF SMILES Flexibase

67235306

Analogs

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Popular Name: N-(4-chloro-2-fluoro-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetami N-(4-chloro-2-fluoro-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.09	10.73	-14.56	1	7	0	78	440.862	4	↓ MOL2 SDF SMILES Flexibase

67235310

Analogs

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Popular Name: N-(4-bromophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(4-bromophenyl)-2-(3,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.13	10.69	-17.4	1	7	0	78	467.323	4	↓ MOL2 SDF SMILES Flexibase

67235313

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-phenyl-acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.32	10.06	-18.03	1	7	0	78	388.427	4	↓ MOL2 SDF SMILES Flexibase

67235315

Analogs

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Popular Name: N-(3,5-dimethoxyphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3,5-dimethoxyphenyl)-2-(3,5-d…

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Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	8.67	-20.65	1	9	0	97	448.479	6	↓ MOL2 SDF SMILES Flexibase

67235318

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2-ethyl-6-methyl-phenyl)acetamid 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	12.21	-17.28	1	7	0	78	430.508	5	↓ MOL2 SDF SMILES Flexibase

67235319

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Popular Name: N-(4-chlorophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(4-chlorophenyl)-2-(3,5-dimeth…

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Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.00	10.59	-17.58	1	7	0	78	422.872	4	↓ MOL2 SDF SMILES Flexibase

67235323

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2,5-dimethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	11.26	-17.66	1	7	0	78	416.481	4	↓ MOL2 SDF SMILES Flexibase

67235324

Analogs

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Popular Name: N-(3,4-dimethoxyphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3,4-dimethoxyphenyl)-2-(3,5-d…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.97	9.28	-20.43	1	9	0	97	448.479	6	↓ MOL2 SDF SMILES Flexibase

67235334

Analogs

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Popular Name: N-(3-bromophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3-bromophenyl)-2-(3,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.11	10.69	-19.58	1	7	0	78	467.323	4	↓ MOL2 SDF SMILES Flexibase

67235336

Analogs

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Popular Name: N-(2,5-difluorophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(2,5-difluorophenyl)-2-(3,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	10.28	-17.55	1	7	0	78	424.407	4	↓ MOL2 SDF SMILES Flexibase

67235338

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Popular Name: N-(3-acetylphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3-acetylphenyl)-2-(3,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.19	10.2	-26.3	1	8	0	95	430.464	5	↓ MOL2 SDF SMILES Flexibase

67235359

Analogs

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Popular Name: N-(4-acetylphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(4-acetylphenyl)-2-(3,5-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.22	10.2	-20.05	1	8	0	95	430.464	5	↓ MOL2 SDF SMILES Flexibase

67235366

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(3-fluorophenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.46	10.13	-20.97	1	7	0	78	406.417	4	↓ MOL2 SDF SMILES Flexibase

67235372

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2,3-dimethylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.12	11.15	-17.69	1	7	0	78	416.481	4	↓ MOL2 SDF SMILES Flexibase

67235376

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-methyl-N-(m-tolyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.99	12.04	-19.25	0	7	0	69	416.481	4	↓ MOL2 SDF SMILES Flexibase

67235385

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(2-methoxy-5-methyl-phenyl)acetam 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.75	9.83	-17.61	1	8	0	87	432.48	5	↓ MOL2 SDF SMILES Flexibase

67235386

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(3,4,5-trimethoxyphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.95	9.21	-21.69	1	10	0	106	478.505	7	↓ MOL2 SDF SMILES Flexibase

67235394

Analogs

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Popular Name: 2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)-N-(3-isopropylphenyl)acetamide 2-(3,5-dimethyl-2,4-dioxo-7-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.81	11.62	-17.05	1	7	0	78	430.508	5	↓ MOL2 SDF SMILES Flexibase

67235396

Analogs

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Popular Name: N-(3-cyanophenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(3-cyanophenyl)-2-(3,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.05	10.46	-23.48	1	8	0	102	413.437	4	↓ MOL2 SDF SMILES Flexibase

67235400

Analogs

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Popular Name: N-(2-chloro-6-methyl-phenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetami N-(2-chloro-6-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.35	10.83	-17.64	1	7	0	78	436.899	4	↓ MOL2 SDF SMILES Flexibase

67235402

Analogs

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Popular Name: N-(4-butylphenyl)-2-(3,5-dimethyl-2,4-dioxo-7-phenyl-pyrrolo[3,2-d]pyrimidin-1-yl)acetamide N-(4-butylphenyl)-2-(3,5-dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.18	12.71	-17.35	1	7	0	78	444.535	7	↓ MOL2 SDF SMILES Flexibase

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